(Q33835136)

29 July 2017

title

Nucleotide substitution at major histocompatibility complex class II loci: evidence for overdominant selection (English)

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29 July 2017

2

Nei M

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29 July 2017

Hughes AL

1

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29 July 2017

language of work or name

English

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publication date

1 February 1989

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Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

published in

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29 July 2017

volume

86

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29 July 2017

issue

3

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29 July 2017

page(s)

958-962

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Genetic variability maintained by mutation and overdominant selection in finite populations.

29 July 2017

cites work

1 reference

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Mutations and selection in the generation of class II histocompatibility antigen polymorphism

4 July 2018

1 reference

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Both alpha and beta chains of HLA-DC class II histocompatibility antigens display extensive polymorphism in their amino-terminal domains.

4 July 2018

1 reference

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Isotypic and allotypic variation of human class II histocompatibility antigen alpha-chain genes

4 July 2018

1 reference

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The heavy chain of human B-cell alloantigen HLA-DS has a variable N-terminal region and a constant immunoglobulin-like region

4 July 2018

1 reference

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Structure of the murine immune response I-A beta locus: sequence of the I-A beta gene and an adjacent beta-chain second domain exon

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

Isolation and characterization of a cDNA clone for the murine I-E beta polypeptide chain

4 July 2018

1 reference

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Complete primary structures of the E beta chain and gene of the mouse major histocompatibility complex

4 July 2018

1 reference

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Cloning and sequence analysis of the human major histocompatibility complex gene DC-3 beta

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

The nucleotide sequence of the murine I-E beta b immune response gene: evidence for gene conversion events in class II genes of the major histocompatibility complex

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

The H-2 locus of the mouse: observations and speculations concerning its comparative genetics and its polymorphism

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

Evolutionary significance of the HL-A system

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

Genetics and expression of mouse Ia antigens

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

"Exon-shuffling" maps control of antibody- and T-cell-recognition sites to the NH2-terminal domain of the class II major histocompatibility polypeptide A beta.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

Complete sequence of the HLA DQ alpha and DQ beta cDNA from a DR5/DQw3 cell line

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

Evolution of the major histocompatibility complex.

4 July 2018

1 reference

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DQw1 beta gene from HLA-DR2-Dw12 consists of six exons and expresses multiple DQw1 beta polypeptides through alternative splicing

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

Allelic variation in the DR subregion of the human major histocompatibility complex

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

Evolutionary and genetic implications of sequence variation in two nonallelic HLA-DR beta-chain cDNA sequences

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

Simple methods for estimating the numbers of synonymous and nonsynonymous nucleotide substitutions

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

HLA-A and B polymorphisms predate the divergence of humans and chimpanzees

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selection

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

MHC class II sequences of an HLA-DR2 narcoleptic

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

A hypothetical model of the foreign antigen binding site of class II histocompatibility molecules

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

The beta 1 domain of the mouse E beta chain is important for restricted antigen presentation to helper T-cell hybridomas

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

Sequence and evolution of HLA-DR7- and -DRw53-associated beta-chain genes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

Sequence analysis and structure-function correlations of murine q, k, u, s, and f haplotype I-A beta cDNA clones

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

The human HLA class II alpha chain gene DZ alpha is distinct from genes in the DP, DQ and DR subregions

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

DO beta: a new beta chain gene in HLA-D with a distinct regulation of expression

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

Sequence of gene and cDNA encoding murine major histocompatibility complex class II gene A beta 2.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

Methods for computing the standard errors of branching points in an evolutionary tree and their application to molecular data from humans and apes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

The origin of MHC class II gene polymorphism within the genus Mus.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

Molecular variation of human major histocompatibility complex DQw3 beta-chains

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

Allelic forms of the alpha- and beta-chain genes encoding DQw1-positive heterodimers

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

HLA-DR2 subtypes form an additional supertypic family of DR beta alleles

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

Molecular organization of the class II genes of the human and mouse major histocompatibility complexes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

I-Ad-binding peptides derived from unrelated protein antigens share a common structural motif

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

A molecular basis for the Ia.2 and Ia.19 antigenic determinants

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

A newly characterized HLA-DP beta-chain allele. Evidence for DP beta heterogeneity within the DPw4 specificity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

The relation between major histocompatibility complex (MHC) restriction and the capacity of Ia to bind immunogenic peptides

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

Enhanced immunological surveillance in mice heterozygous at the H-2 gene complex

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

Sequence of an HLA-DR alpha-chain cDNA clone and intron-exon organization of the corresponding gene

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

Nucleotide sequence of a light chain gene of the mouse I-A subregion: A beta d.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

The murine E alpha immune response gene

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

Regions of allelic hypervariability in the murine Aα immune response gene

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

MHC polymorphism pre-dating speciation

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286598

Inherited histocompatibility changes in progeny of irradiated and unirradiated inbred mice

29 October 2018

1 reference

12 December 2020

High codon-usage changes in mammalian genes

1 reference

12 December 2020

The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

1 reference

12 December 2020

Gene clusters and the evolution of the major histocompatibility system

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.86.3.958

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29 July 2017

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29 July 2017

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