(Q33832871)

29 July 2017

Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations (English)

1 reference

29 July 2017

0 references

frontotemporal dementia

1 reference

Christine Van Broeckhoven

inferred from title

author

15

Christine Van Broeckhoven

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Julie van der Zee

12

Julie van der Zee

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Daniel J Metcalf

Daniel Metcalf

4

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Kristina E Parley

Kristina Froud

6

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Peter Johannsen

Peter Johannsen

9

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Clare E Futter

Clare Futter

18

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Elizabeth M. C. Fisher

11

Elizabeth M C Fisher

1 reference

29 July 2017

1

Hazel Urwin

1 reference

29 July 2017

2

Astrid Authier

1 reference

29 July 2017

14

FReJA Consortium

1 reference

29 July 2017

16

John Collinge

1 reference

29 July 2017

19

Adrian M Isaacs

1 reference

29 July 2017

13

Marc Bruyland

1 reference

29 July 2017

Jorgen E Nielsen

3

1 reference

29 July 2017

Caroline Powell

5

1 reference

29 July 2017

Denise S Malcolm

7

1 reference

29 July 2017

Ida Holm

8

1 reference

29 July 2017

Jeremy Brown

10

1 reference

29 July 2017

Sebastian Brandner

17

1 reference

29 July 2017

10 March 2010

1 reference

29 July 2017

Human Molecular Genetics

1 reference

29 July 2017

19

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29 July 2017

11

1 reference

29 July 2017

2228-2238

1 reference

describes a project that uses

29 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2865375/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Genetic screen identifies serpin5 as a regulator of the toll pathway and CHMP2B toxicity associated with frontotemporal dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

GISP increases neurotransmitter receptor stability by down-regulating ESCRT-mediated lysosomal degradation.

28 July 2018

1 reference

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The role of CHMP2B in frontotemporal dementia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Functional reconstitution of ESCRT-III assembly and disassembly

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

GISP binding to TSG101 increases GABA receptor stability by down-regulating ESCRT-mediated lysosomal degradation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Functional characterization of Rab7 mutant proteins associated with Charcot-Marie-Tooth type 2B disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Plasma membrane deformation by circular arrays of ESCRT-III protein filaments

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

CHMP2B C-truncating mutations in frontotemporal lobar degeneration are associated with an aberrant endosomal phenotype in vitro

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

ESCRT-III recognition by VPS4 ATPases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Lysosomes: fusion and function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Polarized signaling endosomes coordinate BDNF-induced chemotaxis of cerebellar precursors.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Structure/function analysis of four core ESCRT-III proteins reveals common regulatory role for extreme C-terminal domain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Release of autoinhibition converts ESCRT-III components into potent inhibitors of HIV-1 budding

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Loss of autophagy in the central nervous system causes neurodegeneration in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Rab conversion as a mechanism of progression from early to late endosomes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Identification of mammalian Vps24p as an effector of phosphatidylinositol 3,5-bisphosphate-dependent endosome compartmentalization

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Receptor downregulation and multivesicular-body sorting

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Retrograde neurotrophin signaling: Trk-ing along the axon

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Nerve growth factor activates persistent Rap1 signaling in endosomes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Vacuolar import of proteins and organelles from the cytoplasm

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Multivesicular endosomes containing internalized EGF-EGF receptor complexes mature and then fuse directly with lysosomes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

In exocrine pancreas, the basolateral endocytic pathway converges with the autophagic pathway immediately after the early endosome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Membrane scission by the ESCRT-III complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Presymptomatic generalized brain atrophy in frontotemporal dementia caused by CHMP2B mutation.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Down-regulation of epidermal growth factor receptor signalling within multivesicular bodies

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Ordered assembly of the ESCRT-III complex on endosomes is required to sequester cargo during MVB formation.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Toll-like receptors in neurodegeneration.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Lack of TAR-DNA binding protein-43 (TDP-43) pathology in human prion diseases.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Frontotemporal dementia linked to chromosome 3 (FTD-3)--current concepts and the detection of a previously unknown branch of the Danish FTD-3 family.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Roles of ESCRT in autophagy-associated neurodegeneration

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Structural basis for selective recognition of ESCRT-III by the AAA ATPase Vps4

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

The localization, trafficking and retrograde transport of BDNF bound to p75NTR in sympathetic neurons

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Mutations in the small GTP-ase late endosomal protein RAB7 cause Charcot-Marie-Tooth type 2B neuropathy

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Chromosome 3 linked frontotemporal dementia (FTD-3).

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

Genetic Variability in CHMP2B and Frontotemporal Dementia

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865375

29 October 2018

Frontotemporal dementia

1 reference

12 December 2020

Prelysosomal convergence of autophagic and endocytic pathways

1 reference

12 December 2020

A Reassessment of the Neuropathology of Frontotemporal Dementia Linked to Chromosome 3

1 reference

12 December 2020

Cortical volumes and atrophy rates in FTD-3 CHMP2B mutation carriers and related non-carriers

1 reference

12 December 2020

Identifiers

DOI

10.1093/HMG/DDQ100

1 reference

29 July 2017

1 reference

29 July 2017

1 reference