(Q33844142)

29 July 2017

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title

Iron toxicity and chelation therapy (English)

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29 July 2017

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Robert S Britton

1

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29 July 2017

Katherine L Leicester

series ordinal

2

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29 July 2017

Bruce R Bacon

series ordinal

3

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29 July 2017

1 October 2002

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29 July 2017

10

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International Journal of Hematology

inferred from page(s)

published in

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29 July 2017

76

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29 July 2017

3

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29 July 2017

219-228

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https://scigraph.springernature.com/pub.10.1007/bf02982791

29 July 2017

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cites work

The effect of iron overload on rat plasma and liver oxidant status in vivo

1 reference

https://api.crossref.org/works/10.1007%2FBF02982791

The role of iron in ferritin- and haemosiderin-mediated lipid peroxidation in liposomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02982791

Formation of hydroxyl radicals in the presence of ferritin and haemosiderin. Is haemosiderin formation a biological protective mechanism?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02982791

Iron-induced DNA damage and synthesis in isolated rat liver nuclei

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02982791

Biochemical changes in the tissues of animals injected with iron. 3. Lipid peroxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02982791

21 January 2018

Secondary iron overload

1 reference

12 December 2020

A 31P-NMR study on the energy state of rat liver in an experimental model of chronic dietary iron overload

1 reference

12 December 2020

In vivo formation of single-strand breaks in DNA by hydrogen peroxide is mediated by the Haber-Weiss reaction

1 reference

12 December 2020

Formation of 8-hydroxydeoxyguanosine (8-OH-dG) in rat kidney DNA after intraperitoneal administration of ferric nitrilotriacetate (Fe-NTA).

1 reference

12 December 2020

Enhancement by dietary iron of lipid peroxidation in mouse colon.

1 reference

12 December 2020

Studies on the concentration and intracellular localization of iron proteins in liver biopsy specimens from patients with iron overload with special reference to their role in lysosomal disruption.

1 reference

12 December 2020

Meta-analytic review of the clinical effectiveness of oral deferiprone (L1).

1 reference

12 December 2020

Chelation therapy in beta-thalassemia: an optimistic update

1 reference

12 December 2020

Secondary iron overload disorders.

1 reference

12 December 2020

Direct evidence for in vivo hydroxyl-radical generation in experimental iron overload: an ESR spin-trapping investigation

1 reference

12 December 2020

Survival and causes of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis

1 reference

12 December 2020

Cardioprotective effect of alpha-tocopherol, ascorbate, deferoxamine, and deferiprone: mitochondrial function in cultured, iron-loaded heart cells

1 reference

12 December 2020

Chronic dietary iron overload in rats results in impaired calcium sequestration by hepatic mitochondria and microsomes 1, 2, and 3

1 reference

12 December 2020

Excess iron induces hepatic oxidative stress and transforming growth factor beta1 in genetic hemochromatosis.

1 reference

12 December 2020

Toxicity associated with iron overload found in hemochromatosis: possible mechanism in a rat model

1 reference

12 December 2020

Organelle pathology in primary and secondary haemochromatosis with special reference to lysosomal changes

1 reference

12 December 2020

Liver cell damage and lysosomal iron storage in patients with idiopathic hemochromatosis. A light and electron microscopic study

1 reference

12 December 2020

Chronic iron overload causes activation of rat lipocytes in vivo

1 reference

12 December 2020

Deferiprone or fatal iron toxic effects?

1 reference

12 December 2020

Mitochondrial respiratory enzymes are a major target of iron toxicity in rat heart cells

1 reference

12 December 2020

Enhanced γ-Glutamyl Transpeptidase Expression and Selective Loss of CuZn Superoxide Dismutase in Hepatic Iron Overload

1 reference

12 December 2020

Transfusional iron overload and chelation therapy with deferoxamine and deferiprone (L1).

1 reference

12 December 2020

Metals, oxidative stress, and hepatic fibrogenesis

1 reference

12 December 2020

Hepatic mitochondrial energy production in rats with chronic iron overload

1 reference

12 December 2020

Characterization of hepatic iron overload following dietary administration of dicyclopentadienyl iron (Ferrocene) to mice: cellular, biochemical, and molecular aspects

1 reference

12 December 2020

The controversial role of deferiprone in the treatment of thalassemia.

1 reference

12 December 2020

Iron-induced liver injury

1 reference

12 December 2020

Malondialdehyde and 4-hydroxynonenal protein adducts in plasma and liver of rats with iron overload

1 reference

12 December 2020

Mechanistic studies of ionizing radiation and oxidative mutagenesis: genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome.

1 reference

12 December 2020

Ability of the orally effective iron chelators dimethyl- and diethyl-hydroxypyrid-4-one and of deferoxamine to restore sarcolemmal thiolic enzyme activity in iron-loaded heart cells.

1 reference

12 December 2020

Vitamins E and C, beta-carotene, and other carotenoids as antioxidants

1 reference

12 December 2020

Hepatic lipid peroxidation in vivo in rats with chronic dietary iron overload is dependent on hepatic iron concentration

1 reference

12 December 2020

Carbon tetrachloride and bromotrichloromethane toxicity. Dual role of covalent binding of metabolic cleavage products and lipid peroxidation in depression of microsomal calcium sequestration

1 reference

12 December 2020

Lipid peroxidation and the degradation of cytochrome P-450 heme

1 reference

12 December 2020

Lipid peroxidation products mediate the formation of 8-hydroxydeoxyguanosine in DNA

1 reference

12 December 2020

Cohort study of internal malignancy in genetic hemochromatosis and other chronic nonalcoholic liver diseases

1 reference

12 December 2020

Iron-chelation therapy with oral deferiprone--toxicity or lack of efficacy?

1 reference

12 December 2020

Iron loading of cultured cardiac myocytes modifies sarcolemmal structure and increases lysosomal fragility

1 reference

12 December 2020

Low vitamin E content in plasma of patients with alcoholic liver disease, hemochromatosis and Wilson's disease

1 reference

12 December 2020

Single-strand breaks in DNA of various organs of mice induced by methyl methanesulfonate and dimethylsulfoxide determined by the alkaline unwinding technique

1 reference

12 December 2020

Hemoprotein catabolism during stimulation of microsomal lipid peroxidation

1 reference

12 December 2020

Hepatic mitochondrial malondialdehyde metabolism in rats with chronic iron overload.

1 reference

12 December 2020

Iron-induced tissue damage and cancer: the role of reactive oxygen species-free radicals

1 reference

12 December 2020

Perturbation in liver mitochondrial Ca2+ homeostasis in experimental iron overload: a possible factor in cell injury

1 reference

12 December 2020

Hepatic lipid peroxidation in hereditary hemochromatosis and alcoholic liver injury

1 reference

12 December 2020

Iron deficiency and iron excess damage mitochondria and mitochondrial DNA in rats.

1 reference

12 December 2020

Long-term safety and effectiveness of iron-chelation therapy with deferiprone for thalassemia major

1 reference

12 December 2020

Hepatic microsomal function in rats with chronic dietary iron overload

1 reference

12 December 2020

The pathology of hepatic iron overload: a free radical--mediated process?

1 reference

12 December 2020

Biliary excretion of iron from hepatocyte lysosomes in the rat. A major excretory pathway in experimental iron overload

1 reference

12 December 2020

Levels of malondialdehyde production in rat liver following loading and unloading with iron

1 reference

12 December 2020

Toxic DNA damage by hydrogen peroxide through the Fenton reaction in vivo and in vitro

1 reference

12 December 2020

Oxidative stress and antioxidant status in beta-thalassemia major: iron overload and depletion of lipid-soluble antioxidants

1 reference

12 December 2020

Hereditary hemochromatosis and iron overload diseases

1 reference

12 December 2020

Molecular medicine and hemochromatosis: at the crossroads

1 reference

12 December 2020

Combined therapy with deferiprone and desferrioxamine

1 reference

12 December 2020

Evidence for mitochondrial DNA damage by lipid peroxidation

1 reference

12 December 2020

Molecular bases of cellular iron toxicity

1 reference

12 December 2020

Association of DNA strand breaks with accelerated terminal differentiation in mouse epidermal cells exposed to tumor promoters

1 reference

12 December 2020

Vitamin E inhibits apoptosis, DNA modification, and cancer incidence induced by iron-mediated peroxidation in Wistar rat kidney.

1 reference

12 December 2020

Ferric iron and superoxide ions are required for the killing of cultured hepatocytes by hydrogen peroxide. Evidence for the participation of hydroxyl radicals formed by an iron-catalyzed Haber-Weiss reaction.

1 reference

12 December 2020

Effects of vitamin E deficiency on hepatic mitochondrial lipid peroxidation and oxidative metabolism in rats with chronic dietary iron overload

1 reference

12 December 2020

Isolation of two lysosomal populations from iron-overloaded rat liver with different iron concentration and proteolytic activity

1 reference

12 December 2020

Effect of hemochromatosis on hepatic cytochrome P450 and antipyrine metabolism in humans

1 reference

12 December 2020

Antioxidant status and lipid peroxidation in hereditary haemochromatosis

1 reference

12 December 2020

Acid Hydrolase Activities and Lysosomal Integrity in Liver Biopsies from Patients with Iron Overload

1 reference

12 December 2020

Lipid peroxidation-induced etheno-DNA adducts in the liver of patients with the genetic metal storage disorders Wilson's disease and primary hemochromatosis.

1 reference

12 December 2020

Iron-induced carcinogenesis: the role of redox regulation

1 reference

12 December 2020

Metal-induced hepatotoxicity

1 reference

12 December 2020

Detection of bulky DNA lesions in the liver of patients with Wilson's disease and primary haemochromatosis

1 reference

12 December 2020

Induction of 8-hydroxydeoxyguanosine in Ah-responsive mouse liver by iron and Aroclor 1254

1 reference

12 December 2020

Iron overload and lysosomal stability in beta zero-thalassaemia intermedia and trait: correlation between serum ferritin and serum N-acetyl-beta-D-glucosaminidase levels

1 reference

12 December 2020

Pathophysiology of iron overload.

1 reference

12 December 2020

Hemochromatosis: diagnosis and management

1 reference

12 December 2020

Increased p53 mutation load in nontumorous human liver of wilson disease and hemochromatosis: oxyradical overload diseases

1 reference

12 December 2020

Ethane exhalation and vitamin E/ubiquinol status as markers of lipid peroxidation in ferrocene iron-loaded rats

1 reference

12 December 2020

Alterations in the structure, physicochemical properties, and pH of hepatocyte lysosomes in experimental iron overload

1 reference

12 December 2020

Intracellular calcium homeostasis

1 reference

12 December 2020

Effects of iron loading on free radical scavenging enzymes and lipid peroxidation in rat liver

1 reference

12 December 2020

Induction of oxidative single- and double-strand breaks in DNA by ferric citrate.

1 reference

12 December 2020

Deleterious iron-mediated oxidation of biomolecules

1 reference

12 December 2020

Studies on the rat liver following iron overload: biochemical studies after iron mobilization

1 reference

12 December 2020

Effect of dietary iron overload on lipid peroxidation, prostaglandin synthesis and lymphocyte proliferation in young and old rats

1 reference

12 December 2020

Vitamin E decreases hepatic levels of aldehyde-derived peroxidation products in rats with iron overload.

1 reference

12 December 2020

Oral iron chelation therapy for thalassaemia: an uncertain scene

1 reference

12 December 2020

Iron-induced peroxidative injury to isolated rat hepatic mitochondria

1 reference

12 December 2020

Morphologic observations in iron overload: an update

1 reference

12 December 2020

Hepatic lipid peroxidation in vivo in rats with chronic iron overload

1 reference

12 December 2020

Identification of thiolic sarcolemmal proteins as a primary target of iron toxicity in cultured heart cells

1 reference

12 December 2020

Misreading of DNA templates containing 8-hydroxydeoxyguanosine at the modified base and at adjacent residues

1 reference

12 December 2020

Iron chelators for thalassaemia

1 reference

12 December 2020

Antioxidant activity of silybin in vivo during long-term iron overload in rats

1 reference

12 December 2020

Role of free radicals and catalytic metal ions in human disease: an overview

1 reference

12 December 2020

Rapid in vitro transformation system for liver epithelial cells by iron chelate, Fe-NTA

1 reference

12 December 2020

Iron supplementation generates hydroxyl radical in vivo. An ESR spin-trapping investigation

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF02982791

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Dimensions Publication ID

29 July 2017

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1 reference