(Q33816685)

29 July 2017

title

Regulation of transforming growth factor-beta1 (TGF-β1)-induced pro-fibrotic activities by circadian clock gene BMAL1. (English)

1 reference

29 July 2017

0 references

Chunmin Dong

1

1 reference

29 July 2017

Rafael Gongora

2

1 reference

29 July 2017

Meredith L Sosulski

3

1 reference

29 July 2017

Fayong Luo

4

1 reference

29 July 2017

Cecilia G Sanchez

5

1 reference

29 July 2017

publication date

12 January 2016

1 reference

29 July 2017

1 reference

29 July 2017

volume

17

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29 July 2017

page(s)

4

1 reference

describes a project that uses

29 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5477854/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1186/s12931-016-0320-0

0 references

cites work

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28 July 2018

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Melatonin inhibits endoplasmic reticulum stress and epithelial-mesenchymal transition during bleomycin-induced pulmonary fibrosis in mice

28 July 2018

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The circadian clock regulates rhythmic activation of the NRF2/glutathione-mediated antioxidant defense pathway to modulate pulmonary fibrosis.

28 July 2018

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TGF-β: Titan of Lung Fibrogenesis

28 July 2018

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Circadian clock function is disrupted by environmental tobacco/cigarette smoke, leading to lung inflammation and injury via a SIRT1-BMAL1 pathway

28 July 2018

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Bmal1 suppresses cancer cell invasion by blocking the phosphoinositide 3-kinase-Akt-MMP-2 signaling pathway

28 July 2018

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Role of matrix metaloproteases in idiopathic pulmonary fibrosis

28 July 2018

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TGF-β-Smad3 signaling in emphysema and pulmonary fibrosis: an epigenetic aberration of normal development?

28 July 2018

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Shift work and cancer risk: potential mechanistic roles of circadian disruption, light at night, and sleep deprivation

28 July 2018

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Over-expression of circadian clock gene Bmal1 affects proliferation and the canonical Wnt pathway in NIH-3T3 cells

28 July 2018

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Circadian clock protein cryptochrome regulates the expression of proinflammatory cytokines

28 July 2018

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Circadian disruption alters mouse lung clock gene expression and lung mechanics

28 July 2018

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Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

28 July 2018

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Regulation of TGF-β receptor activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

TGF-β1 modulates the homeostasis between MMPs and MMP inhibitors through p38 MAPK and ERK1/2 in highly invasive breast cancer cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

The circadian molecular clock creates epidermal stem cell heterogeneity.

28 July 2018

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Disrupting the circadian clock: gene-specific effects on aging, cancer, and other phenotypes.

28 July 2018

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Genome-wide and phase-specific DNA-binding rhythms of BMAL1 control circadian output functions in mouse liver

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

Epithelium-specific deletion of TGF-β receptor type II protects mice from bleomycin-induced pulmonary fibrosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

Genome-wide profiling of the core clock protein BMAL1 targets reveals a strict relationship with metabolism

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

Glycogen synthase kinase-3beta negatively regulates TGF-beta1 and Angiotensin II-mediated cellular activity through interaction with Smad3.

28 July 2018

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28 July 2018

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Regulation of BMAL1 protein stability and circadian function by GSK3beta-mediated phosphorylation.

28 July 2018

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Sirtuins, melatonin and circadian rhythms: building a bridge between aging and cancer

28 July 2018

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The regulation of TGFbeta signal transduction

28 July 2018

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Abrogation of TGF-beta1-induced fibroblast-myofibroblast differentiation by histone deacetylase inhibition.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

Non-Smad pathways in TGF-beta signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

The genetics of mammalian circadian order and disorder: implications for physiology and disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

Circadian timing in the lung; a specific role for bronchiolar epithelial cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

Up-regulation of protein L-isoaspartyl methyltransferase expression by lithium is mediated by glycogen synthase kinase-3 inactivation and beta-catenin stabilization

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

TGF-beta1 induced MMP-9 expression in HNSCC cell lines via Smad/MLCK pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

Inhibition of integrin alpha(v)beta6, an activator of latent transforming growth factor-beta, prevents radiation-induced lung fibrosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

Aryl hydrocarbon receptor nuclear translocator-like (BMAL1) is associated with susceptibility to hypertension and type 2 diabetes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

TNF-alpha suppresses the expression of clock genes by interfering with E-box-mediated transcription

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

Dissecting the functions of the mammalian clock protein BMAL1 by tissue-specific rescue in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

Smad3 signaling involved in pulmonary fibrosis and emphysema

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

Molecular components of the mammalian circadian clock

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

Early aging and age-related pathologies in mice deficient in BMAL1, the core componentof the circadian clock

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

Epithelial origin of myofibroblasts during fibrosis in the lung

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

Non-Smad TGF-beta signals

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

TGF-beta1 induces human alveolar epithelial to mesenchymal cell transition (EMT)

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

The orphan nuclear receptor RORalpha regulates circadian transcription of the mammalian core-clock Bmal1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

Smad3 null mice develop airspace enlargement and are resistant to TGF-beta-mediated pulmonary fibrosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

Smad-dependent and Smad-independent pathways in TGF-beta family signalling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

Mop3 is an essential component of the master circadian pacemaker in mammals

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

Emerging potentials for an antioxidant therapy as a new approach to the treatment of systemic sclerosis

28 July 2018

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Role of the CLOCK protein in the mammalian circadian mechanism

28 July 2018

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Establishment of human peripheral lung epithelial cell lines (HPL1) retaining differentiated characteristics and responsiveness to epidermal growth factor, hepatocyte growth factor, and transforming growth factor beta1.

28 July 2018

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Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5477854

Effect of antibody to transforming growth factor beta on bleomycin induced accumulation of lung collagen in mice

28 July 2018

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Growth factors in idiopathic pulmonary fibrosis: relative roles

28 July 2018

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Revealing the pathogenic and aging-related mechanisms of the enigmatic idiopathic pulmonary fibrosis. an integral model.

21 January 2018

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Idiopathic pulmonary fibrosis

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Titration of non-replicating adenovirus as a vector for transducing active TGF-beta1 gene expression causing inflammation and fibrogenesis in the lungs of C57BL/6 mice.

21 January 2018

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Transforming growth factor-beta inhibits the expression of clock genes.

21 January 2018

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Deregulation of selective autophagy during aging and pulmonary fibrosis: the role of TGFβ1.

21 January 2018

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Induction of circadian rhythm in cultured human mesenchymal stem cells by serum shock and cAMP analogs in vitro.

21 January 2018

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Mechanical stretch up-regulates the B-type natriuretic peptide system in human cardiac fibroblasts: a possible defense against transforming growth factor-β mediated fibrosis

21 January 2018

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Metabolic reprogramming and cell fate regulation in alcoholic liver disease

21 January 2018

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Circadian clock genes cause activation of the human PAI-1 gene promoter with 4G/5G allelic preference.

21 January 2018

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Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice

21 January 2018

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The effect of melatonin on bleomycin-induced pulmonary fibrosis in rats

21 January 2018

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Effectiveness of a treatment based on melatonin in five patients with systemic sclerosis

21 January 2018

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TIMP-1, -2, -3, and -4 in idiopathic pulmonary fibrosis. A prevailing nondegradative lung microenvironment?

21 January 2018

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12 December 2020

Acidic fibroblast growth factor induces an antifibrogenic phenotype in human lung fibroblasts

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Alveolar epithelial cell disintegrity and subsequent activation: a key process in pulmonary fibrosis

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12 December 2020

Sirt1 regulates canonical TGF-β signalling to control fibroblast activation and tissue fibrosis

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Radiation-induced lung injury in vivo: expression of transforming growth factor-beta precedes fibrosis

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TGF-beta1 stimulates production of gelatinase (MMP-9), collagenases (MMP-1, -13) and stromelysins (MMP-3, -10, -11) by human corneal epithelial cells

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Lung cytokine production in bleomycin-induced pulmonary fibrosis

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12 December 2020

Alterations in pulmonary mRNA encoding procollagens, fibronectin and transforming growth factor-beta precede bleomycin-induced pulmonary fibrosis in mice

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12 December 2020

Effect of melatonin on normal and sclerodermic skin fibroblast proliferation

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12 December 2020

10.1186/S12931-016-0320-0

Identifiers

DOI

1 reference

Dimensions Publication ID

29 July 2017

1 reference

https://scigraph.springernature.com/pub.10.1186/s12931-016-0320-0

9 September 2019

1 reference

29 July 2017

1 reference