(Q33819434)

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Mutations in signal transduction proteins increase stress resistance and longevity in yeast, nematodes, fruit flies, and mammalian neuronal cells

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scholarly article

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Europe PubMed Central

29 July 2017

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Europe PubMed Central

Mutations in signal transduction proteins increase stress resistance and longevity in yeast, nematodes, fruit flies, and mammalian neuronal cells (English)

1 reference

Europe PubMed Central

29 July 2017

Catalase Dmel_CG6871

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GOA release 2020-03-11

author name string

Longo VD

1

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Europe PubMed Central

29 July 2017

publication date

1 September 1999

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Europe PubMed Central

29 July 2017

Neurobiology of Aging

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Europe PubMed Central

29 July 2017

20

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Europe PubMed Central

29 July 2017

479-486

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Europe PubMed Central

29 July 2017

5

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Europe PubMed Central

29 July 2017

Mitochondrial decay in aging

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Passage through stationary phase advances replicative aging in Saccharomyces cerevisiae

1 reference

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Fas- or ceramide-induced apoptosis is mediated by a Rac1-regulated activation of Jun N-terminal kinase/p38 kinases and GADD153

1 reference

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Germination conditions that require mitochondrial function in Saccharomyces cerevisiae: utilization of acetate and galactose

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Genetics of aging

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Stationary-phase regulation of the Saccharomyces cerevisiae SOD2 gene is dependent on additive effects of HAP2/3/4/5- and STRE-binding elements

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Life with 6000 genes

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Dual role of Ras and Rho proteins: at the cutting edge of life and death.

1 reference

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7 January 2021

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Nuclear localization of the C2H2 zinc finger protein Msn2p is regulated by stress and protein kinase A activity

1 reference

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7 January 2021

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Glucose induces cAMP-independent growth-related changes in stationary-phase cells of Saccharomyces cerevisiae

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Do changes in chromosomes cause aging?

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The cellular functions of small GTP-binding proteins

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Induction of cell death by stimulation of protein kinase C in human epithelial cells expressing a mutant ras oncogene: a potential therapeutic target

1 reference

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Vascular system defects and neuronal apoptosis in mice lacking ras GTPase-activating protein

1 reference

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7 January 2021

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Superoxide-mediated cytotoxicity in superoxide dismutase-deficient fetal fibroblasts

1 reference

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7 January 2021

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Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts

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Longevity, genes, and aging

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Increased life-span of age-1 mutants in Caenorhabditis elegans and lower Gompertz rate of aging

1 reference

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7 January 2021

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Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

1 reference

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7 January 2021

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Genetic analysis of yeast RAS1 and RAS2 genes.

1 reference

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7 January 2021

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Mutation in the silencing gene S/R4 can delay aging in S. cerevisiae

1 reference

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7 January 2021

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A C. elegans mutant that lives twice as long as wild type

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daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

1 reference

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Aging and resistance to oxidative damage in Caenorhabditis elegans

1 reference

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7 January 2021

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Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

1 reference

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7 January 2021

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Extended life-span and stress resistance in the Drosophila mutant methuselah

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Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress

1 reference

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Human Bcl-2 reverses survival defects in yeast lacking superoxide dismutase and delays death of wild-type yeast

1 reference

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7 January 2021

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Superoxide dismutase activity is essential for stationary phase survival in Saccharomyces cerevisiae. Mitochondrial production of toxic oxygen species in vivo

1 reference

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7 January 2021

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Mitochondrial superoxide decreases yeast survival in stationary phase

1 reference

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7 January 2021

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Oxygen stress: a regulator of apoptosis in yeast

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7 January 2021

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PKB/Akt: connecting phosphoinositide 3-kinase to cell survival and beyond

1 reference

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Genetic analysis of ageing: role of oxidative damage and environmental stresses.

1 reference

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7 January 2021

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The Mitochondrial F0F1-ATPase proton pump is required for function of the proapoptotic protein Bax in yeast and mammalian cells.

1 reference

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Mitochondrial disease in superoxide dismutase 2 mutant mice

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Nerve growth factor treatment prevents the increase in superoxide produced by epidermal growth factor in PC12 cells

1 reference

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Requirement of Saccharomyces cerevisiae Ras for completion of mitosis

1 reference

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A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

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Life span of individual yeast cells

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Ras2 signals via the Cdc42/Ste20/mitogen-activated protein kinase module to induce filamentous growth in Saccharomyces cerevisiae

1 reference

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Active p21Ras is sufficient for rescue of NGF-dependent rat sympathetic neurons

1 reference

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7 January 2021

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Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster.

1 reference

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Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons.

1 reference

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7 January 2021

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14-3-3 proteins are essential for RAS/MAPK cascade signaling during pseudohyphal development in S. cerevisiae

1 reference

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7 January 2021

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NF-kappaB mediates alphavbeta3 integrin-induced endothelial cell survival

1 reference

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7 January 2021

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The HOG pathway controls osmotic regulation of transcription via the stress response element (STRE) of the Saccharomyces cerevisiae CTT1 gene.

1 reference

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7 January 2021

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Longevity and the genetic determination of collagen glycoxidation kinetics in mammalian senescence

1 reference

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Death-defying yeast identify novel apoptosis genes

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AGING INSACCHAROMYCES CEREVISIAE

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7 January 2021

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Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants

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7 January 2021

based on heuristic

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Yeast PKA represses Msn2p/Msn4p-dependent gene expression to regulate growth, stress response and glycogen accumulation

1 reference

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7 January 2021

based on heuristic

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Enhancement of peroxynitrite-induced apoptosis in PC12 cells by fibroblast growth factor-1 and nerve growth factor requires p21Ras activation and is suppressed by Bcl-2.

1 reference

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FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies

1 reference

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RAS2 of Saccharomyces cerevisiae is required for gluconeogenic growth and proper response to nutrient limitation

1 reference

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7 January 2021

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Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase

1 reference

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7 January 2021

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In yeast, RAS proteins are controlling elements of adenylate cyclase.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Oxidative stress and ageing in Caenorhabditis elegans

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Biodemographic trajectories of longevity

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7 January 2021

based on heuristic

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Stationary phase in Saccharomyces cerevisiae

1 reference

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7 January 2021

based on heuristic

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Genome sequencing. Europeans move on from yeast to TB

1 reference

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7 January 2021

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JNK, but not MAPK, activation is associated with Fas-mediated apoptosis in human T cells

1 reference

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7 January 2021

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Identifiers

10.1016/S0197-4580(99)00089-5

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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