(Q33834814)

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In vivo attenuation of simian immunodeficiency virus by disruption of a tyrosine-dependent sorting signal in the envelope glycoprotein cytoplasmic tail

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 July 2017

In vivo attenuation of simian immunodeficiency virus by disruption of a tyrosine-dependent sorting signal in the envelope glycoprotein cytoplasmic tail (English)

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Europe PubMed Central

PubMed publication ID

29 July 2017

Simian immunodeficiency virus

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Michael Henry Malim

10

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Europe PubMed Central

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29 July 2017

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M Marsh

9

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David C. Montefiori

8

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D C Montefiori

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Europe PubMed Central

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29 July 2017

Jeffrey D Dvorin

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ORCID Public Data File 2021

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P N Fultz

1

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Europe PubMed Central

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29 July 2017

P J Vance

2

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29 July 2017

M J Endres

3

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Europe PubMed Central

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29 July 2017

B Tao

4

1 reference

Europe PubMed Central

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29 July 2017

J D Dvorin

5

1 reference

Europe PubMed Central

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29 July 2017

I C Davis

6

1 reference

Europe PubMed Central

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29 July 2017

J D Lifson

7

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Europe PubMed Central

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29 July 2017

J A Hoxie

11

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29 July 2017

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1 January 2001

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Europe PubMed Central

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29 July 2017

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14

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Journal of Virology

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29 July 2017

75

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29 July 2017

1

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29 July 2017

278-291

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Europe PubMed Central

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29 July 2017

The simian immunodeficiency virus envelope glycoprotein contains multiple signals that regulate its cell surface expression and endocytosis

1 reference

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The intracytoplasmic domain of the Env transmembrane protein is a locus for attenuation of simian immunodeficiency virus SIVmac in rhesus macaques.

1 reference

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Unusual polymorphisms in human immunodeficiency virus type 1 associated with nonprogressive infection

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Genetic evidence for an interaction between human immunodeficiency virus type 1 matrix and alpha-helix 2 of the gp41 cytoplasmic tail

1 reference

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1 reference

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Activation of the PAK-related kinase by human immunodeficiency virus type 1 Nef in primary human peripheral blood lymphocytes and macrophages leads to phosphorylation of a PIX-p95 complex

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The AIDS epidemic--considerations for the 21st century

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Genetics of HIV-1 infection: chemokine receptor CCR5 polymorphism and its consequences.

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The structural era of endocytosis

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Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1. A report from the Sydney Blood Bank Cohort

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Polarized human immunodeficiency virus budding in lymphocytes involves a tyrosine-based signal and favors cell-to-cell viral transmission

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Highly attenuated vaccine strains of simian immunodeficiency virus protect against vaginal challenge: inverse relationship of degree of protection with level of attenuation

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Emerging cytopathic and antigenic simian immunodeficiency virus variants influence AIDS progression.

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Induction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chain

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Live attenuated SIV--a model of a vaccine for AIDS.

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Immunization with a live, attenuated simian immunodeficiency virus vaccine leads to restriction of viral diversity in Rhesus macaques not protected from pathogenic challenge

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HLA and HIV-1: heterozygote advantage and B*35-Cw*04 disadvantage

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Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-I trafficking

1 reference

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Interactions of the cytoplasmic domains of human and simian retroviral transmembrane proteins with components of the clathrin adaptor complexes modulate intracellular and cell surface expression of envelope glycoproteins

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A pathogenic threshold of virus load defined in simian immunodeficiency virus- or simian-human immunodeficiency virus-infected macaques

1 reference

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Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity

1 reference

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Viral genetic evolution in macaques infected with molecularly cloned simian immunodeficiency virus correlates with the extent of persistent viremia

1 reference

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A membrane-proximal tyrosine-based signal mediates internalization of the HIV-1 envelope glycoprotein via interaction with the AP-2 clathrin adaptor

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A role for carbohydrates in immune evasion in AIDS.

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The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes

1 reference

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Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection

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Molecular mechanisms for the regulation of HIV replication, persistence and latency

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Identification of highly attenuated mutants of simian immunodeficiency virus

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Interaction of endocytic signals from the HIV-1 envelope glycoprotein complex with members of the adaptor medium chain family

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Infectivity enhancement by human immunodeficiency virus type 1 Nef is independent of its association with a cellular serine/threonine kinase

1 reference

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Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia

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Induction of vigorous cytotoxic T-lymphocyte responses by live attenuated simian immunodeficiency virus.

1 reference

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Clathrin-coated vesicle formation and protein sorting: an integrated process

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Molecular and biological characterization of a neurovirulent molecular clone of simian immunodeficiency virus

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The membrane-proximal intracytoplasmic tyrosine residue of HIV-1 envelope glycoprotein is critical for basolateral targeting of viral budding in MDCK cells

1 reference

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Rhesus macaques previously infected with simian/human immunodeficiency virus are protected from vaginal challenge with pathogenic SIVmac239.

1 reference

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High frequency of defective nef alleles in a long-term survivor with nonprogressive human immunodeficiency virus type 1 infection.

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Human immunodeficiency virus type 1 envelope protein endocytosis mediated by a highly conserved intrinsic internalization signal in the cytoplasmic domain of gp41 is suppressed in the presence of the Pr55gag precursor protein

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Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein

1 reference

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An internalization signal in the simian immunodeficiency virus transmembrane protein cytoplasmic domain modulates expression of envelope glycoproteins on the cell surface

1 reference

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Domains of the human immunodeficiency virus type 1 matrix and gp41 cytoplasmic tail required for envelope incorporation into virions.

1 reference

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The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages

1 reference

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Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene.

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Molecular and biological characterization of simian immunodeficiency virus macaque strain 32H proviral clones containing nef size variants.

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Human immunodeficiency virus type 1 Nef associates with a cellular serine kinase in T lymphocytes

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The intracytoplasmic domain of gp41 mediates polarized budding of human immunodeficiency virus type 1 in MDCK cells.

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The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes.

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Pathogenicity of live, attenuated SIV after mucosal infection of neonatal macaques

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Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients

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4 July 2018

Significance of premature stop codons in env of simian immunodeficiency virus

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4 July 2018

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4 July 2018

Induction of AIDS in rhesus monkeys by molecularly cloned simian immunodeficiency virus

1 reference

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4 July 2018

Importance of the nef gene for maintenance of high virus loads and for development of AIDS

1 reference

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4 July 2018

Serine phosphorylation-independent downregulation of cell-surface CD4 by nef

1 reference

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4 July 2018

Effects of deletions in the cytoplasmic domain on biological functions of human immunodeficiency virus type 1 envelope glycoproteins

1 reference

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4 July 2018

Natural HIV-1 NEF accelerates virus replication in primary human lymphocytes

1 reference

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4 July 2018

Protective effects of a live attenuated SIV vaccine with a deletion in the nef gene

1 reference

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4 July 2018

Truncation of the human immunodeficiency virus type 1 transmembrane glycoprotein cytoplasmic domain blocks virus infectivity

1 reference

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4 July 2018

Live attenuated, multiply deleted simian immunodeficiency virus causes AIDS in infant and adult macaques

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29 October 2018

Importance of the intracytoplasmic domain of the simian immunodeficiency virus (SIV) envelope glycoprotein for pathogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113922

29 October 2018

Live attenuated simian immunodeficiency virus (SIV)mac in macaques can induce protection against mucosal infection with SIVsm

1 reference

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29 October 2018

Protective immunity induced by live attenuated simian immunodeficiency virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113922

29 October 2018

Progress in the development of an HIV-1 vaccine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113922

29 October 2018

HIV-1 auxiliary proteins: making connections in a dying cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113922

29 October 2018

Plasma SIV RNA viral load determination by real-time quantification of product generation in reverse transcriptase-polymerase chain reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113922

29 October 2018

HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113922

29 October 2018

Changes in plasma HIV-1 RNA and CD4+ lymphocyte counts and the risk of progression to AIDS. Veterans Affairs Cooperative Study Group on AIDS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113922

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=113922

29 October 2018

Characterization of SIV-specific CD4+ T-helper proliferative responses in macaques immunized with live-attenuated SIV

1 reference

https://pubmed.ncbi.nlm.nih.gov/11119598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective immunity of gene-deleted SHIVs having an HIV-1 Env against challenge infection with a gene-intact SHIV

1 reference

https://pubmed.ncbi.nlm.nih.gov/11119598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retrospective analysis of viral load and SIV antibody responses in rhesus macaques infected with pathogenic SIV: predictive value for disease progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/11119598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization

1 reference

https://pubmed.ncbi.nlm.nih.gov/11119598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prospects for live attenuated HIV

1 reference

https://pubmed.ncbi.nlm.nih.gov/11119598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11119598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Candidate vaccines protect macaques against primate immunodeficiency viruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/11119598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathogenicity and comparative evolution in vivo of the transitional quasispecies SIVsmmPBj8

1 reference

https://pubmed.ncbi.nlm.nih.gov/11119598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calmodulin-binding function of LLP segments from the HIV type 1 transmembrane protein is conserved among natural sequence variants

1 reference

https://pubmed.ncbi.nlm.nih.gov/11119598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macaques infected with live attenuated SIVmac are protected against superinfection via the rectal mucosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/11119598

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.75.1.278-291.2001

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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