(Q33831329)

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Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling

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scholarly article

1 reference

Europe PubMed Central

29 July 2017

Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling (English)

1 reference

Europe PubMed Central

29 July 2017

author name string

Mallika Valapala

1

1 reference

Europe PubMed Central

29 July 2017

Christine Wilson

2

1 reference

Europe PubMed Central

29 July 2017

Stacey Hose

3

1 reference

Europe PubMed Central

29 July 2017

Imran A Bhutto

4

1 reference

Europe PubMed Central

29 July 2017

Rhonda Grebe

5

1 reference

Europe PubMed Central

29 July 2017

Aling Dong

6

1 reference

Europe PubMed Central

29 July 2017

Seth Greenbaum

7

1 reference

Europe PubMed Central

29 July 2017

Limin Gu

8

1 reference

Europe PubMed Central

29 July 2017

Samhita Sengupta

9

1 reference

Europe PubMed Central

29 July 2017

Marisol Cano

10

1 reference

Europe PubMed Central

29 July 2017

Sean Hackett

11

1 reference

Europe PubMed Central

29 July 2017

Guotong Xu

12

1 reference

Europe PubMed Central

29 July 2017

Gerard A Lutty

13

1 reference

Europe PubMed Central

29 July 2017

Lijin Dong

14

1 reference

Europe PubMed Central

29 July 2017

Yuri Sergeev

15

1 reference

Europe PubMed Central

29 July 2017

James T Handa

16

1 reference

Europe PubMed Central

29 July 2017

Peter Campochiaro

17

1 reference

Europe PubMed Central

29 July 2017

Eric Wawrousek

18

1 reference

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29 July 2017

J Samuel Zigler

19

1 reference

Europe PubMed Central

29 July 2017

Debasish Sinha

20

1 reference

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29 July 2017

publication date

23 January 2014

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Europe PubMed Central

29 July 2017

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Europe PubMed Central

29 July 2017

10

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Europe PubMed Central

29 July 2017

3

1 reference

Europe PubMed Central

29 July 2017

480-496

1 reference

Europe PubMed Central

29 July 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4077886/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Autophagy activation clears ELAVL1/HuR-mediated accumulation of SQSTM1/p62 during proteasomal inhibition in human retinal pigment epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Noncanonical autophagy promotes the visual cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Lipid droplets, perilipins and cytokeratins--unravelled liaisons in epithelium-derived cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Impaired endolysosomal function disrupts Notch signalling in optic nerve astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

It's a cell-eat-cell world: autophagy and phagocytosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

VMA21 deficiency prevents vacuolar ATPase assembly and causes autophagic vacuolar myopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Guidelines for the use and interpretation of assays for monitoring autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Reduced cathepsins B and D cause impaired autophagic degradation that can be almost completely restored by overexpression of these two proteases in Sap C-deficient fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Diurnal, localized exposure of phosphatidylserine by rod outer segment tips in wild-type but not Itgb5-/- or Mfge8-/- mouse retina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

βA3/A1-crystallin is required for proper astrocyte template formation and vascular remodeling in the retina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Lysosomal acidification mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Lysosomal function and dysfunction: mechanism and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

A novel melano-lysosome in the retinal epithelium of rhesus monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

βA3/A1-Crystallin controls anoikis-mediated cell death in astrocytes by modulating PI3K/AKT/mTOR and ERK survival pathways through the PKD/Bit1-signaling axis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Endosome maturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Lysosomal positioning coordinates cellular nutrient responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Mutation in the βA3/A1-crystallin gene impairs phagosome degradation in the retinal pigmented epithelium of the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Generation of Cre transgenic mice with postnatal RPE-specific ocular expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

The retinal pigment epithelium in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Termination of autophagy and reformation of lysosomes regulated by mTOR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Regulation and isoform function of the V-ATPases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Altered lipid content inhibits autophagic vesicular fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Methods in mammalian autophagy research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Phagocytosis of retinal rod and cone photoreceptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Regulation of the V-ATPase along the endocytic pathway occurs through reversible subunit association and membrane localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Retinyl ester homeostasis in the adipose differentiation-related protein-deficient retina

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Lysosomal myopathies: an excessive build-up in autophagosomes is too much to handle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Anti-cancer agent siramesine is a lysosomotropic detergent that induces cytoprotective autophagosome accumulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

The autophagy-lysosomal degradation pathway: role in neurodegenerative disease and therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

betaA3/A1-crystallin in astroglial cells regulates retinal vascular remodeling during development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Potential compensatory responses through autophagic/lysosomal pathways in neurodegenerative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Antioxidants reduce cone cell death in a model of retinitis pigmentosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Protein degradation and aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

The retinal pigment epithelium in visual function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Autophagy in health and disease: a double-edged sword

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Beta-crystallin association

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

The role of macroautophagy in the ageing process, anti-ageing intervention and age-associated diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Autophagy, proteasomes, lipofuscin, and oxidative stress in the aging brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Autophagy: molecular mechanisms, physiological functions and relevance in human pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Lysosome and lysosome-related organelles responsible for specialized functions in higher organisms, with special emphasis on vacuolar-type proton ATPase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Abnormal phagocytosis by retinal pigmented epithelium that lacks myosin VIIa, the Usher syndrome 1B protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Autophagic cell death and its execution by lysosomal cathepsins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

When lysosomes get old.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Chemistry and structure activity relationships of bafilomycin A1, a potent and selective inhibitor of the vacuolar H+-ATPase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Modulation of cathepsin D activity in retinal pigment epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Bafilomycins and concanamycins as inhibitors of V-ATPases and P-ATPases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

A novel accessory subunit for vacuolar H(+)-ATPase from chromaffin granules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Enhanced expression of intracellular adhesion molecule-1 and P-selectin in the diabetic human retina and choroid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Inhibition of lysosomal function in red and white skeletal muscles by chloroquine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Antigenic heterogeneity of vascular endothelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

X-linked myopathy with excessive autophagy: a new hereditary muscle disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4077886

28 July 2018

Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27292

21 January 2018

Regulation of TFEB and V-ATPases by mTORC1.

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27292

21 January 2018

Adipophilin is a specific marker of lipid accumulation in diverse cell types and diseases

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27292

21 January 2018

Activation of lysosomal function during dendritic cell maturation

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27292

21 January 2018

Live imaging of neuronal degradation by microglia reveals a role for v0-ATPase a1 in phagosomal fusion in vivo

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27292

21 January 2018

Monitoring autophagic degradation of p62/SQSTM1.

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27292

21 January 2018

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27292

21 January 2018

Amino acids and mTORC1: from lysosomes to disease

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27292

21 January 2018

Ultra-fast FFT protein docking on graphics processors.

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27292

21 January 2018

A competitive hexapeptide inhibitor of annexin A2 prevents hypoxia-induced angiogenic events

1 reference

https://api.crossref.org/works/10.4161%2FAUTO.27292

21 January 2018

Purification and proteomic analysis of lysosomal integral membrane proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monomer-dimer equilibrium of normal and modified beta A3-crystallins: experimental determination and molecular modeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysosomal pool of free-amino acids

1 reference

https://pubmed.ncbi.nlm.nih.gov/24468901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4161/AUTO.27292

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

ResearchGate publication ID

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