(Q37666378)

English

The circadian clock regulates rhythmic activation of the NRF2/glutathione-mediated antioxidant defense pathway to modulate pulmonary fibrosis.

scientific article published on March 2014

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24637114%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

The circadian clock regulates rhythmic activation of the NRF2/glutathione-mediated antioxidant defense pathway to modulate pulmonary fibrosis (English)

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10 March 2020

circadian rhythm

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pulmonary fibrosis

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Vanja Pekovic-Vaughan

1

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10 March 2020

2

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10 March 2020

David A. Bechtold

9

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10 March 2020

10

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10 March 2020

Gijsbertus van der Horst

13

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10 March 2020

15

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10 March 2020

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Hikari Yoshitane

3

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10 March 2020

Nan Yang

4

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10 March 2020

Dharshika Pathiranage

5

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10 March 2020

Baoqiang Guo

6

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10 March 2020

Aya Sagami

7

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10 March 2020

Keiko Taguchi

8

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10 March 2020

Masayuki Yamamoto

11

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10 March 2020

Jefferson Chan

12

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10 March 2020

Yoshitaka Fukada

14

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10 March 2020

publication date

1 March 2014

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10 March 2020

Genes & Development

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10 March 2020

28

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10 March 2020

6

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10 March 2020

548-560

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10 March 2020

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3967045/fullTextXML

based on heuristic

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Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration.

1 reference

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6 September 2017

Transcriptional control of antioxidant defense by the circadian clock

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967045

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Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice

1 reference

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1 reference

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6 September 2017

Regulation of circadian clocks by redox homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967045

6 September 2017

Bmal1 and β-cell clock are required for adaptation to circadian disruption, and their loss of function leads to oxidative stress-induced β-cell failure in mice

1 reference

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6 September 2017

Circadian regulation of glutathione levels and biosynthesis in Drosophila melanogaster

1 reference

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1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967045

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Diurnal variation of hepatic antioxidant gene expression in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967045

6 September 2017

Circadian rhythm of redox state regulates excitability in suprachiasmatic nucleus neurons

1 reference

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6 September 2017

Brain and muscle Arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967045

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Peroxiredoxins are conserved markers of circadian rhythms

1 reference

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Circadian clock protein BMAL1 regulates cellular senescence in vivo

1 reference

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6 September 2017

Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients

1 reference

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Conserved cysteine residues in the mammalian lamin A tail are essential for cellular responses to ROS generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967045

6 September 2017

Genome-wide and phase-specific DNA-binding rhythms of BMAL1 control circadian output functions in mouse liver

1 reference

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6 September 2017

Circadian rhythms persist without transcription in a eukaryote

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967045

6 September 2017

Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis

1 reference

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6 September 2017

Discovery of the negative regulator of Nrf2, Keap1: a historical overview

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967045

6 September 2017

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967045

6 September 2017

Oxidative stress and glutathione in TGF-beta-mediated fibrogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967045

6 September 2017

Direct interaction between Nrf2 and p21(Cip1/WAF1) upregulates the Nrf2-mediated antioxidant response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967045

6 September 2017

Roles of CLOCK phosphorylation in suppression of E-box-dependent transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967045

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NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer

1 reference

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The Nrf2-antioxidant response element signaling pathway and its activation by oxidative stress

1 reference

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6 September 2017

Ligand modulation of REV-ERBalpha function resets the peripheral circadian clock in a phasic manner

1 reference

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Circadian regulation of response to oxidative stress in Drosophila melanogaster

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

1 reference

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Simple method of estimating severity of pulmonary fibrosis on a numerical scale

1 reference

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6 September 2017

Nrf2 protects against pulmonary fibrosis by regulating the lung oxidant level and Th1/Th2 balance

1 reference

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1 reference

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1 reference

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1 reference

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1 September 2018

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1 reference

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1 September 2018

Genetic dissection of the Nrf2-dependent redox signaling-regulated transcriptional programs of cell proliferation and cytoprotection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967045

1 September 2018

The transcription factor NRF2 protects against pulmonary fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3967045

1 September 2018

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1 reference

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1 September 2018

Identifiers

10.1101/GAD.237081.113

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24637114%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24637114%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

PubMed publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24637114%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

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