(Q40715420)

English

Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis

scientific article published on 24 July 2002

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Expression of human telomerase (hTERT) does not prevent stress-induced senescence in normal human fibroblasts but protects the cells from stress-induced apoptosis and necrosis (English)

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

author name string

Vera Gorbunova

1

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Andrei Seluanov

2

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Olivia M Pereira-Smith

3

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

language of work or name

0 references

publication date

24 July 2002

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

277

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

41

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

38540-38549

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Molecular aspects of the relationship between cancer and aging: tumor suppressor activity during cellular senescence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Regulation of cellular senescence by p53.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Telomeres and telomerase: implications for cancer and aging

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Stress, DNA damage and ageing -- an integrative approach

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Extension of life-span by introduction of telomerase into normal human cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Induction of a senescence-like phenotype in bovine aortic endothelial cells by ionizing radiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Molecular analysis of H2O2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Induction of replicative senescence biomarkers by sublethal oxidative stresses in normal human fibroblast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Similar gene expression pattern in senescent and hyperoxic-treated fibroblasts.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Uncoupling the senescent phenotype from telomere shortening in hydrogen peroxide-treated fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Absence of cancer-associated changes in human fibroblasts immortalized with telomerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Emerging roles for telomerase in regulating cell differentiation and survival: a neuroscientist's perspective

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

hTERT can function with rabbit telomerase RNA: regulation of gene expression and attenuation of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Human endothelial cell life extension by telomerase expression

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Role of p14(ARF) in replicative and induced senescence of human fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

22 Autoradiography

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Change of the death pathway in senescent human fibroblasts in response to DNA damage is caused by an inability to stabilize p53.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Cellular responses to DNA damage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Cell cycle regulation in H(2)O(2)-induced premature senescence of human diploid fibroblasts and regulatory control exerted by the papilloma virus E6 and E7 proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Senescence-like changes induced by hydroxyurea in human diploid fibroblasts

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Stringent sequence requirements for the formation of human telomeres

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Chromosome healing: spontaneous and programmed de novo telomere formation by telomerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Chromosome healing, telomere capture and mechanisms of radiation-induced chromosome breakage

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Genetic analysis of indefinite division in human cells: identification of four complementation groups

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Senescence of human fibroblasts induced by oncogenic Raf.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Telomere shortening and apoptosis in telomerase-inhibited human tumor cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Cellular sites of H2O2-induced damage and their protection by nitroxides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Apoptosis induced by exposure to a low steady-state concentration of H2O2 is a consequence of lysosomal rupture

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Hydrogen peroxide-induced apoptosis and necrosis in human lung fibroblasts: protective roles of glutathione

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Telomerase primer specificity and chromosome healing

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202671200

21 January 2018

Identifiers

10.1074/JBC.M202671200

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

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