(Q34106524)

31 July 2017

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title

Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes (English)

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31 July 2017

Toussaint O

1

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31 July 2017

Medrano EE

series ordinal

2

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31 July 2017

von Zglinicki T

series ordinal

3

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31 July 2017

language of work or name

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1 October 2000

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31 July 2017

Experimental Gerontology

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31 July 2017

35

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31 July 2017

927-945

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31 July 2017

8

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Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

31 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Oxygen modulates growth of human cells at physiologic partial pressures

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Melanin accumulation accelerates melanocyte senescence by a mechanism involving p16INK4a/CDK4/pRB and E2F1

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Different mechanisms of tert-butyl hydroperoxide-induced lethal injury in normal and tumor thymocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

EMBO WORKSHOP REPORT: Molecular and cellular gerontology Serpiano, Switzerland, September 18-22, 1999.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

The telomere lengthening mechanism in telomerase-negative immortal human cells does not involve the telomerase RNA subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

tert-butyl hydroperoxide induced [Ca2+]i increase in thymus and thymoma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Defending genome integrity during DNA replication: a proposed role for RecQ family helicases

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Oxidative DNA damage and senescence of human diploid fibroblast cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Replicative senescence and oxidant-induced premature senescence. Beyond the control of cell cycle checkpoints

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Molecular analysis of H2O2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Irreversibility of cellular aging and neoplastic transformation: a clonal analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Interaction between Set1p and checkpoint protein Mec3p in DNA repair and telomere functions.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Relationship between donor age and the replicative lifespan of human cells in culture: a reevaluation

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

p16 INK4a can initiate an autonomous senescence program

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblast

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Appearance of biomarkers of in vitro ageing after successive stimulation of WI-38 fibroblasts with IL-1alpha and TNF-alpha: senescence associated beta-galactosidase activity and morphotype transition

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Quantification of wild-type mitochondrial DNA and its 4.8-kb deletion in rat organs

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Age-dependent telomere shortening is slowed down by enrichment of intracellular vitamin C via suppression of oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Senescence of cultured human fibroblasts: mitotic versus metabolic time.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

The Werner syndrome protein is a DNA helicase

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Mammalian telomeres end in a large duplex loop

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Activation of a cAMP pathway and induction of melanogenesis correlate with association of p16(INK4) and p27(KIP1) to CDKs, loss of E2F-binding activity, and premature senescence of human melanocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Telomere loss: mitotic clock or genetic time bomb?

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

The serial cultivation of human diploid cell strains

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

1 reference

7 January 2021

Toward a biological understanding of the ageing process

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Shortening of the in vitro lifespan of human diploid fibroblasts exposed to hyperbaric oxygen.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Effect of oxygen on the growth of human epidermal keratinocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Effects of oxygen tension on the growth and pigmentation of normal human melanocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Signals from the reproductive system regulate the lifespan of C. elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Intramitotic variation in proliferative potential: stochastic events in cellular aging

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Functional interaction between the Werner Syndrome protein and DNA polymerase delta

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Increased cytotoxicity of chronic hypoxic cells by molecular inhibition of GRP78 induction

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Haemin enhancement of glucose transport in human lymphocytes: stimulation of protein tyrosine phosphatase and activation of p56lck tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

The 170-kDa glucose-regulated stress protein is an endoplasmic reticulum protein that binds immunoglobulin

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Cataloging altered gene expression in young and senescent cells using enhanced differential display

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Accumulation of short telomeres in human fibroblasts prior to replicative senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Comparative study of oxygen toxicity in human fibroblasts and endothelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Linking histone acetylation to transcriptional regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Slowing down aging of cultured embryonal chick chondrocytes by maintenance under lowered oxygen tension

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to t-butylhydroperoxide

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Position effect of human telomeric repeats on replication timing

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Human skin mitochondrial DNA deletions associated with light exposure.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Regulation of glucose uptake by stressed cells

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Genetic analysis of indefinite division in human cells: identification of four complementation groups

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Preferential accumulation of single-stranded regions in telomeres of human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Importance of various antioxidant enzymes for cell stability. Confrontation between theoretical and experimental data

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Low levels of reactive oxygen species as modulators of cell function

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Differential degradation of intracellular proteins in human skin fibroblasts of mitotic and mitomycin-C (MMC)-induced postmitotic differentiation states in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Selective enrichment and biochemical characterization of seven human skin fibroblasts cell types in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Telomere shortening triggers a p53-dependent cell cycle arrest via accumulation of G-rich single stranded DNA fragments.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Telomere length as a marker of oxidative stress in primary human fibroblast cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Is beta-galactosidase staining a marker of senescence in vitro and in vivo?

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Microarray analysis of replicative senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Accelerated telomere shortening in fibroblasts after extended periods of confluency.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Intraclonal variation in proliferative potential of human diploid fibroblasts: stochastic mechanism for cellular aging

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Oxidative stress, caloric restriction, and aging

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Different kinetics of senescence in human fibroblasts and peritoneal mesothelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Aging as a multi-step process characterized by a lowering of entropy production leading the cell to a sequence of defined stages. II. Testing some predictions on aging human fibroblasts in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Effects of modulations of the energetic metabolism on the mortality of cultured cells

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Cellular aging and the importance of energetic factors

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Aging as a multi-step process characterized by a lowering of entropy production leading the cell to a sequence of defined stages

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

From telomere loss to p53 induction and activation of a DNA-damage pathway at senescence: the telomere loss/DNA damage model of cell aging

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Role of oxidative stress in telomere length regulation and replicative senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Mild Hyperoxia Shortens Telomeres and Inhibits Proliferation of Fibroblasts: A Model for Senescence?

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Induction of glucose regulated protein (grp78) and inducible heat shock protein (hsp70) mRNAs in rat brain after kainic acid seizures and focal ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Posttranslational modifications of p53 in replicative senescence overlapping but distinct from those induced by DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

The ubiquitous glucose transporter GLUT-1 belongs to the glucose-regulated protein family of stress-inducible proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Telomeres: beginning to understand the end.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

Senescence of human fibroblasts induced by oncogenic Raf.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2800%2900180-7

7 January 2021

10.1016/S0531-5565(00)00180-7

Identifiers

DOI

1 reference

release_l2btoeskwvbgdivhfhidufktby

31 July 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/l2btoeskwvbgdivhfhidufktby

24 November 2022

mapped directly with Wikidata item

1 reference