(Q33860499)

29 July 2017

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title

Signalling through the insulin receptor (English)

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29 July 2017

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Whitehead JP

1

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29 July 2017

Clark SF

series ordinal

2

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29 July 2017

Urso B

series ordinal

3

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29 July 2017

James DE

series ordinal

4

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29 July 2017

language of work or name

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1 April 2000

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Current Opinion in Cell Biology

29 July 2017

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29 July 2017

12

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29 July 2017

2

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29 July 2017

222-228

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The IRS-signalling system: a network of docking proteins that mediate insulin action

29 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Mechanism of activation and function of protein kinase B.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Insulin receptor substrate-2 (IRS-2) can mediate the action of insulin to stimulate translocation of GLUT4 to the cell surface in rat adipose cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

The akt kinase: molecular determinants of oncogenicity

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Akt is more than just a Bad kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Characterization of an interaction between insulin receptor substrate 1 and the insulin receptor by using the two-hybrid system

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

The pleckstrin homology domain is the principal link between the insulin receptor and IRS-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Insulin receptor substrate-2 binds to the insulin receptor through its phosphotyrosine-binding domain and through a newly identified domain comprising amino acids 591-786

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Interaction of insulin receptor substrate-2 (IRS-2) with the insulin and insulin-like growth factor I receptors. Evidence for two distinct phosphotyrosine-dependent interaction domains within IRS-2

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

IRS pleckstrin homology domains bind to acidic motifs in proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Cloning, tissue expression, and chromosomal location of the mouse insulin receptor substrate 4 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Different subcellular distribution and regulation of expression of insulin receptor substrate (IRS)-3 from those of IRS-1 and IRS-2

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Insulin receptor substrate 3 is not essential for growth or glucose homeostasis.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Disruption of IRS-2 causes type 2 diabetes in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

The Drosophila insulin receptor homolog: a gene essential for embryonic development encodes two receptor isoforms with different signaling potential.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Comparison of the signaling abilities of the Drosophila and human insulin receptors in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

The carboxyl terminal extension of the Drosophila insulin receptor homologue binds IRS-1 and influences cell survival

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Annexin II is a novel player in insulin signal transduction. Possible association between annexin II phosphorylation and insulin receptor internalization.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Insulin Regulation of Membrane-associated Insulin Receptor Substrate 1

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Inhibition of clathrin-mediated endocytosis selectively attenuates specific insulin receptor signal transduction pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Dynamics of insulin signaling in 3T3-L1 adipocytes. Differential compartmentalization and trafficking of insulin receptor substrate (IRS)-1 and IRS-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Intracellular localization of phosphatidylinositide 3-kinase and insulin receptor substrate-1 in adipocytes: potential involvement of a membrane skeleton

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Release of insulin receptor substrate proteins from an intracellular complex coincides with the development of insulin resistance.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Insulin-regulatable phosphoproteins in 3T3-L1 adipocytes form detergent-insoluble complexes not associated with caveolin

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Formation and contraction of a microfilamentous shell in saponin-permeabilized platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Rearrangement of the vimentin cytoskeleton during adipose conversion: formation of an intermediate filament cage around lipid globules

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Interaction of insulin receptor substrate-1 with the sigma3A subunit of the adaptor protein complex-3 in cultured adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Insulin-dependent translocation of ARNO to the plasma membrane of adipocytes requires phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Role of translocation in the activation and function of protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Insulin-induced translocation of protein kinase B to the plasma membrane in rat adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

A role for protein kinase Bbeta/Akt2 in insulin-stimulated GLUT4 translocation in adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Activation of mitogen-activated protein kinase and phosphatidylinositol 3'-kinase is not sufficient for the hormonal stimulation of glucose uptake, lipogenesis, or glycogen synthesis in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Compartment-specific regulation of phosphoinositide 3-kinase by platelet-derived growth factor and insulin in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Transient effect of platelet-derived growth factor on GLUT4 translocation in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Platelet-derived growth factor inhibits insulin stimulation of insulin receptor substrate-1-associated phosphatidylinositol 3-kinase in 3T3-L1 adipocytes without affecting glucose transport

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

The activation of glycogen synthase by insulin switches from kinase inhibition to phosphatase activation during adipogenesis in 3T3-L1 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Differentiation-dependent suppression of platelet-derived growth factor signaling in cultured adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Bifurcation of lipid and protein kinase signals of PI3Kgamma to the protein kinases PKB and MAPK

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

A molecular basis for insulin resistance. Elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphory

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

The PI3-kinase serine kinase phosphorylates its p85 subunit and IRS-1 in PI3-kinase/IRS-1 complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Modulation of insulin receptor substrate-1 tyrosine phosphorylation by an Akt/phosphatidylinositol 3-kinase pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Modulation of insulin receptor substrate-1 tyrosine phosphorylation and function by mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Phosphorylation of insulin receptor substrate 1 by glycogen synthase kinase 3 impairs insulin action

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

The role of glycogen synthase kinase 3beta in insulin-stimulated glucose metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

A rho-associated protein kinase, ROKalpha, binds insulin receptor substrate-1 and modulates insulin signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

RhoA-binding kinase alpha translocation is facilitated by the collapse of the vimentin intermediate filament network

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Regulation of insulin-stimulated tyrosine phosphorylation of Shc and IRS-1 in the muscle of rats: effect of growth hormone and epinephrine

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Insulin stimulates the degradation of IRS-1 in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Identification of enhanced serine kinase activity in insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Oxidative stress disrupts insulin-induced cellular redistribution of insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-L1 adipocytes. A putative cellular mechanism for impaired protein kinase B activation and GLUT4 translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Insulin-induced insulin receptor substrate-1 degradation is mediated by the proteasome degradation pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Membrane-permeant esters of phosphatidylinositol 3,4,5-trisphosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Protein kinase B/Akt participates in GLUT4 translocation by insulin in L6 myoblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Requirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Effects of transiently expressed atypical (zeta, lambda), conventional (alpha, beta) and novel (delta, epsilon) protein kinase C isoforms on insulin-stimulated translocation of epitope-tagged GLUT4 glucose transporters in rat adipocytes: specific in

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

In vivo adenoviral delivery of recombinant human protein kinase C-zeta stimulates glucose transport activity in rat skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

Confocal imaging of the subcellular distribution of phosphatidylinositol 3,4,5-trisphosphate in insulin- and PDGF-stimulated 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2899%2900079-4

7 January 2021

10.1016/S0955-0674(99)00079-4

Identifiers

DOI

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29 July 2017

1 reference