(Q40523660)

English

Guggulsterone inhibits NF-kappaB and IkappaBalpha kinase activation, suppresses expression of anti-apoptotic gene products, and enhances apoptosis

scientific article published on 17 August 2004

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scholarly article

1 reference

Europe PubMed Central

21 September 2017

Guggulsterone inhibits NF-kappaB and IkappaBalpha kinase activation, suppresses expression of anti-apoptotic gene products, and enhances apoptosis (English)

1 reference

Europe PubMed Central

21 September 2017

apoptotic process

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(E)-guggulsterone

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Shishir Shishodia

1

1 reference

Europe PubMed Central

21 September 2017

Bharat B Aggarwal

2

1 reference

Europe PubMed Central

21 September 2017

language of work or name

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publication date

17 August 2004

1 reference

Europe PubMed Central

21 September 2017

number of pages

11

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

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Europe PubMed Central

21 September 2017

279

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Europe PubMed Central

21 September 2017

47148-47158

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Europe PubMed Central

21 September 2017

45

1 reference

Europe PubMed Central

21 September 2017

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1 reference

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Inflammation and cancer: back to Virchow?

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GUGULIPID: a natural cholesterol-lowering agent

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Guggulsterone: an old approach to a new problem

1 reference

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A natural product that lowers cholesterol as an antagonist ligand for FXR.

1 reference

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The hypolipidemic natural product guggulsterone acts as an antagonist of the bile acid receptor

1 reference

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Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump

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Methotrexate suppresses NF-kappaB activation through inhibition of IkappaBalpha phosphorylation and degradation

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1 reference

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1 reference

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Studies into the effect of the tyrosine kinase inhibitor herbimycin A on NF-kappa B activation in T lymphocytes. Evidence for covalent modification of the p50 subunit

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Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B

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Tumor necrosis factor alpha-induced phosphorylation of I kappa B alpha is a signal for its degradation but not dissociation from NF-kappa B

1 reference

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Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

1 reference

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TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

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Mechanisms by which IkappaB proteins control NF-kappaB activity

1 reference

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21 January 2018

Transcriptional roles of nuclear factor kappa B and nuclear factor-interleukin-6 in the tumor necrosis factor alpha-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells

1 reference

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Protein kinase C-zeta regulates transcription of the matrix metalloproteinase-9 gene induced by IL-1 and TNF-alpha in glioma cells via NF-kappa B

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NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1.

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Activation of c-myc promoter P1 by immunoglobulin kappa gene enhancers in Burkitt lymphoma: functional characterization of the intron enhancer motifs kappaB, E box 1 and E box 2, and of the 3' enhancer motif PU.

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Anti-apoptotic protein survivin plays a significant role in tubular morphogenesis of human coronary arteriolar endothelial cells by hypoxic preconditioning

1 reference

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Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

1 reference

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ch-IAP1, a member of the inhibitor-of-apoptosis protein family, is a mediator of the antiapoptotic activity of the v-Rel oncoprotein

1 reference

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Transcriptional regulation of bcl-2 by nuclear factor kappa B and its significance in prostate cancer

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Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis

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The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis

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NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling

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Suppression of TNF-alpha-induced apoptosis by NF-kappaB

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Identifiers

10.1074/JBC.M408093200

1 reference

Europe PubMed Central

21 September 2017

1 reference

Europe PubMed Central

21 September 2017

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