(Q33837443)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10674190%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

review article

1 reference

title

Cytochrome P450-mediated drug interactions (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10674190%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

author name string

Flockhart DA

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10674190%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

Oesterheld JR

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10674190%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

publication date

1 January 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10674190%20AND%20SRC:MED&resulttype=core&format=json

Child and Adolescent Psychiatric Clinics of North America

4 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10674190%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10674190%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10674190%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

page(s)

43-76

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10674190%20AND%20SRC:MED&resulttype=core&format=json

Desipramine pharmacokinetics when coadministered with paroxetine or sertraline in extensive metabolizers

4 November 2019

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Macrolides versus azalides: a drug interaction update

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7 January 2021

A mechanistic approach to antiepileptic drug interactions

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7 January 2021

Effect of omeprazole and cimetidine on plasma diazepam levels.

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7 January 2021

Effect of omeprazole treatment on diazepam plasma levels in slow versus normal rapid metabolizers of omeprazole.

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7 January 2021

Diazepam metabolism by human liver microsomes is mediated by both S-mephenytoin hydroxylase and CYP3A isoforms

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7 January 2021

Rifampin drastically reduces plasma concentrations and effects of oral midazolam.

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7 January 2021

Coadministration of nefazodone and benzodiazepines: II. A pharmacokinetic interaction study with triazolam

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7 January 2021

Clinical pharmacokinetics of antiepileptic drugs in paediatric patients. Part II. Phenytoin, carbamazepine, sulthiame, lamotrigine, vigabatrin, oxcarbazepine and felbamate

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7 January 2021

The effect of ciprofloxacin on theophylline pharmacokinetics in healthy subjects.

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7 January 2021

Importance of genetic factors in the regulation of diazepam metabolism: relationship to S-mephenytoin, but not debrisoquin, hydroxylation phenotype.

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7 January 2021

Carbamazepine treatment induces the CYP3A4 catalysed sulphoxidation of omeprazole, but has no or less effect on hydroxylation via CYP2C19.

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7 January 2021

Allelic and functional variability of cytochrome P4502C9.

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7 January 2021

Pharmacokinetics and pharmacodynamics of the enantiomers of warfarin in man

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7 January 2021

Clinical significance of the sparteine/debrisoquine oxidation polymorphism

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7 January 2021

Genetic and environmental factors associated with variation of human xenobiotic glucuronidation and sulfation

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7 January 2021

Fluconazole-induced symptomatic phenytoin toxicity

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7 January 2021

Effects of caffeine withdrawal from the diet on the metabolism of clozapine in schizophrenic patients

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7 January 2021

Interphenotype differences in disposition and effect on gastrin levels of omeprazole--suitability of omeprazole as a probe for CYP2C19

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7 January 2021

Oxidation of acetaminophen to its toxic quinone imine and nontoxic catechol metabolites by baculovirus-expressed and purified human cytochromes P450 2E1 and 2A6

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7 January 2021

Metabolism of Meloxicam in human liver involves cytochromes P4502C9 and 3A4

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7 January 2021

Valproic acid pharmacokinetics in children. IV. Effects of age and antiepileptic drugs on protein binding and intrinsic clearance

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7 January 2021

Onset of xenobiotic metabolism in children: toxicological implications

1 reference

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7 January 2021

Quick onset of severe abdominal pain after codeine in an ultrarapid metabolizer of debrisoquine

1 reference

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7 January 2021

Effect of clarithromycin on the pharmacokinetics and pharmacodynamics of pimozide in healthy poor and extensive metabolizers of cytochrome P450 2D6 (CYP2D6).

1 reference

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7 January 2021

CYP2E1 activity in patients with alcoholic liver disease.

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7 January 2021

Cytochrome P4502E1 inducibility and hydroxyethyl radical formation among alcoholics

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7 January 2021

Same incidence of adverse drug events after codeine administration irrespective of the genetically determined differences in morphine formation

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7 January 2021

Involvement of CYP3A4 and CYP2D6 in the metabolism of haloperidol

1 reference

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7 January 2021

Metabolism of risperidone to 9-hydroxyrisperidone by human cytochromes P450 2D6 and 3A4

1 reference

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7 January 2021

The induction effect of rifampicin on activity of mephenytoin 4'-hydroxylase related to M1 mutation of CYP2C19 and gene dose

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Re: Bradycardia and somnolence after adding fluoxetine to pimozide regimen

1 reference

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7 January 2021

Effect of carbamazepine on the single oral dose pharmacokinetics of alprazolam

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Dose and plasma levels of nortriptyline and chlorpromazine in delusionally depressed adolescents and of nortriptyline in nondelusionally depressed adolescents

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7 January 2021

Therapeutic drug monitoring databases for postmarketing surveillance of drug-drug interactions: evaluation of a paired approach for psychotropic medication.

1 reference

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7 January 2021

Effect of multiple doses of rifampin on the [14C N-methyl] erythromycin breath test in healthy male volunteers.

1 reference

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7 January 2021

Pharmacokinetic drug interactions with antimicrobial agents

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7 January 2021

Pharmacokinetic interactions with felbamate. In vitro-in vivo correlation

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7 January 2021

Elevation of plasma concentrations of haloperidol after the addition of fluoxetine

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7 January 2021

Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily.

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7 January 2021

Clinical importance of the interaction of diazepam and cimetidine.

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7 January 2021

Regioselective and stereoselective metabolism of ibuprofen by human cytochrome P450 2C.

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7 January 2021

Gender effects in pharmacokinetics and pharmacodynamics

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7 January 2021

The effect of codeine on gastrointestinal transit in extensive and poor metabolisers of debrisoquine

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7 January 2021

Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification

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7 January 2021

Human liver microsomal metabolism of the enantiomers of warfarin and acenocoumarol: P450 isozyme diversity determines the differences in their pharmacokinetics

1 reference

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7 January 2021

Unconsciousness associated with midazolam and erythromycin

1 reference

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7 January 2021

Relationship between CYP2C9 and 2C19 genotypes and tolbutamide methyl hydroxylation and S-mephenytoin 4'-hydroxylation activities in livers of Japanese and Caucasian populations

1 reference

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7 January 2021

The effect of caffeine on the pharmacokinetics of acetaminophen in man

1 reference

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7 January 2021

Dose-dependent inhibition of CYP1A2, CYP2C19 and CYP2D6 by citalopram, fluoxetine, fluvoxamine and paroxetine

1 reference

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7 January 2021

The use of therapeutic drug monitoring data to document kinetic drug interactions: an example with amitriptyline and nortriptyline.

1 reference

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7 January 2021

Effects of dietary broccoli on human drug metabolising activity.

1 reference

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7 January 2021

Effect of fluvoxamine therapy on the activities of CYP1A2, CYP2D6, and CYP3A as determined by phenotyping.

1 reference

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7 January 2021

The emerging role of cytochrome P450 3A in psychopharmacology

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7 January 2021

Carbamazepine-induced reduction of blood levels of haloperidol in chronic schizophrenia

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7 January 2021

Effect of rifampin on the plasma concentration and the clinical effect of haloperidol concomitantly administered to schizophrenic patients

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Plasma buspirone concentrations are greatly increased by erythromycin and itraconazole

1 reference

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7 January 2021

An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway

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7 January 2021

Clinical and toxicological consequences of the inductive potential of ethanol

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7 January 2021

The effects of selective serotonin reuptake inhibitors and their metabolites on S-mephenytoin 4'-hydroxylase activity in human liver microsomes

1 reference

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7 January 2021

"It's the genes, stupid". Molecular bases and clinical consequences of genetic cytochrome P450 2D6 polymorphism

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7 January 2021

Mephenytoin hydroxylation deficiency: kinetics after repeated doses

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7 January 2021

The effect of fluvoxamine on the pharmacokinetics and pharmacodynamics of buspirone

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7 January 2021

Cytochrome P450TB (CYP2C): a major monooxygenase catalyzing diclofenac 4'-hydroxylation in human liver

1 reference

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7 January 2021

Substituting carbamazepine with oxcarbazepine increases citalopram levels. A report on two cases

1 reference

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7 January 2021

Cytochrome P450 isozymes and antiepileptic drug interactions

1 reference

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7 January 2021

Cytochrome P-4502E1: its physiological and pathological role

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7 January 2021

Interaction between antidepressants and perphenazine in psychiatric inpatients

1 reference

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7 January 2021

The effects of genetic polymorphisms of CYP2C9 and CYP2C19 on phenytoin metabolism in Japanese adult patients with epilepsy: studies in stereoselective hydroxylation and population pharmacokinetics

1 reference

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7 January 2021

Frequent occurrence of CYP2D6 gene duplication in Saudi Arabians

1 reference

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7 January 2021

Cytochromes P450, 1A2, and 2C9 are responsible for the human hepatic O-demethylation of R- and S-naproxen

1 reference

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7 January 2021

Pharmacokinetic interactions related to the chemical structures of fluoroquinolones

1 reference

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7 January 2021

The effects of perphenazine on the concentration of nortriptyline and its hydroxymetabolites in older patients

1 reference

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7 January 2021

The effect of smoking on caffeine elimination: implications for its use as a semiquantitative test of liver function

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7 January 2021

Pharmacokinetic drug interactions with phenytoin (Part I).

1 reference

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7 January 2021

Newer antidepressants and the cytochrome P450 system

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7 January 2021

Cimetidine interaction with phenytoin.

1 reference

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7 January 2021

A review of developmental aspects of cytochrome P450.

1 reference

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7 January 2021

A potentially hazardous interaction between erythromycin and midazolam.

1 reference

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7 January 2021

Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole.

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7 January 2021

Interaction between grapefruit juice and diazepam in humans.

1 reference

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7 January 2021

Characterization of the cytochrome P450 isoenzymes involved in the in vitro N-dealkylation of haloperidol

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

A comparative review of the pharmacological and toxicological properties of disulfiram and calcium carbimide.

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Pharmacokinetic profile of topiramate in comparison with other new antiepileptic drugs

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Oral phenytoin pharmacokinetics during omeprazole therapy

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Selective serotonin reuptake inhibitors and theophylline metabolism in human liver microsomes: potent inhibition by fluvoxamine

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Lower prevalence of the debrisoquin oxidative poor metabolizer phenotype in American black versus white subjects

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7 January 2021

Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions

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7 January 2021

Pharmacokinetic interactions between antiepileptic drugs. Clinical considerations

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7 January 2021

Enzyme activities of the hindgut microflora of laboratory animals and man

1 reference

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7 January 2021

Changing patterns of psychotropic medications prescribed by child psychiatrists in the 1990s.

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7 January 2021

Pharmacokinetics of pimozide in adults and children with Tourette's syndrome

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7 January 2021

Influence of usual intake of dietary caffeine on single-dose kinetics of theophylline in healthy human subjects

1 reference

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7 January 2021

Characterization of six in vitro reactions mediated by human cytochrome P450: application to the testing of cytochrome P450-directed antibodies

1 reference

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7 January 2021

Inhibition of CYP2C9 by selective serotonin reuptake inhibitors in vitro: studies of phenytoin p-hydroxylation

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Plasma Protein Displacement Interactions Are Rarely of Clinical Significance

1 reference

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7 January 2021

Identification of the human and animal hepatic cytochromes P450 involved in clonazepam metabolism

1 reference

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7 January 2021

Metabolic disposition of lansoprazole in relation to the S-mephenytoin 4'-hydroxylation phenotype status

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Effect of cigarette smoking on fluvoxamine pharmacokinetics in humans

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Selective serotonin reuptake inhibitors and CNS drug interactions. A critical review of the evidence

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Phenytoin age-dose-concentration relationship in children

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Metabolism of warfarin enantiomers in Japanese patients with heart disease having different CYP2C9 and CYP2C19 genotypes.

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Developmental changes in urinary elimination of theophylline and its metabolites in pediatric patients

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Expression of CYP2D6 in developing human liver

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Genetically deficient CYP2D6 metabolism provides protection against oral opiate dependence.

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Neuroleptic Plasma Levels

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Fluvoxamine and fluoxetine: interaction studies with amitriptyline, clomipramine and neuroleptics in phenotyped patients

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Interactions between cyclosporine and newer antidepressant medications

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Inhibition of alprazolam and desipramine hydroxylation in vitro by paroxetine and fluvoxamine: comparison with other selective serotonin reuptake inhibitor antidepressants

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Phenacetin O-deethylation by human liver microsomes in vitro: inhibition by chemical probes, SSRI antidepressants, nefazodone and venlafaxine

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Midazolam hydroxylation by human liver microsomes in vitro: inhibition by fluoxetine, norfluoxetine, and by azole antifungal agents.

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Induction of CYP2D6 in pregnancy

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Drug interactions of macrolides: emphasis on dirithromycin

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Interactions of warfarin with drugs and food

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Pharmacokinetic interactions of clozapine with selective serotonin reuptake inhibitors: differential effects of fluvoxamine and paroxetine in a prospective study

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Ventricular tachycardia associated with desipramine and thioridazine

1 reference

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7 January 2021

Isolation and characterization of human liver cytochrome P450 2C19: correlation between 2C19 and S-mephenytoin 4'-hydroxylation

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

A kinetic and dynamic study of oral alprazolam with and without erythromycin in humans: in vivo evidence for the involvement of CYP3A4 in alprazolam metabolism.

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Acute accidental overdosage of haloperidol in children

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Haloperidol and torsades de pointes

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Induction of polymorphic 4'-hydroxylation of S-mephenytoin by rifampicin

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

Acetaminophen (paracetamol) hepatotoxicity with regular intake of alcohol: analysis of instances of therapeutic misadventure

1 reference

https://api.crossref.org/works/10.1016%2FS1056-4993%2818%2930135-4

7 January 2021

10.1016/S1056-4993(18)30135-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10674190%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

1 reference