(Q33825730)

29 July 2017

title

A p53-independent role for the MDM2 antagonist Nutlin-3 in DNA damage response initiation (English)

1 reference

29 July 2017

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Jane M Valentine

1

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29 July 2017

Sonia Kumar

series ordinal

2

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29 July 2017

Abdeladim Moumen

series ordinal

3

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29 July 2017

language of work or name

English

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publication date

21 February 2011

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29 July 2017

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29 July 2017

volume

11

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29 July 2017

page(s)

79

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2407-11-79

29 July 2017

exact match

0 references

cites work

ATM activates p53 by regulating MDM2 oligomerization and E3 processivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

DNA damage response to the Mdm2 inhibitor nutlin-3.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

Transient dephosphorylation of p53 serine 376 as an early response to ionizing radiation.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

Inhibition of Thr-55 phosphorylation restores p53 nuclear localization and sensitizes cancer cells to DNA damage

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

Phosphorylation of p53 on Ser15 during cell cycle caused by Topo I and Topo II inhibitors in relation to ATM and Chk2 activation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

p53 ubiquitination: Mdm2 and beyond

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

Rapid activation of ATR by ionizing radiation requires ATM and Mre11

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

DNA damage evaluated by gammaH2AX foci formation by a selective group of chemical/physical stressors

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

hnRNP K: an HDM2 target and transcriptional coactivator of p53 in response to DNA damage

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

P53 and prognosis: new insights and further complexity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

Phosphorylation of p53 on key serines is dispensable for transcriptional activation and apoptosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

H2AX: the histone guardian of the genome

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

Limited role of N-terminal phosphoserine residues in the activation of transcription by p53.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

Phosphorylation on Thr-55 by TAF1 mediates degradation of p53: a role for TAF1 in cell G1 progression

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

Cell cycle checkpoint signaling: cell cycle arrest versus apoptosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

Negative regulation of the mammalian UV response by Myc through association with Miz-1

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

p53 stabilization is decreased upon NFkappaB activation: a role for NFkappaB in acquisition of resistance to chemotherapy

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

Nuclear degradation of p53 occurs during down-regulation of the p53 response after DNA damage

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

Phosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damage

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

Critical role for Ser20 of human p53 in the negative regulation of p53 by Mdm2.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

p53 mutations in human cancers

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3050855

Mutations in serines 15 and 20 of human p53 impair its apoptotic activity.

4 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-79

Stabilization and activation of p53 downregulates mTOR signaling through AMPK in mantle cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-79

Functional integrity of the p53-mediated apoptotic pathway induced by the nongenotoxic agent nutlin-3 in B-cell chronic lymphocytic leukemia (B-CLL).

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-79

Characterization of Spo11-dependent and independent phospho-H2AX foci during meiotic prophase I in the male mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2407-11-79

p53 is preferentially recruited to the promoters of growth arrest genes p21 and GADD45 during replicative senescence of normal human fibroblasts

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21338495

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2407-11-79

1 reference

Dimensions Publication ID

29 July 2017

0 references

1 reference

29 July 2017

1 reference