(Q34032642)

30 July 2017

title

Conserved cysteine residues in the mammalian lamin A tail are essential for cellular responses to ROS generation (English)

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30 July 2017

author

Vanja Pekovic-Vaughan

Vanja Pekovic

1

0 references

Adam Benham

Adam M Benham

5

0 references

Robert Edwards

Robert Edwards

6

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Thomas von Zglinicki

Thomas von Zglinicki

8

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author name string

Ian Gibbs-Seymour

2

1 reference

30 July 2017

Ewa Markiewicz

3

1 reference

30 July 2017

Fahad Alzoghaibi

4

1 reference

30 July 2017

Manfred Wenhert

7

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30 July 2017

Christopher J Hutchison

9

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30 July 2017

publication date

1 December 2011

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30 July 2017

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30 July 2017

volume

10

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30 July 2017

issue

6

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30 July 2017

page(s)

1067-1079

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A DNA damage checkpoint response in telomere-initiated senescence

30 July 2017

cites work

1 reference

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The CXXCXXC motif determines the folding, structure and stability of human Ero1-Lalpha

21 January 2018

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Aging of Hutchinson-Gilford progeria syndrome fibroblasts is characterised by hyperproliferation and increased apoptosis

21 January 2018

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Nuclear lamins: laminopathies and their role in premature ageing.

21 January 2018

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Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors

21 January 2018

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Perturbation of wild-type lamin A metabolism results in a progeroid phenotype

21 January 2018

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A lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells

21 January 2018

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Quantitative AP-1 gene regulation by oxidative stress in the human retinal pigment epithelium.

21 January 2018

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Actin S-glutathionylation: evidence against a thiol-disulphide exchange mechanism

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

The broad spectrum of responses to oxidants in proliferating cells: a new paradigm for oxidative stress

21 January 2018

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Alterations in mitosis and cell cycle progression caused by a mutant lamin A known to accelerate human aging

21 January 2018

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Lamina-associated polypeptide 2alpha regulates cell cycle progression and differentiation via the retinoblastoma-E2F pathway.

21 January 2018

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21 January 2018

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Protein thiol oxidation in health and disease: techniques for measuring disulfides and related modifications in complex protein mixtures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Reversible cysteine-targeted oxidation of proteins during renal oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Identification of ROS using oxidized DCFDA and flow-cytometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Nuclear envelope defects cause stem cell dysfunction in premature-aging mice

21 January 2018

1 reference

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Oxidized protein degradation and repair in ageing and oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Fast regulation of AP-1 activity through interaction of lamin A/C, ERK1/2, and c-Fos at the nuclear envelope

21 January 2018

1 reference

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Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Antioxidant and prooxidant mechanisms in the regulation of redox(y)-sensitive transcription factors

21 January 2018

1 reference

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21 January 2018

1 reference

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Aging: a theory based on free radical and radiation chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

The role of the head and tail domain in lamin structure and assembly: analysis of bacterially expressed chicken lamin A and truncated B2 lamins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Accelerated telomere shortening and replicative senescence in human fibroblasts overexpressing mutant and wild-type lamin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

A-type lamins: guardians of the soma?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

A mechanism of AP-1 suppression through interaction of c-Fos with lamin A/C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

A-type lamins regulate retinoblastoma protein function by promoting subnuclear localization and preventing proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Aging: progeria and the lamin connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Not every disulfide lasts forever: disulfide bond formation as a redox switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Genomic instability in laminopathy-based premature aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

A novel interaction between lamin A and SREBP1: implications for partial lipodystrophy and other laminopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Lamin A/C binding protein LAP2alpha is required for nuclear anchorage of retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Molecular characterization of protein kinase C-alpha binding to lamin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Nuclear envelope alterations in fibroblasts from LGMD1B patients carrying nonsense Y259X heterozygous or homozygous mutation in lamin A/C gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Lamin A and ZMPSTE24 (FACE-1) defects cause nuclear disorganization and identify restrictive dermopathy as a lethal neonatal laminopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Adult stem cell maintenance and tissue regeneration in the ageing context: the role for A-type lamins as intrinsic modulators of ageing in adult stem cells and their niches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Nucleoplasmic LAP2alpha-lamin A complexes are required to maintain a proliferative state in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Transcriptional repression mediated by repositioning of genes to the nuclear lamina

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Farnesylated lamins, progeroid syndromes and farnesyl transferase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Mouse models of the laminopathies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Nuclear lamins: their structure, assembly, and interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Identification of 12-lipoxygenase interaction with cellular proteins by yeast two-hybrid screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Accumulation of multiple forms of lamin A with down-regulation of FACE-1 suppresses growth in senescent human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Lamin B1 is required for mouse development and nuclear integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

"Laminopathies": a wide spectrum of human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

Human cell senescence as a DNA damage response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1474-9726.2011.00750.X

10.1111/J.1474-9726.2011.00750.X

21 January 2018

Identifiers

DOI

1 reference

release_lii6ltmcnrbjtnhczf6mjpclea

30 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/lii6ltmcnrbjtnhczf6mjpclea

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference