(Q33818655)

29 July 2017

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title

Serine/threonine phosphorylation in cytokine signal transduction (English)

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29 July 2017

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McCubrey JA

1

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29 July 2017

May WS

series ordinal

2

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29 July 2017

Duronio V

series ordinal

3

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29 July 2017

Mufson A

series ordinal

4

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29 July 2017

publication date

1 January 2000

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29 July 2017

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29 July 2017

volume

14

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29 July 2017

issue

1

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29 July 2017

page(s)

9-21

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

29 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Tyrosine phosphorylation of DNA binding proteins by multiple cytokines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Protein tyrosine phosphorylation as a mechanism which regulates cytokine activation of early response genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Induction of early response genes by interferons, interleukins, and growth factors by the tyrosine phosphorylation of latent transcription factors. Implications for chronic inflammatory diseases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Regulation of the Jak/STAT signalling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Downstream signalling events regulated by phosphatidylinositol 3-kinase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Interleukin-3 induces association of the protein-tyrosine phosphatase SHP2 and phosphatidylinositol 3-kinase with a 100-kDa tyrosine-phosphorylated protein in hemopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Phosphorylation of Cbl following stimulation with interleukin-3 and its association with Grb2, Fyn, and phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Phosphoinositide 3-kinases: a conserved family of signal transducers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

The modular phosphorylation and activation of p70s6k.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Mechanisms and consequences of activation of protein kinase B/Akt

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvement of MEK upstream of Bad phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Phosphatidylinositol 3-OH kinase activity is not required for activation of mitogen-activated protein kinase by cytokines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Regulation of bad phosphorylation and association with Bcl-x(L) by the MAPK/Erk kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Role of phosphatidylinositol 3-OH-kinase activity in the inhibition of apoptosis in haemopoietic cells: phosphatidylinositol 3-OH-kinase inhibitors reveal a difference in signalling between interleukin-3 and granulocyte-macrophage colony stimulating

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Dissociation of apoptosis from proliferation, protein kinase B activation, and BAD phosphorylation in interleukin-3-mediated phosphoinositide 3-kinase signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Role of phosphoinositide 3-kinase in activation of ras and mitogen-activated protein kinase by epidermal growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

A phosphatidylinositol 3-kinase-dependent pathway that differentially regulates c-Raf and A-Raf

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Targeted disruption of SHIP leads to Steel factor-induced degranulation of mast cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Requirement for MAP kinase (ERK2) activity in interferon alpha- and interferon beta-stimulated gene expression through STAT proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Interferon gamma activation of Raf-1 is Jak1-dependent and p21ras-independent

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Beta interferon and oncostatin M activate Raf-1 and mitogen-activated protein kinase through a JAK1-dependent pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Endothelial apoptosis in Braf-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Craf-1 protein kinase is essential for mouse development.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoprotein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Src kinases and not JAKs activate STATs during IL-3 induced myeloid cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Repression of Stat3 activity by activation of mitogen-activated protein kinase (MAPK)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Activation of Raf-1 by interferon gamma and oncostatin M requires expression of the Stat1 transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Differential effects of retroviral long terminal repeats on interleukin-3 gene expression and autocrine transformation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells: possible sites for intervention with anti-neoplastic drugs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Post-natal lethality and neurological and gastrointestinal defects in mice with targeted disruption of the A-Raf protein kinase gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Conditionally oncogenic forms of the A-Raf and B-Raf protein kinases display different biological and biochemical properties in NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Cooperating oncogenes converge to regulate cyclin/cdk complexes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Differential activation of ERK and JNK mitogen-activated protein kinases by Raf-1 and MEKK

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

MEKK1 phosphorylates MEK1 and MEK2 but does not cause activation of mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Mammalian mitogen-activated protein kinase pathways are regulated through formation of specific kinase-activator complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Cellular stresses and cytokines activate multiple mitogen-activated-protein kinase kinase homologues in PC12 and KB cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Ras-dependent growth factor regulation of MEK kinase in PC12 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP Kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Signal transduction pathways involving the Raf proto-oncogene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Specific activation of p85-p110 phosphatidylinositol 3'-kinase stimulates DNA synthesis by ras- and p70 S6 kinase-dependent pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Phosphatidylinositol 3' kinase: one of the effectors of Ras.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Cell cycle regulation of p70 S6 kinase and p42/p44 mitogen-activated protein kinases in Swiss mouse 3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Evidence for MEK-independent pathways regulating the prolonged activation of the ERK-MAP kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Oncogenic Raf-1 activates p70 S6 kinase via a mitogen-activated protein kinase-independent pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Aggregation of the FcepsilonRI on mast cells stimulates c-Jun amino-terminal kinase activity. A response inhibited by wortmannin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Activation of 70-kDa S6 kinase, induced by the cytokines interleukin-3 and erythropoietin and inhibited by rapamycin, is not an absolute requirement for cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

TOR signalling and control of cell growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Cyclosporin A, FK-506, and rapamycin: pharmacologic probes of lymphocyte signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Rho family proteins and Ras transformation: the RHOad less traveled gets congested.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Differential properties of D4/LyGDI versus RhoGDI: phosphorylation and rho GTPase selectivity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Overexpression of protein kinase C betaII induces colonic hyperproliferation and increased sensitivity to colon carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Effect of dietary fat on colonic protein kinase C and induction of aberrant crypt foci

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

The role of serine/threonine phosphorylation in hematopoietic cytokine receptor signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

A phosphatidylcholine phospholipase C inhibitor, D609, blocks interleukin-3 (IL-3)-induced bcl-2 expression but not c-myc expression in human IL-3-dependent cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Transcriptional activation of egr-1 by granulocyte-macrophage colony-stimulating factor but not interleukin 3 requires phosphorylation of cAMP response element-binding protein (CREB) on serine 133

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Granulocyte-macrophage colony-stimulating factor induces the transcriptional activation of egr-1 through a protein kinase A-independent signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Granulocyte-macrophage colony-stimulating factor and interleukin-3 signaling pathways converge on the CREB-binding site in the human egr-1 promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Fludarabine-induced immunosuppression is associated with inhibition of STAT1 signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Interleukin 2 signaling involves the phosphorylation of Stat proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Signal transducer and activator of transcription-3 (STAT3) is constitutively activated in normal, self-renewing B-1 cells but only inducibly expressed in conventional B lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

B lymphocytes from patients with chronic lymphocytic leukemia contain signal transducer and activator of transcription (STAT) 1 and STAT3 constitutively phosphorylated on serine residues.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

T cell-mediated pathology in two models of experimental colitis depends predominantly on the interleukin 12/Signal transducer and activator of transcription (Stat)-4 pathway, but is not conditional on interferon gamma expression by T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Jak2 is essential for signaling through a variety of cytokine receptors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Differential control of the phosphorylation state of proline-juxtaposed serine residues Ser725 of Stat5a and Ser730 of Stat5b in prolactin-sensitive cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Prolactin stimulates serine/tyrosine phosphorylation and formation of heterocomplexes of multiple Stat5 isoforms in Nb2 lymphocytes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Two Discrete Regions of Interleukin-2 (IL2) Receptor β Independently Mediate IL2 Activation of a PD98059/Rapamycin/Wortmannin-insensitive Stat5a/b Serine Kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

A human peptidyl-prolyl isomerase essential for regulation of mitosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Function of WW domains as phosphoserine- or phosphothreonine-binding modules

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Sequence-specific and phosphorylation-dependent proline isomerization: a potential mitotic regulatory mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Characterization and cell cycle regulation of the related human telomeric proteins Pin2 and TRF1 suggest a role in mitosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Bcl-2 targets the protein kinase Raf-1 to mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Apoptosis meets signal transduction: elimination of a BAD influence

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Bcl-2 phosphorylation required for anti-apoptosis function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

A functional role for mitochondrial protein kinase Calpha in Bcl2 phosphorylation and suppression of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Reversible phosphorylation of Bcl2 following interleukin 3 or bryostatin 1 is mediated by direct interaction with protein phosphatase 2A

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Screening of a library of phage-displayed peptides identifies human bcl-2 as a taxol-binding protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Mitogen-activated protein kinase pathway is dispensable for microtubule-active drug-induced Raf-1/Bcl-2 phosphorylation and apoptosis in leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Inactivation of Bcl-2 by phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401657

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2401657

1 reference

Dimensions Publication ID

29 July 2017

1018176267

0 references

1 reference