(Q33839529)

29 July 2017

title

Guggulsterone targets smokeless tobacco induced PI3K/Akt pathway in head and neck cancer cells (English)

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29 July 2017

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head and neck carcinoma

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Muzafar A Macha

1

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29 July 2017

Ajay Matta

2

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29 July 2017

Shyam Singh Chauhan

3

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29 July 2017

K W Michael Siu

4

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29 July 2017

Ranju Ralhan

5

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29 July 2017

language of work or name

English

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publication date

24 February 2011

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29 July 2017

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29 July 2017

volume

6

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29 July 2017

issue

2

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29 July 2017

page(s)

e14728

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Creative Commons Attribution 4.0 International

29 July 2017

copyright license

start time

24 February 2011

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Guggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3

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Guggulsterone induces apoptosis in colon cancer cells and inhibits tumor growth in murine colorectal cancer xenografts

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Oncogenic mutations of the PIK3CA gene in head and neck squamous cell carcinomas

5 July 2018

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Guggulsterone-induced apoptosis in human prostate cancer cells is caused by reactive oxygen intermediate dependent activation of c-Jun NH2-terminal kinase

5 July 2018

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Guggulsterone inhibits tumor cell proliferation, induces S-phase arrest, and promotes apoptosis through activation of c-Jun N-terminal kinase, suppression of Akt pathway, and downregulation of antiapoptotic gene products.

5 July 2018

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Expression of the bile acid receptor FXR in Barrett's esophagus and enhancement of apoptosis by guggulsterone in vitro.

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Guggulsterones induce apoptosis and differentiation in acute myeloid leukemia: identification of isomer-specific antileukemic activities of the pregnadienedione structure

5 July 2018

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Expression of Stat5A in tobacco chewing-mediated oral squamous cell carcinoma

5 July 2018

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Caspase-dependent apoptosis induction by guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, in PC-3 human prostate cancer cells is mediated by Bax and Bak.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Guggulsterone inhibits NF-kappaB and IkappaBalpha kinase activation, suppresses expression of anti-apoptotic gene products, and enhances apoptosis

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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State of p53, Rb and DCC tumor suppressor genes in human oral cancer cell lines

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044714

Most human squamous cell carcinomas in the oral cavity contain mutated p53 tumor-suppressor genes

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044714

Analysis of 23 polycyclic aromatic hydrocarbons in smokeless tobacco by gas chromatography-mass spectrometry

5 July 2018

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A natural product that lowers cholesterol as an antagonist ligand for FXR.

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21 January 2018

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Smokeless tobacco (khaini) extracts modulate gene expression in epithelial cell culture from an oral hyperplasia.

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Adult tobacco survey - 19 States, 2003-2007.

21 January 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3044714

Curcumin down regulates smokeless tobacco-induced NF-kappaB activation and COX-2 expression in human oral premalignant and cancer cells

29 October 2018

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12 December 2020

Smokeless tobacco and tobacco-related nitrosamines

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12 December 2020

Cytoplasmic accumulation of activated leukocyte cell adhesion molecule is a predictor of disease progression and reduced survival in oral cancer patients

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12 December 2020

Phenotypic alterations in Rb pathway have more prognostic influence than p53 pathway proteins in oral carcinoma

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12 December 2020

Alterations of rb pathway components are frequent events in patients with oral epithelial dysplasia and predict clinical outcome in patients with squamous cell carcinoma

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12 December 2020

10.1371/JOURNAL.PONE.0014728

Identifiers

DOI

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29 July 2017

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29 July 2017

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