(Q33822190)

English

Intracellular pharmacokinetics of methotrexate polyglutamates in human breast cancer cells. Selective retention and less dissociable binding of 4-NH2-10-CH3-pteroylglutamate4 and 4-NH2-10-CH3-pteroylglutamate5 to dihydrofolate reductase

scientific article published on September 1, 1983

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scholarly article

1 reference

Europe PubMed Central

29 July 2017

Intracellular pharmacokinetics of methotrexate polyglutamates in human breast cancer cells. Selective retention and less dissociable binding of 4-NH2-10-CH3-pteroylglutamate4 and 4-NH2-10-CH3-pteroylglutamate5 to dihydrofolate reductase (English)

1 reference

Europe PubMed Central

29 July 2017

pharmacokinetics

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

J. Jolivet

1

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6193143

25 August 2023

B. A. Chabner

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6193143

25 August 2023

language of work or name

0 references

publication date

1 September 1983

1 reference

Europe PubMed Central

29 July 2017

full work available at URL

https://europepmc.org/articles/PMC1129242

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6193143

25 August 2023

https://europepmc.org/articles/PMC1129242?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A6193143

25 August 2023

http://www.jci.org/articles/view/111048/files/pdf

1 reference

10.1172/JCI111048

https://api.crossref.org/works/10.1172/JCI111048

25 August 2023

Journal of Clinical Investigation

1 reference

Europe PubMed Central

29 July 2017

72

1 reference

Europe PubMed Central

29 July 2017

773-778

1 reference

Europe PubMed Central

29 July 2017

3

1 reference

Europe PubMed Central

29 July 2017

Protein measurement with the Folin phenol reagent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1129242

4 July 2018

Enzymatic synthesis and function of folylpolyglutamates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1129242

4 July 2018

Synthesis, Retention, and Biological Activity of Methotrexate Polyglutamates in Cultured Human Breast Cancer Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1129242

4 July 2018

Methotrexate polyglutamate synthesis by cultured human breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1129242

4 July 2018

Polygammaglutamyl metabolites of methotrexate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1129242

4 July 2018

Tissue-specific synthesis of methotrexate polyglutamates in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1129242

4 July 2018

Establishment and characterization of three new continuous cell lines derived from human breast carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1129242

4 July 2018

Reactivation of dihydrofolate reductase inhibited by methotrexate or aminopterin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1129242

4 July 2018

Effect of methotrexate on dihydrofolate reductase activity in methotrexate-resistant human KB cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1129242

29 October 2018

The "induction" of leukocyte and erythrocyte dihydrofolate reductase by methotrexate. II. Clinical and pharmacologic studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/6193143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carrier-mediated Transport of the Folic Acid Analogue, Methotrexate, in the L1210 Leukemia Cell

1 reference

https://pubmed.ncbi.nlm.nih.gov/6193143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversibility of high-affinity binding of methotrexate in L1210 murine leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/6193143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged inhibition of DNA synthesis associated with the accumulation of methotrexate polyglutamates by cultured human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/6193143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human thymidylate synthetase--III. Effects of methotrexate and folate analogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/6193143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for the cytotoxic activity of polyglutamate derivatives of methotrexate

1 reference

https://pubmed.ncbi.nlm.nih.gov/6193143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular recovery of methotrexate-polyglutamates following efflux from L1210 leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/6193143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of methotrexate polyglutamates by bone marrow cells from patients with leukemia and lymphoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/6193143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recent concepts on the mechanism of action of methotrexate

1 reference

https://pubmed.ncbi.nlm.nih.gov/6193143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid formation of poly-gamma-glutamyl derivatives of methotrexate and their association with dihydrofolate reductase as assessed by high pressure liquid chromatography in the Ehrlich ascites tumor cell in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/6193143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of folinic acid on hepatoma cells containing methotrexate polyglutamates

1 reference

https://pubmed.ncbi.nlm.nih.gov/6193143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzymatic reduction of dihydrofolic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/6193143

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI111048

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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