(Q33855576)

29 July 2017

title

The Notch-2 gene is regulated by Wnt signaling in cultured colorectal cancer cells (English)

1 reference

29 July 2017

1 reference

1 reference

John Grünberg

3

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Mikael Sigvardsson

object named as

Mikael Sigvardsson

4

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author name string

Jonas Ungerbäck

1

1 reference

29 July 2017

Nils Elander

2

1 reference

29 July 2017

Peter Söderkvist

5

1 reference

29 July 2017

language of work or name

English

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publication date

18 March 2011

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29 July 2017

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29 July 2017

volume

6

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29 July 2017

issue

3

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29 July 2017

page(s)

e17957

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Complex interplay between β-catenin signalling and Notch effectors in intestinal tumorigenesis

29 July 2017

cites work

1 reference

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NOTCH signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer

28 July 2018

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Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer

28 July 2018

1 reference

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Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine

28 July 2018

1 reference

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Beta-catenin modulates the level and transcriptional activity of Notch1/NICD through its direct interaction

28 July 2018

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Stabilized beta-catenin functions through TCF/LEF proteins and the Notch/RBP-Jkappa complex to promote proliferation and suppress differentiation of neural precursor cells.

28 July 2018

1 reference

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Numb mediates the interaction between Wnt and Notch to modulate primitive erythropoietic specification from the hemangioblast

28 July 2018

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28 July 2018

The intestinal stem cell

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Genetic deletion of mPGES-1 accelerates intestinal tumorigenesis in APC(Min/+) mice

28 July 2018

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28 July 2018

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Crosstalk between Wnt and Notch signaling in intestinal epithelial cell fate decision.

28 July 2018

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28 July 2018

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Jagged 1 is a beta-catenin target gene required for ectopic hair follicle formation in adult epidermis

28 July 2018

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28 July 2018

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The APC tumor suppressor counteracts beta-catenin activation and H3K4 methylation at Wnt target genes

28 July 2018

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Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism

28 July 2018

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Notch and Wnt inhibitors as potential new drugs for intestinal neoplastic disease

28 July 2018

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Loss of adenomatous polyposis coli gene function disrupts thymic development

28 July 2018

1 reference

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p21WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation

28 July 2018

1 reference

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Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

28 July 2018

1 reference

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MatInspector and beyond: promoter analysis based on transcription factor binding sites

28 July 2018

1 reference

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Wnt signalling in stem cells and cancer

28 July 2018

1 reference

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LEF1-mediated regulation of Delta-like1 links Wnt and Notch signaling in somitogenesis

28 July 2018

1 reference

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WNT signaling, in synergy with T/TBX6, controls Notch signaling by regulating Dll1 expression in the presomitic mesoderm of mouse embryos

28 July 2018

1 reference

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The Wnt signaling pathway in development and disease

28 July 2018

1 reference

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Notch signaling: the demise of elegant simplicity

28 July 2018

1 reference

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Hath1, down-regulated in colon adenocarcinomas, inhibits proliferation and tumorigenesis of colon cancer cells

28 July 2018

1 reference

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Notch and epithelial-mesenchyme transition in development and tumor progression: another turn of the screw.

28 July 2018

1 reference

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Canonical Wnt signals are essential for homeostasis of the intestinal epithelium

28 July 2018

1 reference

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Notch1 functions as a tumor suppressor in mouse skin

28 July 2018

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Cloning and characterization of a promoter flanking the early B cell factor (EBF) gene indicates roles for E-proteins and autoregulation in the control of EBF expression

28 July 2018

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Requirement of Math1 for secretory cell lineage commitment in the mouse intestine

28 July 2018

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Synergy between tumor suppressor APC and the beta-catenin-Tcf4 target Tcf1.

28 July 2018

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Hey genes: a novel subfamily of hairy- and Enhancer of split related genes specifically expressed during mouse embryogenesis

28 July 2018

1 reference

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The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

28 July 2018

1 reference

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Notch signaling: cell fate control and signal integration in development

28 July 2018

1 reference

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beta-catenin is a target for the ubiquitin-proteasome pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060910

Fringe boundaries coincide with Notch-dependent patterning centres in mammals and alter Notch-dependent development in Drosophila

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060910

A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060910

Studies of neoplasia in the Min mouse

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060910

Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060910

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060910

Nuclear localization of beta-catenin by interaction with transcription factor LEF-1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060910

Functional interaction of beta-catenin with the transcription factor LEF-1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060910

XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060910

Apoptosis and APC in colorectal tumorigenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060910

Constitutively active human Notch1 binds to the transcription factor CBF1 and stimulates transcription through a promoter containing a CBF1-responsive element

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060910

Binding of GSK3beta to the APC-beta-catenin complex and regulation of complex assembly

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060910

Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060910

MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060910

Signalling downstream of activated mammalian Notch

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060910

A genetic model for colorectal tumorigenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060910

Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2.

28 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017957

Organizing cell renewal in the intestine: stem cells, signals and combinatorial control

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017957

Signaling pathways in intestinal development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017957

Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017957

Glycosylation regulates Notch signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017957

bHLH proteins encoded by the Enhancer of split complex of Drosophila negatively interfere with transcriptional activation mediated by proneural genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017957

HMG box containing transcription factors in lymphocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017957

Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017957

Notch modulates Wnt signalling by associating with Armadillo/beta-catenin and regulating its transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017957

Activation of Notch signaling in human colon adenocarcinoma

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060910

Beta-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060910

Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060910

Expression of Notch pathway genes in mammalian epidermis and modulation by β-Catenin

29 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017957

Notch signals control the fate of immature progenitor cells in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0017957

Notch2 expression is decreased in colorectal cancer and related to tumor differentiation status

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21437251

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0017957

1 reference

29 July 2017

0 references

1 reference

29 July 2017

1 reference