(Q33828621)

29 July 2017

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title

Vitamin E and heart disease: basic science to clinical intervention trials (English)

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29 July 2017

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Pryor WA

1

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29 July 2017

publication date

1 January 2000

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Free Radical Biology and Medicine

29 July 2017

published in

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29 July 2017

volume

28

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29 July 2017

issue

1

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29 July 2017

page(s)

141-164

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Is vitamin E the only lipid-soluble, chain-breaking antioxidant in human blood plasma and erythrocyte membranes?

29 July 2017

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7 January 2021

d-alpha-tocopherol inhibition of vascular smooth muscle cell proliferation occurs at physiological concentrations, correlates with protein kinase C inhibition, and is independent of its antioxidant properties

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7 January 2021

alpha-Tocopherol specifically inactivates cellular protein kinase C alpha by changing its phosphorylation state

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7 January 2021

alpha-tocopherol inhibits the respiratory burst in human monocytes. Attenuation of p47(phox) membrane translocation and phosphorylation

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7 January 2021

A function for the vitamin E metabolite alpha-tocopherol quinone as an essential enzyme cofactor for the mitochondrial fatty acid desaturases

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7 January 2021

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7 January 2021

Micronutrients prevent cancer and delay aging

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7 January 2021

Endothelial and smooth muscle cells alter low density lipoprotein in vitro by free radical oxidation

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7 January 2021

Monocytes and neutrophils oxidize low density lipoprotein making it cytotoxic

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7 January 2021

Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids

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7 January 2021

Lipoproteins and atherogenesis. Current concepts

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7 January 2021

Intake of antioxidants among American cardiologists

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7 January 2021

Atherosclerosis: a hypothesis concerning the initiating steps in pathogenesis

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7 January 2021

Vitamin E deficiency and neurologic disease

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7 January 2021

Mitochondrial superoxide and hydrogen peroxide generation, protein oxidative damage, and longevity in different species of flies

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7 January 2021

DNA oxidative damage and life expectancy in houseflies

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7 January 2021

Oxidative damage and motor neurone disease difficulties in the measurement of protein carbonyls in human brain tissue

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7 January 2021

Vitamin E in the treatment of tardive dyskinesia: the possible involvement of free radical mechanisms

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7 January 2021

Effect of dietary vitamin E and selenium on susceptibility of brain regions to lipid peroxidation

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7 January 2021

Mechanisms of radical formation from reactions of ozone with target molecules in the lung

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7 January 2021

Oxidative chemistry of nitric oxide: the roles of superoxide, peroxynitrite, and carbon dioxide

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7 January 2021

Lewis A. Conner Memorial Lecture. Oxidative modification of LDL and atherogenesis

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7 January 2021

Role of vitamin E in preventing the oxidation of low-density lipoprotein.

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7 January 2021

The role of lipid peroxidation and antioxidants in oxidative modification of LDL.

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7 January 2021

Effect of dietary antioxidant combinations in humans. Protection of LDL by vitamin E but not by beta-carotene.

1 reference

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7 January 2021

Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: recognition by receptors for acetylated low density lipoproteins

1 reference

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7 January 2021

Endothelial cell-derived chemotactic activity for mouse peritoneal macrophages and the effects of modified forms of low density lipoprotein

1 reference

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7 January 2021

Oxidatively modified low density lipoproteins: a potential role in recruitment and retention of monocyte/macrophages during atherogenesis

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7 January 2021

Minimally modified low density lipoprotein is biologically active in vivo in mice

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7 January 2021

Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells

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7 January 2021

Effect of vitamin C and E supplementation on susceptibility of plasma lipoproteins to peroxidation induced by acute smoking

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7 January 2021

Antioxidants and Atherosclerotic Heart Disease

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7 January 2021

The influence of antioxidant nutrients on platelet function in healthy volunteers

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7 January 2021

Synthetic byproducts of tocopherol oxidation as inhibitors of platelet function

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Platelet function in type I diabetes: effects of supplementation with large doses of vitamin E

1 reference

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7 January 2021

Effects of antioxidant supplementation on platelet function: a randomized pair-matched, placebo-controlled, double-blind trial in men with low antioxidant status

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

alpha-Tocopherol protects against expression of adhesion molecules on neutrophils and endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Vitamin E plus aspirin compared with aspirin alone in patients with transient ischemic attacks

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Reduced oxidative susceptibility of LDL from patients participating in an intensive atherosclerosis treatment program

1 reference

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7 January 2021

Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)

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7 January 2021

Do vitamin E and fish oil protect against ischaemic heart disease?

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7 January 2021

Molecular basis of alpha-tocopherol control of smooth muscle cell proliferation

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7 January 2021

Effect of a single high-fat meal on endothelial function in healthy subjects

1 reference

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7 January 2021

Vitamin E and atherosclerosis

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7 January 2021

Macrophages, oxidised lipids and atherosclerosis

1 reference

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7 January 2021

Lipoprotein oxidation and lipoprotein-induced cytotoxicity

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7 January 2021

Modification of human serum low density lipoprotein by oxidation--characterization and pathophysiological implications

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7 January 2021

R,R,R-alpha-tocopherol potentiates prostacyclin release in human endothelial cells. Evidence for structural specificity of the tocopherol molecule

1 reference

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7 January 2021

Vitamin E potentiates arachidonate release and phospholipase A2 activity in rat heart myoblastic cells

1 reference

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7 January 2021

Alpha-tocopherol inhibits agonist-induced monocytic cell adhesion to cultured human endothelial cells

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7 January 2021

Antioxidants inhibit the expression of intercellular cell adhesion molecule-1 and vascular cell adhesion molecule-1 induced by oxidized LDL on human umbilical vein endothelial cells

1 reference

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7 January 2021

The pathogenesis of atherosclerosis: a perspective for the 1990s

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7 January 2021

alpha-Tocopherol enrichment of monocytes decreases agonist-induced adhesion to human endothelial cells

1 reference

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7 January 2021

Dietary l-arginine and α-tocopherol reduce vascular oxidative stress and preserve endothelial function in hypercholesterolemic rabbits via different mechanisms

1 reference

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7 January 2021

Antioxidant diet preserves endothelium-dependent vasodilatation in resistance arteries of hypercholesterolemic rabbits exposed to environmental tobacco smoke

1 reference

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7 January 2021

Primary endothelial dysfunction: atherosclerosis

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7 January 2021

Endothelial dysfunction in human disease

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7 January 2021

Vitamin E: a sensor and an information transducer of the cell oxidation state

1 reference

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7 January 2021

Inhibition of smooth muscle cell proliferation and protein kinase C activity by tocopherols and tocotrienols

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

alpha-tocopherol inhibits aggregation of human platelets by a protein kinase C-dependent mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Effects of dietary vitamin E on the biosynthesis of 5-lipoxygenase products by rat polymorphonuclear leukocytes (PMNL)

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Modulation of the endogenous leukotriene production by fish oil and vitamin E

1 reference

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7 January 2021

The effects of alpha tocopherol supplementation on monocyte function. Decreased lipid oxidation, interleukin 1 beta secretion, and monocyte adhesion to endothelium

1 reference

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7 January 2021

Vitamin E inhibits low-density lipoprotein-induced adhesion of monocytes to human aortic endothelial cells in vitro

1 reference

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7 January 2021

Peroxidative stress and in vitro ageing of endothelial cells increases the monocyte-endothelial cell adherence in a human in vitro system

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7 January 2021

Oxidative status of lipoproteins in coronary disease patients

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7 January 2021

7 beta-hydroperoxycholest-5-en-3 beta-ol, a component of human atherosclerotic lesions, is the primary cytotoxin of oxidized human low density lipoprotein

1 reference

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7 January 2021

Lipoprotein oxidation and progression of carotid atherosclerosis

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7 January 2021

Autoantibody against oxidised LDL and progression of carotid atherosclerosis

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7 January 2021

Demonstration of the presence of lipid peroxide-modified proteins in human atherosclerotic lesions using a novel lipid peroxide-modified anti-peptide antibody.

1 reference

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7 January 2021

The relationship of hydroxyeicosatetraenoic acids and F2-isoprostanes to plaque instability in human carotid atherosclerosis

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7 January 2021

Interaction of ascorbate and alpha-tocopherol in resealed human erythrocyte ghosts. Transmembrane electron transfer and protection from lipid peroxidation

1 reference

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7 January 2021

Direct observation of a free radical interaction between vitamin E and vitamin C

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7 January 2021

Ascorbic acid protects lipids in human plasma and low-density lipoprotein against oxidative damage

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7 January 2021

Interaction of Dietary Vitamin C and Vitamin E on Guinea Pig Immune Responses to Mitogens

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7 January 2021

Antioxidant vitamins and low-density-lipoprotein oxidation

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7 January 2021

Serum alpha-tocopherol status in the United States population: findings from the Third National Health and Nutrition Examination Survey

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7 January 2021

The antioxidant nutrients and disease prevention--what do we know and what do we need to find out?

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7 January 2021

Dietary vitamin E requirement for optimum immune responses in the rat

1 reference

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7 January 2021

Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. The Bogalusa Heart Study

1 reference

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7 January 2021

Prevalence and extent of atherosclerosis in adolescents and young adults: implications for prevention from the Pathobiological Determinants of Atherosclerosis in Youth Study

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7 January 2021

Supplementation with low doses of vitamin E protects LDL from lipid peroxidation in men and women.

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7 January 2021

The effect of alpha-tocopherol supplementation on LDL oxidation. A dose-response study

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7 January 2021

Safety of oral intake of vitamin E.

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7 January 2021

Tolerance and safety of vitamin E: A toxicological position report

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7 January 2021

Assessment of the safety of supplementation with different amounts of vitamin E in healthy older adults

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7 January 2021

Effect of vitamin E on the anticoagulant response to warfarin

1 reference

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7 January 2021

Effect of selenium and vitamin E on the development of experimental atherosclerosis in rabbits

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Dietary vitamin E and the attenuation of early lesion development in modified Watanabe rabbits

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Low-dose alpha-tocopherol improves and high-dose alpha-tocopherol worsens endothelial vasodilator function in cholesterol-fed rabbits.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Effect of dietary vitamin E on plasma lipids and atherogenesis in restricted ovulator chickens

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Improvement in the endothelium-dependent relaxation in hypercholesterolemic rabbits treated with vitamin E

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Commodity consumption and ischemic heart disease mortality, with special reference to dietary practices.

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Inverse correlation between plasma vitamin E and mortality from ischemic heart disease in cross-cultural epidemiology

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7 January 2021

Plasma levels of antioxidant vitamins in relation to ischemic heart disease and cancer

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7 January 2021

Plasma vitamins E and A inversely correlated to mortality from ischemic heart disease in cross-cultural epidemiology

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7 January 2021

Relationship of plasma level of vitamin C to mortality from ischemic heart disease

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Increased risk of cardiovascular disease at suboptimal plasma concentrations of essential antioxidants: an epidemiological update with special attention to carotene and vitamin C.

1 reference

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7 January 2021

Risk of angina pectoris and plasma concentrations of vitamins A, C, and E and carotene

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Low plasma vitamins E and C. Increased risk of angina in Scottish men.

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7 January 2021

Antioxidants in adipose tissue and risk of myocardial infarction: the EURAMIC Study

1 reference

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7 January 2021

Is oxidative stress causally linked to unstable angina pectoris? A study in 100 CAD patients and matched controls

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7 January 2021

Antioxidant vitamins and cardiovascular disease

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Vitamin E consumption and the risk of coronary disease in women

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Vitamin E consumption and the risk of coronary heart disease in men.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Prospective assessment of coronary heart disease risk factors: the NHANES I epidemiologic follow-up study (NHEFS) 16-year follow-up

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Dietary intake of fat, fiber and other nutrients is related to the use of vitamin and mineral supplements in the United States: the 1992 National Health Interview Survey

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Vitamin C intake and mortality among a sample of the United States population.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Vitamin E and vitamin C supplement use and risk of all-cause and coronary heart disease mortality in older persons: the Established Populations for Epidemiologic Studies of the Elderly

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Vitamin E and heart disease: a case study

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Antioxidant vitamin intake and coronary mortality in a longitudinal population study

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Dietary antioxidant vitamins and death from coronary heart disease in postmenopausal women

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Alcohol, fish, fibre and antioxidant vitamins intake do not explain population differences in coronary heart disease mortality.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Carotenoids, vitamins C and E, and mortality in an elderly population

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Validation of a dietary questionnaire with plasma carotenoid and alpha-tocopherol levels

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Poor plasma status of carotene and vitamin C is associated with higher mortality from ischemic heart disease and stroke: Basel Prospective Study

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Lack of an association between serum vitamin E and myocardial infarction in a population with high vitamin E levels.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Vitamin E deficiency in variant angina

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Serum antioxidants and myocardial infarction. Are low levels of carotenoids and alpha-tocopherol risk factors for myocardial infarction?

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Dietary intake, plasma levels of antioxidant vitamins, and oxidative stress in relation to coronary artery disease in elderly subjects

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7 January 2021

Usefulness of antioxidant vitamins in suspected acute myocardial infarction (the Indian experiment of infarct survival-3)

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7 January 2021

Serum selenium, vitamin antioxidants, and cardiovascular mortality: a 9-year follow-up study in the Netherlands

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Serum fatty acids, apolipoproteins, selenium and vitamin antioxidants and the risk of death from coronary artery disease

1 reference

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7 January 2021

gamma-tocopherol traps mutagenic electrophiles such as NO(X) and complements alpha-tocopherol: physiological implications

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

The effect of alpha-tocopherol on the nitration of gamma-tocopherol by peroxynitrite

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Role of oxidatively modified low density lipoproteins and anti-oxidants in atherothrombosis

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

The role of carotid arterial intima-media thickness in predicting clinical coronary events

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900224-5

7 January 2021

Intimal plus medial thickness of the arterial wall: a direct measurement with ultrasound imaging

1 reference

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7 January 2021

Dietary antioxidants and carotid artery wall thickness. The ARIC Study. Atherosclerosis Risk in Communities Study

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7 January 2021

Inverse relation between the concentration of low-density-lipoprotein vitamin E and severity of coronary artery disease

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7 January 2021

The Cholesterol Lowering Atherosclerosis Study (CLAS): design, methods, and baseline results

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7 January 2021

Serial coronary angiographic evidence that antioxidant vitamin intake reduces progression of coronary artery atherosclerosis

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7 January 2021

Effect of supplementary antioxidant vitamin intake on carotid arterial wall intima-media thickness in a controlled clinical trial of cholesterol lowering.

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7 January 2021

Beneficial effects of colestipol-niacin therapy on the common carotid artery. Two- and four-year reduction of intima-media thickness measured by ultrasound

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7 January 2021

Beneficial effects of colestipol-niacin on coronary atherosclerosis. A 4-year follow-up

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7 January 2021

Evaluation of computerized edge tracking for quantifying intima-media thickness of the common carotid artery from B-mode ultrasound images

1 reference

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7 January 2021

Combined effects of lipid peroxidation and antioxidant status on carotid atherosclerosis in a population aged 59-71 y: The EVA Study. Etude sur le Vieillisement Artériel.

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7 January 2021

Probucol and multivitamins in the prevention of restenosis after coronary angioplasty. Multivitamins and Probucol Study Group

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7 January 2021

Antioxidant vitamins in the prevention of cancer

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7 January 2021

Redox cycling and lipid peroxidation: the central role of iron chelates

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7 January 2021

Ascorbate autoxidation in the presence of iron and copper chelates

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7 January 2021

Ascorbate oxidation: UV absorbance of ascorbate and ESR spectroscopy of the ascorbyl radical as assays for iron

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7 January 2021

High-dose vitamin C: a risk for persons with high iron stores?

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7 January 2021

Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis

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7 January 2021

Uric acid: functions and determination

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7 January 2021

Uric acid is a major antioxidant in human nasal airway secretions

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7 January 2021

Beta carotene: from biochemistry to clinical trials.

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7 January 2021

Can antioxidant vitamins materially reduce oxidative damage in humans?

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7 January 2021

Vitamin E administration improves impairment of endothelium-dependent vasodilation in patients with coronary spastic angina

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7 January 2021

Treatment of intermittent claudication with vitamin E

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7 January 2021

Long-time treatment of intermittent claudication with vitamin E.

1 reference

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7 January 2021

Effect of α-Tocopherol (Vitamin E) and β-Carotene Supplementation on the Incidence of Intermittent Claudication in Male Smokers

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7 January 2021

Mortality in the CHAOS trial

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7 January 2021

Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico

1 reference

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7 January 2021

Human plasma and tissue alpha-tocopherol concentrations in response to supplementation with deuterated natural and synthetic vitamin E.

1 reference

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7 January 2021

Nutrition intervention trials in Linxian, China: supplementation with specific vitamin/mineral combinations, cancer incidence, and disease-specific mortality in the general population

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7 January 2021

Alpha-Tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: effects of base-line characteristics and study compliance

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7 January 2021

The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers

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7 January 2021

Prostate Cancer and Supplementation With α-Tocopherol and β-Carotene: Incidence and Mortality in a Controlled Trial

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7 January 2021

Effect of vitamin E and beta carotene on the incidence of primary nonfatal myocardial infarction and fatal coronary heart disease

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7 January 2021

Effects of alpha tocopherol and beta carotene supplements on symptoms, progression, and prognosis of angina pectoris

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7 January 2021

Vitamin E. An inhibitor of the platelet release reaction

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7 January 2021

Plasma antioxidants and cognitive performance in middle-aged and older adults: results of the Austrian Stroke Prevention Study

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7 January 2021

Spontaneous abortion and exposure to electric blankets and heated water beds

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7 January 2021

Cancer statistics, 1999.

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7 January 2021

Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men

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7 January 2021

Aspirin protects endothelial cells from oxidative stress--possible synergism with vitamin E.

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7 January 2021

AHA Science Advisory. Antioxidant consumption and risk of coronary heart disease: emphasison vitamin C, vitamin E, and beta-carotene: A statement for healthcare professionals from the American Heart Association

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7 January 2021

Antioxidants in cardiovascular disease: randomized trials.

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7 January 2021

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7 January 2021

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7 January 2021

1 reference

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7 January 2021

1 reference

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7 January 2021

Tocopherol-mediated peroxidation of lipoproteins: implications for vitamin E as a potential antiatherogenic supplement

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7 January 2021

10.1016/S0891-5849(99)00224-5

Identifiers

DOI

1 reference

release_zgbnbk4gy5dn3peqswwldzjy6i

29 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zgbnbk4gy5dn3peqswwldzjy6i

24 November 2022

mapped directly with Wikidata item

1 reference