(Q33843902)

English

Interleukin-12 (IL-12) and IL-18 are important in innate defense against genital herpes simplex virus type 2 infection in mice but are not required for the development of acquired gamma interferon-mediated protective immunity

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scholarly article

1 reference

Europe PubMed Central

29 July 2017

Interleukin-12 (IL-12) and IL-18 are important in innate defense against genital herpes simplex virus type 2 infection in mice but are not required for the development of acquired gamma interferon-mediated protective immunity (English)

1 reference

Europe PubMed Central

29 July 2017

sexual transmission

0 references

0 references

1 reference

based on heuristic

inferred from title

3

object named as

Holmgren J

1 reference

Europe PubMed Central

29 July 2017

author name string

Harandi AM

1

1 reference

Europe PubMed Central

29 July 2017

Svennerholm B

2

1 reference

Europe PubMed Central

29 July 2017

Eriksson K

4

1 reference

Europe PubMed Central

29 July 2017

publication date

1 July 2001

1 reference

Europe PubMed Central

29 July 2017

Journal of Virology

1 reference

Europe PubMed Central

29 July 2017

75

1 reference

Europe PubMed Central

29 July 2017

6705-6709

1 reference

Europe PubMed Central

29 July 2017

14

1 reference

Europe PubMed Central

29 July 2017

Interleukin-18 (IL-18) enhances innate IL-12-mediated resistance to Toxoplasma gondii

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

Potentiality of interleukin-18 as a useful reagent for treatment and prevention of Leishmania major infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

A novel transcription factor, T-bet, directs Th1 lineage commitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

IL-12 synergizes with IL-18 or IL-1beta for IFN-gamma production from human T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

Regulation of the IL-12/IL-12R axis: a critical step in T-helper cell differentiation and effector function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

Humoral response to herpes simplex virus is complement-dependent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

Neutrophils aid in protection of the vaginal mucosae of immune mice against challenge with herpes simplex virus type 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

Interleukin 18 contributes to host resistance and gamma interferon production in mice infected with virulent Salmonella typhimurium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

Interleukin-18/interferon-gamma-inducing factor, a novel cytokine, up-regulates ICAM-1 (CD54) expression in KG-1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

Interleukin-12 is essential for a protective Th1 response in mice infected with Cryptococcus neoformans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

Mice lacking IL-12 develop polarized Th1 cells during viral infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

IL-12 and IL-18 differentially regulate the transcriptional activity of the human IFN-gamma promoter in primary CD4+ T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

Defective NK cell activity and Th1 response in IL-18-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

Cytokines induce the development of functionally heterogeneous T helper cell subsets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

Clearance of HSV-2 from recurrent genital lesions correlates with infiltration of HSV-specific cytotoxic T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

Mucosal immunity to herpes simplex virus type 2 infection in the mouse vagina is impaired by in vivo depletion of T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

Immunoglobulin G is the main protective antibody in mouse vaginal secretions after vaginal immunization with attenuated herpes simplex virus type 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

Interferon-gamma enhances resolution of herpes simplex virus type 2 infection of the murine genital tract

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

IFN-gamma-inducing factor (IGIF) is a costimulatory factor on the activation of Th1 but not Th2 cells and exerts its effect independently of IL-12.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

Endogenous production of interleukin 15 by activated human monocytes is critical for optimal production of interferon-gamma by natural killer cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

Effect of interleukin 12 neutralization on host resistance and gamma interferon production in mouse typhoid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

Multiple defects of immune cell function in mice with disrupted interferon-gamma genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

Evaluation of solubilized herpes simplex virus membrane antigen by enzyme-linked immunosorbent assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

Immunity in the female genital tract after intravaginal vaccination of mice with an attenuated strain of herpes simplex virus type 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

Antigenic differences between isolates of herpesvirus type 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

5 July 2018

Differential roles of B cells and IFN-gamma-secreting CD4(+) T cells in innate and adaptive immune control of genital herpes simplex virus type 2 infection in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

29 October 2018

In the absence of T cells, natural killer cells protect from mortality due to HSV-1 encephalitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

29 October 2018

The role of gamma interferon in immune resistance to vaginal infection by herpes simplex virus type 2 in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

29 October 2018

T lymphocytes are required for protection of the vaginal mucosae and sensory ganglia of immune mice against reinfection with herpes simplex virus type 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

29 October 2018

Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

29 October 2018

A mouse model for studies of mucosal immunity to vaginal infection by herpes simplex virus type 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

29 October 2018

Parasite-induced IL-12 stimulates early IFN-gamma synthesis and resistance during acute infection with Toxoplasma gondii.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=114395

29 October 2018

Nitric oxide and macrophage antiviral extrinsic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/11413339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12-independent Th1-type immune responses to respiratory viral infection: requirement of IL-18 for IFN-gamma release in the lung but not for the differentiation of viral-reactive Th1-type lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11413339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced host resistance and Th1 response to Cryptococcus neoformans in interleukin-18 deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11413339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A critical role for IL-18 in the proliferation and activation of NK1.1+ CD3- cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11413339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-15 promotes IL-12 production by human monocytes via T cell-dependent contact and may contribute to IL-12-mediated IFN-gamma secretion by CD4+ T cells in the absence of TCR ligation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11413339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12 is not required for induction of type 1 cytokine responses in viral infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/11413339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-10 enhances NK cell proliferation, cytotoxicity and production of IFN-gamma when combined with IL-18

1 reference

https://pubmed.ncbi.nlm.nih.gov/11413339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12-deficient mice are defective in IFN gamma production and type 1 cytokine responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/11413339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NK cell-deficient mice develop a Th1-like response but fail to mount an efficient antigen-specific IgG2a antibody response

1 reference

https://pubmed.ncbi.nlm.nih.gov/11413339

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.75.14.6705-6709.2001

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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