(Q40525130)

21 September 2017

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title

Biochemical properties and biological effects of p53. (English)

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21 September 2017

Haffner R

1

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21 September 2017

Oren M

series ordinal

2

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21 September 2017

language of work or name

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1 February 1995

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Current Opinion in Genetics & Development

21 September 2017

published in

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21 September 2017

volume

5

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21 September 2017

issue

1

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21 September 2017

page(s)

84-90

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The tumor suppressor genes

21 September 2017

cites work

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https://api.crossref.org/works/10.1016%2FS0959-437X%2895%2990058-6

7 January 2021

The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots

1 reference

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7 January 2021

A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein

1 reference

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7 January 2021

Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants.

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7 January 2021

p53 domains: identification and characterization of two autonomous DNA-binding regions.

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7 January 2021

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

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7 January 2021

High-resolution structure of the oligomerization domain of p53 by multidimensional NMR

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7 January 2021

How loops, beta sheets, and alpha helices help us to understand p53.

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7 January 2021

Analysis of the most representative tumour-derived p53 mutants reveals that changes in protein conformation are not correlated with loss of transactivation or inhibition of cell proliferation.

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7 January 2021

Transcriptional activation by p53 correlates with suppression of growth but not transformation.

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7 January 2021

WAF1, a potential mediator of p53 tumor suppression

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7 January 2021

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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7 January 2021

p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.

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Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen

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The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

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Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1

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7 January 2021

No room at the p53 inn

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7 January 2021

p53-catalyzed annealing of complementary single-stranded nucleic acids

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7 January 2021

The effects of SV40 large T antigen and p53 on nuclear transport capacity in BALB/c 3T3 cells

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7 January 2021

The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes

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7 January 2021

DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways

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7 January 2021

p53-dependent apoptosis suppresses tumor growth and progression in vivo

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7 January 2021

Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal.

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7 January 2021

Wild-type p53 is required for apoptosis induced by growth factor deprivation in factor-dependent leukaemic cells

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7 January 2021

p53-mediated cell death: relationship to cell cycle control

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7 January 2021

Complementation by wild-type p53 of interleukin-6 effects on M1 cells: induction of cell cycle exit and cooperativity with c-myc suppression

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7 January 2021

Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B.

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7 January 2021

Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins.

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Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development

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7 January 2021

p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.

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7 January 2021

Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53

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7 January 2021

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7 January 2021

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

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7 January 2021

10.1016/S0959-437X(95)90058-6

Identifiers

DOI

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21 September 2017

1 reference