(Q33856313)

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Manganese upregulates cellular prion protein and contributes to altered stabilization and proteolysis: relevance to role of metals in pathogenesis of prion disease

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 July 2017

Manganese upregulates cellular prion protein and contributes to altered stabilization and proteolysis: relevance to role of metals in pathogenesis of prion disease (English)

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Europe PubMed Central

PubMed publication ID

29 July 2017

prion protein family

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1 reference

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Jürgen A. Richt

5

object named as

Jürgen A Richt

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Europe PubMed Central

PubMed publication ID

29 July 2017

author name string

Christopher J Choi

1

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Europe PubMed Central

PubMed publication ID

29 July 2017

Vellareddy Anantharam

2

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Europe PubMed Central

PubMed publication ID

29 July 2017

Dustin P Martin

3

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Eric M Nicholson

4

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Europe PubMed Central

PubMed publication ID

29 July 2017

Arthi Kanthasamy

6

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Europe PubMed Central

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29 July 2017

Anumantha G Kanthasamy

7

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Europe PubMed Central

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29 July 2017

publication date

22 February 2010

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Europe PubMed Central

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29 July 2017

Toxicological Sciences

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Europe PubMed Central

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29 July 2017

115

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Europe PubMed Central

PubMed publication ID

29 July 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

535-546

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2871751/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Age-dependent susceptibility to manganese-induced neurological dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Is Parkinson's disease a prion disorder?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Oxidative damage and neurodegeneration in manganese-induced neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Prion protein (PrP) knock-out mice show altered iron metabolism: a functional role for PrP in iron uptake and transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Brain proteins that mind metals: a neurodegenerative perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

From cell protection to death: may Ca2+ signals explain the chameleonic attributes of the mammalian prion protein?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Mechanism of the metal-mediated endocytosis of the prion protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Opposing roles of prion protein in oxidative stress- and ER stress-induced apoptotic signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Antioxidants prevent the cytotoxicity of manganese in RBE4 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Prion strain discrimination in cell culture: the cell panel assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Normal cellular prion protein protects against manganese-induced oxidative stress and apoptotic cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Production of cattle lacking prion protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Pathogenesis of prion diseases: current status and future outlook

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Interaction of metals with prion protein: possible role of divalent cations in the pathogenesis of prion diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Octapeptide repeat insertions increase the rate of protease-resistant prion protein formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Dieldrin induces ubiquitin-proteasome dysfunction in alpha-synuclein overexpressing dopaminergic neuronal cells and enhances susceptibility to apoptotic cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Molecular neurology of prion disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Protein kinase Cdelta is a key downstream mediator of manganese-induced apoptosis in dopaminergic neuronal cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Calpain and other cytosolic proteases can contribute to the degradation of retro-translocated prion protein in the cytosol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Cellular prion protein transduces neuroprotective signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Consequences of manganese replacement of copper for prion protein function and proteinase resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Prion protein and the scrapie agent: in vitro studies in infected neuroblastoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Biohazards of Investigations on the Transmissible Spongiform Encephalopathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Prions--infectious pathogens causing the spongiform encephalopathies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Chronic manganese intoxication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Manganese induced parkinsonism: an outbreak due to an unrepaired ventilation control system in a ferromanganese smelter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

5 July 2018

Octarepeat changes of prion protein in Parkinson's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

29 October 2018

Effect of copper and manganese on the de novo generation of protease-resistant prion protein in yeast cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

29 October 2018

Copper(II) inhibits in vitro conversion of prion protein into amyloid fibrils.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

29 October 2018

Copper binding to prion octarepeat peptides, a combined metal chelate affinity and immunochemical approaches

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

29 October 2018

Calpain-dependent endoproteolytic cleavage of PrPSc modulates scrapie prion propagation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

29 October 2018

Conversion of PrP to a self-perpetuating PrPSc-like conformation in the cytosol

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

29 October 2018

Copper binding to the N-terminal tandem repeat regions of mammalian and avian prion protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2871751

29 October 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/20176619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human prion diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/20176619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/20176619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DMT1: which metals does it transport?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20176619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Manganese binding to the prion protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/20176619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurodegeneration. Acting like a prion isn't always bad

1 reference

https://pubmed.ncbi.nlm.nih.gov/20176619

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/TOXSCI/KFQ049

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

ResearchGate publication ID

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