(Q33849727)

29 July 2017

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title

The multiple roles of PTEN in tumor suppression (English)

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29 July 2017

A Di Cristofano

1

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29 July 2017

P P Pandolfi

series ordinal

2

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29 July 2017

language of work or name

English

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publication date

1 February 2000

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29 July 2017

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29 July 2017

volume

100

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29 July 2017

issue

4

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29 July 2017

page(s)

387-390

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New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

29 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980674-1

7 January 2021

Cellular survival: a play in three Akts

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980674-1

7 January 2021

Impaired Fas response and autoimmunity in Pten+/- mice

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980674-1

7 January 2021

Pten is essential for embryonic development and tumour suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980674-1

7 January 2021

The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980674-1

7 January 2021

Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980674-1

7 January 2021

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980674-1

7 January 2021

The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980674-1

7 January 2021

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980674-1

7 January 2021

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980674-1

7 January 2021

PTEN tumour suppressor is linked to the cell cycle control through the retinoblastoma protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980674-1

7 January 2021

Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980674-1

7 January 2021

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980674-1

7 January 2021

PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980674-1

7 January 2021

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980674-1

7 January 2021

PTEN gene and integrin signaling in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2800%2980674-1

7 January 2021

10.1016/S0092-8674(00)80674-1

Identifiers

DOI

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29 July 2017

1 reference