(Q33813547)

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Mammalian frataxin: an essential function for cellular viability through an interaction with a preformed ISCU/NFS1/ISD11 iron-sulfur assembly complex.

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21 January 2020

Mammalian frataxin: an essential function for cellular viability through an interaction with a preformed ISCU/NFS1/ISD11 iron-sulfur assembly complex (English)

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21 January 2020

cellular viability

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based on heuristic

inferred from title

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cellular viability

17 September 2023

Marie Wattenhofer-Donzé

5

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21 January 2020

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21 January 2020

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Stéphane Schmucker

1

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21 January 2020

Alain Martelli

2

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21 January 2020

Florent Colin

3

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21 January 2020

Adeline Page

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21 January 2020

Laurence Reutenauer

6

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21 January 2020

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26 January 2011

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21 January 2020

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21 January 2020

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21 January 2020

1

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21 January 2020

e16199

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21 January 2020

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Creative Commons Attribution 4.0 International

26 January 2011

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April 2022 Public Data File from Crossref

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Human frataxin is an allosteric switch that activates the Fe-S cluster biosynthetic complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Molecular details of the yeast frataxin-Isu1 interaction during mitochondrial Fe-S cluster assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Understanding the molecular mechanisms of Friedreich's ataxia to develop therapeutic approaches.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Structural Basis for Fe–S Cluster Assembly and tRNA Thiolation Mediated by IscS Protein–Protein Interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

The N-terminus of mature human frataxin is intrinsically unfolded

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Function and biogenesis of iron-sulphur proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Structural Basis for the Mechanism of Respiratory Complex I

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

The first cellular models based on frataxin missense mutations that reproduce spontaneously the defects associated with Friedreich ataxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Oligomeric yeast frataxin drives assembly of core machinery for mitochondrial iron-sulfur cluster synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Bacterial frataxin CyaY is the gatekeeper of iron-sulfur cluster formation catalyzed by IscS

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Multicellular models of Friedreich ataxia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

The pathogenesis of Friedreich ataxia and the structure and function of frataxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

The in vivo mitochondrial two-step maturation of human frataxin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

In vivo iron-sulfur cluster formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Binding of yeast frataxin to the scaffold for Fe-S cluster biogenesis, Isu

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Frataxin gene point mutations in Italian Friedreich ataxia patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

The structures of frataxin oligomers reveal the mechanism for the delivery and detoxification of iron.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Conformational stability of human frataxin and effect of Friedreich's ataxia-related mutations on protein folding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Monomeric yeast frataxin is an iron-binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Iron-sulfur cluster biosynthesis: characterization of Escherichia coli CYaY as an iron donor for the assembly of [2Fe-2S] clusters in the scaffold IscU.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

The Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Essential role of Isd11 in mitochondrial iron-sulfur cluster synthesis on Isu scaffold proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Structure, function, and formation of biological iron-sulfur clusters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Assembly of human frataxin is a mechanism for detoxifying redox-active iron

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Yeast frataxin solution structure, iron binding, and ferrochelatase interaction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Frataxin acts as an iron chaperone protein to modulate mitochondrial aconitase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Frataxin-mediated iron delivery to ferrochelatase in the final step of heme biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

An interaction between frataxin and Isu1/Nfs1 that is crucial for Fe/S cluster synthesis on Isu1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Iron-sulfur cluster biosynthesis. Characterization of frataxin as an iron donor for assembly of [2Fe-2S] clusters in ISU-type proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Human frataxin maintains mitochondrial iron homeostasis in Saccharomyces cerevisiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Maturation of wild-type and mutated frataxin by the mitochondrial processing peptidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3027643

4 July 2018

Frataxin interacts with Isu1 through a conserved tryptophan in its beta-sheet

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016199

21 January 2018

Mitochondrial frataxin interacts with ISD11 of the NFS1/ISCU complex and multiple mitochondrial chaperones.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016199

21 January 2018

Antioxidant treatment of patients with Friedreich ataxia: four-year follow-up

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016199

21 January 2018

A non-essential function for yeast frataxin in iron-sulfur cluster assembly

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016199

21 January 2018

Structural bases for the interaction of frataxin with the central components of iron-sulphur cluster assembly

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016199

21 January 2018

Solution Structure of the Bacterial Frataxin Ortholog, CyaY

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0016199

21 January 2018

Identifiers

10.1371/JOURNAL.PONE.0016199

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21298097%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

2011PLoSO...616199S

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21298097%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21298097%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

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