(Q33834813)

29 July 2017

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title

Phenotype vs genotype in the evolution of astrocytic brain tumors (English)

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29 July 2017

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P Kleihues

1

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29 July 2017

H Ohgaki

series ordinal

2

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29 July 2017

language of work or name

English

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publication date

1 January 2000

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29 July 2017

published in

Toxicologic Pathology

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29 July 2017

volume

28

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29 July 2017

issue

1

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29 July 2017

page(s)

164-170

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Regulation of mdm2 expression by p53: alternative promoters produce transcripts with nonidentical translation potential

29 July 2017

cites work

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Alterations of cell cycle regulatory genes in primary (de novo) and secondary glioblastomas

21 January 2018

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Patient age, histologic features, and length of survival in patients with glioblastoma multiforme.

21 January 2018

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Molecular genetic correlates of p16, cdk4, and pRb immunohistochemistry in glioblastomas

21 January 2018

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The prognostic impact of prior low grade histology in patients with anaplastic gliomas: a case-control study

21 January 2018

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PTEN mutations in gliomas and glioneuronal tumors.

21 January 2018

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Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails

21 January 2018

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Acquisition of the glioblastoma phenotype during astrocytoma progression is associated with loss of heterozygosity on 10q25-qter

21 January 2018

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Deletion mapping of the long arm of chromosome 10 in glioblastoma multiforme

21 January 2018

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Biochemical properties and biological effects of p53.

21 January 2018

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Association of EGFR gene amplification and CDKN2 (p16/MTS1) gene deletion in glioblastoma multiforme

21 January 2018

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The new WHO classification of brain tumours

21 January 2018

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MDM2 and p53 expression in gliomas: a multivariate survival analysis including proliferation markers and epidermal growth factor receptor

21 January 2018

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Pathways leading to glioblastoma multiforme: a molecular analysis of genetic alterations in 65 astrocytic tumors.

21 January 2018

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PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

21 January 2018

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Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

21 January 2018

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A tiger behind many doors: multiple genetic pathways to malignant glioma

21 January 2018

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DMBT1, a new member of the SRCR superfamily, on chromosome 10q25.3-26.1 is deleted in malignant brain tumours

21 January 2018

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Necrosis as a prognostic criterion in malignant supratentorial, astrocytic gliomas

21 January 2018

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Survival of patients with glioblastoma multiforme is not influenced by altered expression of p16, p53, EGFR, MDM2 or Bcl-2 genes

21 January 2018

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A correlative study of p53 protein alteration and p53 gene mutation in glioblastoma multiforme

21 January 2018

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Mutations in the p53 gene occur in diverse human tumour types

21 January 2018

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A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

21 January 2018

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Genetic alterations associated with the evolution and progression of astrocytic brain tumours

21 January 2018

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Malignant monstrocellular brain tumours. A study of 42 surgically treated cases

21 January 2018

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The p53-mdm2 autoregulatory feedback loop: a paradigm for the regulation of growth control by p53?

21 January 2018

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The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

21 January 2018

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Enhanced tumorigenic behavior of glioblastoma cells expressing a truncated epidermal growth factor receptor is mediated through the Ras-Shc-Grb2 pathway

21 January 2018

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Clonal expansion of p53 mutant cells is associated with brain tumour progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800121

Alternatively spliced mdm2 transcripts with loss of p53 binding domain sequences: transforming ability and frequent detection in human cancer.

21 January 2018

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Molecular analysis of two putative tumour suppressor genes, PTEN and DMBT, which have been implicated in glioblastoma multiforme disease progression.

21 January 2018

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Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

21 January 2018

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Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas

21 January 2018

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PTEN (MMAC1) mutations are frequent in primary glioblastomas (de novo) but not in secondary glioblastomas

21 January 2018

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Necrogenesis and Fas/APO-1 (CD95) expression in primary (de novo) and secondary glioblastomas

21 January 2018

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The multistep nature of cancer

21 January 2018

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Association of epidermal growth factor receptor gene amplification with loss of chromosome 10 in human glioblastoma multiforme

21 January 2018

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https://api.crossref.org/works/10.1177%2F019262330002800121

Subsets of glioblastoma multiforme defined by molecular genetic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800121

Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800121

Structural alterations of the epidermal growth factor receptor gene in human gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800121

A functional p53-responsive intronic promoter is contained within the humanmdm2gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F019262330002800121

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

1 reference

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ONCOGENESIS: Landscaping the Cancer Terrain

21 January 2018

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10.1177/019262330002800121

21 January 2018

Identifiers

DOI

1 reference

29 July 2017

1 reference