(Q33855053)

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Association study of the let-7 miRNA-complementary site variant in the 3' untranslated region of the KRAS gene in stage III colon cancer (NCCTG N0147 Clinical Trial).

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Europe PubMed Central

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29 July 2017

Association study of the let-7 miRNA-complementary site variant in the 3' untranslated region of the KRAS gene in stage III colon cancer (NCCTG N0147 Clinical Trial). (English)

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29 July 2017

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Dan Sha

1

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Europe PubMed Central

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13 June 2020

Adam M Lee

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24727325%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Qian Shi

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24727325%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Frank A Sinicrope

6

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13 June 2020

Robert B Diasio

7

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13 June 2020

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11 April 2014

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29 July 2017

Clinical Cancer Research

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13 June 2020

20

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13 June 2020

12

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13 June 2020

3319-3327

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24727325%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Prognostic impact of deficient DNA mismatch repair in patients with stage III colon cancer from a randomized trial of FOLFOX-based adjuvant chemotherapy

1 reference

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Colorectal carcinomas with KRAS mutation are associated with distinctive morphological and molecular features

1 reference

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Let-7 miRNA-binding site polymorphism in the KRAS 3'UTR; colorectal cancer screening population prevalence and influence on clinical outcome in patients with metastatic colorectal cancer treated with 5-fluorouracil and oxaliplatin +/- cetuximab

1 reference

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KRAS-LCS6 genotype as a prognostic marker in early-stage CRC--letter

1 reference

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Effect of oxaliplatin, fluorouracil, and leucovorin with or without cetuximab on survival among patients with resected stage III colon cancer: a randomized trial

1 reference

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Cancer statistics, 2012

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Perspectives on current tumor-node-metastasis (TNM) staging of cancers of the colon and rectum

1 reference

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Metastatic colorectal cancer KRAS genotyping in routine practice: results and pitfalls

1 reference

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A 3'-untranslated region KRAS variant and triple-negative breast cancer: a case-control and genetic analysis

1 reference

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The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing

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Global cancer statistics

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A let-7 microRNA-binding site polymorphism in 3'-untranslated region of KRAS gene predicts response in wild-type KRAS patients with metastatic colorectal cancer treated with cetuximab monotherapy

1 reference

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Genetic modulation of the Let-7 microRNA binding to KRAS 3'-untranslated region and survival of metastatic colorectal cancer patients treated with salvage cetuximab-irinotecan

1 reference

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28 July 2018

KRAS mutation, KRAS-LCS6 polymorphism, and non-small cell lung cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084689

28 July 2018

KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084689

28 July 2018

A let-7 microRNA-binding site polymorphism in the KRAS 3' UTR is associated with reduced survival in oral cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084689

28 July 2018

A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084689

28 July 2018

The let-7 microRNA reduces tumor growth in mouse models of lung cancer

1 reference

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A microRNA component of the p53 tumour suppressor network

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Colorectal cancer model of health disparities: understanding mortality differences in minority populations

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28 July 2018

let-7 microRNA functions as a potential growth suppressor in human colon cancer cells

1 reference

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Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution

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MicroRNA gene expression deregulation in human breast cancer

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MicroRNA expression profiles classify human cancers

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RAS is regulated by the let-7 microRNA family

1 reference

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Cancer statistics, 2005

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084689

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The functions of animal microRNAs

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Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival

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Micro RNAs are complementary to 3' UTR sequence motifs that mediate negative post-transcriptional regulation

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DNA damage promotes jumping between templates during enzymatic amplification

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The LCS6 polymorphism in the binding site of let-7 microRNA to the KRAS 3'-untranslated region: its role in the efficacy of anti-EGFR-based therapy in metastatic colorectal cancer patients

1 reference

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A let-7 microRNA SNP in the KRAS 3'UTR is prognostic in early-stage colorectal cancer

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K-ras mutations and benefit from cetuximab in advanced colorectal cancer.

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10.1158/1078-0432.CCR-14-0069

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24727325%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

PMC publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24727325%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24727325%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

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