(Q47996690)

7 February 2018

review article

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title

Dual role of Ras and Rho proteins: at the cutting edge of life and death (English)

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7 February 2018

author name string

Gómez J

1

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7 February 2018

Martínez-A C

2

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7 February 2018

González A

3

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7 February 2018

Rebollo A

4

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7 February 2018

publication date

1 April 1998

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7 February 2018

Immunology & Cell Biology

published in

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7 February 2018

volume

76

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7 February 2018

issue

2

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7 February 2018

page(s)

125-134

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7 February 2018

The genetic regulation of apoptosis

cites work

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

21 January 2018

Regulators of cell death

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

What is the restriction point?

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

An immunologist's look at the Rho and Rab GTP-binding proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Proteins regulating Ras and its relatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

The GTPase superfamily: a conserved switch for diverse cell functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Regulators and Effectors of ras Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

The many roads that lead to Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Sequence requirement for peptide recognition by rat brain p21ras protein farnesyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Activation of mitogen-activated protein kinase kinase by v-Raf in NIH 3T3 cells and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

The stress-activated protein kinase subfamily of c-Jun kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Transcriptional regulation by extracellular signals: mechanisms and specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Signaling through the hematopoietic cytokine receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Phosphatidylinositol-3-OH kinase as a direct target of Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

A human protein selected for interference with Ras function interacts directly with Ras and competes with Raf1

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Direct interaction between Ras and the kinase domain of mitogen-activated protein kinase kinase kinase (MEKK1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

KSR, a novel protein kinase required for RAS signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Kinase suppressor of Ras is ceramide-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

The protein kinase KSR interacts with 14-3-3 protein and Raf.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

JNK is involved in signal integration during costimulation of T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Ras activation leads to cell proliferation or apoptotic cell death upon interleukin-2 stimulation or lymphokine deprivation, respectively

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

p190-B, a new member of the Rho GAP family, and Rho are induced to cluster after integrin cross-linking

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

An X chromosome-linked gene encoding a protein with characteristics of a rhoGAP predominantly expressed in hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Inhibition of receptor signaling to phospholipase D by Clostridium difficile toxin B. Role of Rho proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Identification of a putative target for Rho as the serine-threonine kinase protein kinase N

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Protein kinase N (PKN) and PKN-related protein rhophilin as targets of small GTPase Rho

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

A novel serine/threonine kinase binding the Ras-related RhoA GTPase which translocates the kinase to peripheral membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Formation of actin stress fibers and focal adhesions enhanced by Rho-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Cellular ras activity is required for passage through multiple points of the G0/G1 phase in BALB/c 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Cdc25 cell-cycle phosphatase as a target of c-myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Cooperating oncogenes converge to regulate cyclin/cdk complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Cell cycle: routine role for Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Raf1 interaction with Cdc25 phosphatase ties mitogenic signal transduction to cell cycle activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Cell cycle-dependent activation of Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Identification of residues critical for Ras(17N) growth-inhibitory phenotype and for Ras interaction with guanine nucleotide exchange factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Effect of a dominant inhibitory Ha-ras mutation on neuronal differentiation of PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

p21ras activation via hemopoietin receptors and c-kit requires tyrosine kinase activity but not tyrosine phosphorylation of p21ras GTPase-activating protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

An essential role for Rac in Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

A role for Rho in Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Ras activation is necessary for integrin-mediated activation of extracellular signal-regulated kinase 2 and cytosolic phospholipase A2 but not for cytoskeletal organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Orientation and three-dimensional organization of actin filaments in dividing cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Signal transduction from the extracellular matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

21 January 2018

F-actin capping proteins

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

LPA: a novel lipid mediator with diverse biological actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Expression cloning of oncogenes by retroviral transfer of cDNA libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Direct involvement of the small GTP-binding protein Rho in lbc oncogene function

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

The small GTP-binding protein rho activates c-Jun N-terminal kinases/stress-activated protein kinases in human kidney 293T cells. Evidence for a Pak-independent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

A domain containing the Cdc42/Rac interactive binding (CRIB) region of p65PAK inhibits transcriptional activation and cell transformation mediated by the Ras-Rac pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Role of actin polymerization and adhesion to extracellular matrix in Rac- and Rho-induced cytoskeletal reorganization

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

JNK, but not MAPK, activation is associated with Fas-mediated apoptosis in human T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Vascular system defects and neuronal apoptosis in mice lacking ras GTPase-activating protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

R-Ras promotes apoptosis caused by growth factor deprivation via a Bcl-2 suppressible mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Phosphorylation of Bcl-2 protein and association with p21Ras in Ras-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Bcl-2 associates with the ras-related protein R-ras p23

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

The GTPase Rho has a critical regulatory role in thymus development

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Rho prevents apoptosis through Bcl-2 expression: implications for interleukin-2 receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor: possible link with the c-myc induction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Interleukin 2 regulates Raf-1 kinase activity through a tyrosine phosphorylation-dependent mechanism in a T-cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

The mitogenic response of T cells to interleukin-2 requires Raf-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Immediate-early genes induced by antigen receptor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Activation of the mitogen-activated protein kinase pathway induces transcription of the PAC-1 phosphatase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

Stimulation of p21 ras upon T-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.1998.00723.X

10.1046/J.1440-1711.1998.00723.X

21 January 2018

Identifiers

DOI

1 reference

7 February 2018

release_23cqheuakff5bj4et3u6rma3im

Fatcat ID

0 references

1 reference

7 February 2018