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A peptide prime-DNA boost immunization protocol provides significant benefits as a new generation Aβ42 DNA vaccine for Alzheimer disease.
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
4084825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
title
A peptide prime-DNA boost immunization protocol provides significant benefits as a new generation Aβ42 DNA vaccine for Alzheimer disease
(English)
1 reference
stated in
Europe PubMed Central
PMCID
4084825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
main subject
Alzheimer's disease
0 references
immunization
0 references
author
Doris Lambracht-Washington
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
4084825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Larry D Anderson
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
4084825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Todd Eagar
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMCID
4084825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
author name string
Bao-xi Qu
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
4084825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Min Fu
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
4084825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Roger N Rosenberg
series ordinal
7
1 reference
stated in
Europe PubMed Central
PMCID
4084825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
Olaf Stüve
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMCID
4084825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
publication date
1 October 2012
1 reference
stated in
Europe PubMed Central
PMCID
4084825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
published in
Journal of Neuroimmunology
1 reference
stated in
Europe PubMed Central
PMCID
4084825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
volume
254
1 reference
stated in
Europe PubMed Central
PMCID
4084825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
issue
1-2
1 reference
stated in
Europe PubMed Central
PMCID
4084825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
page(s)
63-68
1 reference
stated in
Europe PubMed Central
PMCID
4084825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
cites work
DNA immunization against amyloid beta 42 has high potential as safe therapy for Alzheimer's disease as it diminishes antigen-specific Th1 and Th17 cell proliferation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
5 July 2018
Analysis of three plasmid systems for use in DNA A beta 42 immunization as therapy for Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
5 July 2018
Beneficial effect of human anti-amyloid-beta active immunization on neurite morphology and tau pathology
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
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5 July 2018
Can Alzheimer disease be prevented by amyloid-beta immunotherapy?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
5 July 2018
DNA prime-protein boost increased the titer, avidity and persistence of anti-Abeta antibodies in wild-type mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
5 July 2018
DNA beta-amyloid(1-42) trimer immunization for Alzheimer disease in a wild-type mouse model.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
5 July 2018
Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
5 July 2018
Reducing AD-like pathology in 3xTg-AD mouse model by DNA epitope vaccine - a novel immunotherapeutic strategy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
5 July 2018
Enhancing Th2 immune responses against amyloid protein by a DNA prime-adenovirus boost regimen for Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
5 July 2018
Abeta42 gene vaccine prevents Abeta42 deposition in brain of double transgenic mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
5 July 2018
Abeta42 gene vaccination reduces brain amyloid plaque burden in transgenic mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
5 July 2018
Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
5 July 2018
Gene vaccination to bias the immune response to amyloid-beta peptide as therapy for Alzheimer disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
5 July 2018
Jump-starting the immune system: prime-boosting comes of age.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
5 July 2018
Epitope and isotype specificities of antibodies to beta -amyloid peptide for protection against Alzheimer's disease-like neuropathology
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
5 July 2018
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
5 July 2018
A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
5 July 2018
Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
5 July 2018
New insights into the genetics of Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
5 July 2018
Amyloid beta-protein and the genetics of Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
5 July 2018
Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
5 July 2018
Neutralization of soluble, synaptotoxic amyloid β species by antibodies is epitope specific.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
29 October 2018
Reduced oligomeric and vascular amyloid-beta following immunization of TgCRND8 mice with an Alzheimer's DNA vaccine.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
29 October 2018
Enhanced Th2 immunity after DNA prime-protein boost immunization with amyloid beta (1-42) plus CpG oligodeoxynucleotides in aged rats.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
29 October 2018
Beta-amyloid immunotherapy prevents synaptic degeneration in a mouse model of Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
29 October 2018
Effects of Abeta immunization (AN1792) on MRI measures of cerebral volume in Alzheimer disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
29 October 2018
Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
29 October 2018
A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4084825
retrieved
29 October 2018
Th1 and Th2 CD4+ T cells provide help for B cell clonal expansion and antibody synthesis in a similar manner in vivo
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/23036592
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.JNEUROIM.2012.09.008
1 reference
stated in
Europe PubMed Central
PMCID
4084825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
PMCID
4084825
1 reference
stated in
Europe PubMed Central
PMCID
4084825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
PubMed ID
23036592
1 reference
stated in
Europe PubMed Central
PMCID
4084825
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23036592%20AND%20SRC:MED&resulttype=core&format=json
retrieved
9 March 2020
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