(Q33858160)

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Overexpression of urokinase by plaque macrophages causes histological features of plaque rupture and increases vascular matrix metalloproteinase activity in aged apolipoprotein e-null mice

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29 January 2020

Overexpression of urokinase by plaque macrophages causes histological features of plaque rupture and increases vascular matrix metalloproteinase activity in aged apolipoprotein e-null mice (English)

1 reference

Europe PubMed Central

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29 January 2020

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6

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29 January 2020

David A. Dichek

9

object named as

David A Dichek

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29 January 2020

Nagadhara Dronadula

5

object named as

Nagadhara Dronadula

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29 January 2020

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Jie Hong Hu

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29 January 2020

Liang Du

2

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29 January 2020

Talyn Chu

3

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29 January 2020

Goro Otsuka

4

1 reference

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29 January 2020

Sean E Gill

7

1 reference

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29 January 2020

William C Parks

8

1 reference

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29 January 2020

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29 March 2010

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29 January 2020

1 reference

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29 January 2020

121

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29 January 2020

14

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29 January 2020

1637-1644

1 reference

Europe PubMed Central

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29 January 2020

Level of macrophage uPA expression is an important determinant of atherosclerotic lesion growth in Apoe-/- mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

Plasminogen mediates the atherogenic effects of macrophage-expressed urokinase and accelerates atherosclerosis in apoE-knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

Inflammatory macrophage migration requires MMP-9 activation by plasminogen in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

The molecular mechanisms of the thrombotic complications of atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

From vulnerable plaque to atherothrombosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

Translating molecular discoveries into new therapies for atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

Type 1 diabetes promotes disruption of advanced atherosclerotic lesions in LDL receptor-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

Metalloproteinases and vulnerable atherosclerotic plaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

Molecular mechanisms of plaque instability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

Control of matrix metalloproteinase catalytic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

Animal models to study plaque vulnerability.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

The emerging role of vascular smooth muscle cell apoptosis in atherosclerosis and plaque stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

Macrophage expression of active MMP-9 induces acute plaque disruption in apoE-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

The role of shear stress in the destabilization of vulnerable plaques and related therapeutic implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

Proteolysis of the pericellular matrix: a novel element determining cell survival and death in the pathogenesis of plaque erosion and rupture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

The unstable plaque.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

Increased expression of urokinase during atherosclerotic lesion development causes arterial constriction and lumen loss, and accelerates lesion growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

Atherosclerotic plaque rupture in the apolipoprotein E knockout mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

Mechanisms of progression in native coronary artery disease: role of healed plaque disruption.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

Fibrinolytic activation markers predict myocardial infarction in the elderly. The Cardiovascular Health Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

Matrilysin is expressed by lipid-laden macrophages at sites of potential rupture in atherosclerotic lesions and localizes to areas of versican deposition, a proteoglycan substrate for the enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

Characterization of recombinant plasminogen activator production by primate endothelial cells transduced with retroviral vectors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

92-kd gelatinase is actively expressed by eosinophils and stored by neutrophils in squamous cell carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

Coronary plaque disruption.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

5 July 2018

Vulnerable atherosclerotic plaque metalloproteinases and foam cell phenotypes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

29 October 2018

Elevated tissue expression of thrombomodulatory factors correlates with acute symptomatic carotid plaque phenotype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

29 October 2018

Urokinase-type plasminogen activator receptor is associated with macrophages and plaque rupture in symptomatic carotid atherosclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

29 October 2018

Carotid plaque instability and ischemic symptoms are linked to immaturity of microvessels within plaques.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

29 October 2018

Haemostatic factors and the risk of cardiovascular death in patients with coronary artery disease: the AtheroGene study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

29 October 2018

Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

29 October 2018

Atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

29 October 2018

Mechanisms of cardiac fibrosis induced by urokinase plasminogen activator.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

29 October 2018

Macrophage-targeted overexpression of urokinase causes accelerated atherosclerosis, coronary artery occlusions, and premature death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

29 October 2018

Association between plasmin activation system and intravascular ultrasound signs of plaque instability in patients with unstable angina and non-st-segment elevation myocardial infarction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872172

29 October 2018

Advanced atherosclerotic lesions in the innominate artery of the ApoE knockout mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/20351234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prospective study of fibrinolytic factors and incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20351234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasmin and matrix metalloproteinases in vascular remodeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/20351234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LPS induced procoagulant activity and plasminogen activator activity in mononuclear cells from persons with high or low levels of HDL lipoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/20351234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasminogen activator expression in human atherosclerotic lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/20351234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation of urokinase-type plasminogen activator expression to presence and severity of atherosclerotic lesions in human coronary arteries

1 reference

https://pubmed.ncbi.nlm.nih.gov/20351234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urokinase plasminogen activator colocalizes with CD25+ cells in atherosclerotic vessels

1 reference

https://pubmed.ncbi.nlm.nih.gov/20351234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lesional overexpression of matrix metalloproteinase-9 promotes intraplaque hemorrhage in advanced lesions but not at earlier stages of atherogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20351234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Topology of protease activities reflects atherothrombotic plaque complexity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20351234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of urokinase plasminogen activator promotes progression and instability of atherosclerotic lesions in apolipoprotein E-knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20351234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased endoplasmic reticulum stress in atherosclerotic plaques associated with acute coronary syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/20351234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arterial blood pressure gradient across vulnerable plaque might increase rupture

1 reference

https://pubmed.ncbi.nlm.nih.gov/20351234

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1161/CIRCULATIONAHA.109.914945

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20351234%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20351234%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20351234%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

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