(Q33855451)

29 July 2017

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title

Epigenetic aspects of cellular senescence (English)

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29 July 2017

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Young J

1

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29 July 2017

Smith JR

series ordinal

2

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29 July 2017

publication date

1 February 2000

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29 July 2017

published in

Experimental Gerontology

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29 July 2017

volume

35

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29 July 2017

issue

1

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29 July 2017

page(s)

23-32

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The growth arrest and downregulation of c-myc transcription induced by ceramide are related events dependent on p21 induction, Rb underphosphorylation and E2F sequestering

29 July 2017

cites work

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7 January 2021

Identification of a gene that reverses the immortal phenotype of a subset of cells and is a member of a novel family of transcription factor-like genes

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7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

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7 January 2021

Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts

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7 January 2021

Two posttranscriptional pathways that regulate p21(Cip1/Waf1/Sdi1) are identified by HPV16-E6 interaction and correlate with life span and cellular senescence.

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7 January 2021

The biology of replicative senescence

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7 January 2021

DNA demethylase is a processive enzyme

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7 January 2021

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

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7 January 2021

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

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7 January 2021

The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine-induced demethylation

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7 January 2021

Reinitiation of DNA synthesis and cell division in senescent human fibroblasts by microinjection of anti-p53 antibodies

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7 January 2021

The Werner syndrome protein is a DNA helicase

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7 January 2021

Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD.

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7 January 2021

Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence

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7 January 2021

Telomeres shorten during ageing of human fibroblasts

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7 January 2021

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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7 January 2021

The serial cultivation of human diploid cell strains

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7 January 2021

p16(INK4a) and the control of cellular proliferative life span.

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7 January 2021

Evidence for a p53‐independent pathway for upregulation of SDI1/CIP1/WAF1/P21 RNA in human cells

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7 January 2021

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

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7 January 2021

Effects of hypoxia and fasting on the cytochrome concentration in intestinal epithelial villous cell mitochondria. Role of changes in the life-span of the cells.

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7 January 2021

Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

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7 January 2021

p53, the cellular gatekeeper for growth and division

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7 January 2021

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

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7 January 2021

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

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https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900076-5

7 January 2021

Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts

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7 January 2021

DNA topoisomerase inhibitors induce reversible senescence in normal human fibroblasts

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7 January 2021

Ras signalling is required for inactivation of the tumour suppressor pRb cell-cycle control protein

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7 January 2021

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen

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7 January 2021

Murine fibroblasts lacking p21 undergo senescence and are resistant to transformation by oncogenic Ras.

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7 January 2021

p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells

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7 January 2021

Preferential accumulation of single-stranded regions in telomeres of human fibroblasts

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https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900076-5

7 January 2021

Agents that cause DNA double strand breaks lead to p16INK4a enrichment and the premature senescence of normal fibroblasts

1 reference

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7 January 2021

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

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7 January 2021

Loss of a yeast telomere: arrest, recovery, and chromosome loss.

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7 January 2021

1 reference

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7 January 2021

DNA methylation in aging of mice

1 reference

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7 January 2021

DNA methyltransferase is a downstream effector of cellular transformation triggered by simian virus 40 large T antigen

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7 January 2021

Replicative senescence: implications for in vivo aging and tumor suppression

1 reference

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7 January 2021

Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900076-5

7 January 2021

From telomere loss to p53 induction and activation of a DNA-damage pathway at senescence: the telomere loss/DNA damage model of cell aging

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900076-5

7 January 2021

Role of ceramide in cellular senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900076-5

7 January 2021

Mild Hyperoxia Shortens Telomeres and Inhibits Proliferation of Fibroblasts: A Model for Senescence?

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900076-5

7 January 2021

Ceramide activates the stress-activated protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900076-5

7 January 2021

DNA methylation decreases in aging but not in immortal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900076-5

7 January 2021

Direct activation of TERT transcription by c-MYC.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900076-5

7 January 2021

Senescence of human fibroblasts induced by oncogenic Raf.

1 reference

https://api.crossref.org/works/10.1016%2FS0531-5565%2899%2900076-5

7 January 2021

10.1016/S0531-5565(99)00076-5

Identifiers

DOI

1 reference

29 July 2017

1 reference