(Q33864635)

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Identification and characterization of KCASH2 and KCASH3, 2 novel Cullin3 adaptors suppressing histone deacetylase and Hedgehog activity in medulloblastoma.

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21472142%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Identification and characterization of KCASH2 and KCASH3, 2 novel Cullin3 adaptors suppressing histone deacetylase and Hedgehog activity in medulloblastoma (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21472142%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

medulloblastoma

0 references

Potassium channel tetramerization domain containing 6

1 reference

GOA release 2020-03-11

Potassium channel tetramerization domain containing 21

1 reference

GOA release 2020-03-11

cullin family protein binding

1 reference

GOA release 2020-03-11

Enrico De Smaele

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21472142%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Elisabetta Ferretti

13

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27 January 2020

author name string

Lucia Di Marcotullio

2

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27 January 2020

Marta Moretti

3

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27 January 2020

Marianna Pelloni

4

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27 January 2020

Maria Anna Occhione

5

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27 January 2020

Paola Infante

6

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27 January 2020

Danilo Cucchi

7

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27 January 2020

Azzura Greco

8

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27 January 2020

Laura Pietrosanti

9

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27 January 2020

Jelena Todorovic

10

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27 January 2020

Sonia Coni

11

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27 January 2020

Gianluca Canettieri

12

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27 January 2020

Roberto Bei

14

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27 January 2020

Marella Maroder

15

1 reference

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27 January 2020

Isabella Screpanti

16

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21472142%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Alberto Gulino

17

1 reference

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27 January 2020

publication date

1 April 2011

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27 January 2020

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21472142%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

13

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27 January 2020

4

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Europe PubMed Central

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27 January 2020

374-385

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21472142%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Protected from the inside: endogenous histone deacetylase inhibitors and the road to cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Vismodegib, a small-molecule inhibitor of the hedgehog pathway for the treatment of advanced cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Histone deacetylase inhibitors in cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Medulloblastoma: role of developmental pathways, DNA repair signaling, and other players.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Chfr is linked to tumour metastasis through the downregulation of HDAC1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

EnsemblCompara GeneTrees: Complete, duplication-aware phylogenetic trees in vertebrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Pathological and molecular heterogeneity of medulloblastoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Hedgehog: functions and mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Cerebellar granule cells: insights into proliferation, differentiation, and role in medulloblastoma pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Signaling pathways in medulloblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Medulloblastoma in childhood: new biological advances

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

SIRT1 sumoylation regulates its deacetylase activity and cellular response to genotoxic stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Deconstructing the hedgehog pathway in development and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Hedgehog signaling pathway in neural development and disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

HEF1-dependent Aurora A activation induces disassembly of the primary cilium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Born to bind: the BTB protein-protein interaction domain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Morphogen to mitogen: the multiple roles of hedgehog signalling in vertebrate neural development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Mechanisms of disease: Oncogene addiction--a rationale for molecular targeting in cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Alternative splicing of the ErbB-4 cytoplasmic domain and its regulation by hedgehog signaling identify distinct medulloblastoma subsets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

HDAC1 acetylation is linked to progressive modulation of steroid receptor-induced gene transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Modification of proteins by ubiquitin and ubiquitin-like proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Hedgehog antagonist REN(KCTD11) regulates proliferation and apoptosis of developing granule cell progenitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Medulloblastoma: developmental mechanisms out of control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Chromosome 17p deletion in human medulloblastoma: a missing checkpoint in the Hedgehog pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Hedgehog-Gli signalling and the growth of the brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

5 July 2018

Deletions of the short arm of chromosome 3 in solid tumors and the search for suppressor genes.

1 reference

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5 July 2018

Multiple genomic alterations including N-myc amplification in a primary large cell medulloblastoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

28 July 2018

Molecular organization of the cullin E3 ligase adaptor KCTD11.

1 reference

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29 October 2018

The tumor suppressor gene KCTD11REN is regulated by Sp1 and methylation and its expression is reduced in tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

29 October 2018

Medulloblastoma growth inhibition by hedgehog pathway blockade

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3071086

29 October 2018

Molecular genetic studies of chromosome 11 and chromosome 22q DNA sequences in pediatric medulloblastomas.

1 reference

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29 October 2018

Targeting the Hedgehog pathway in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/21472142

12 December 2020

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10.1593/NEO.101630

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21472142%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

PMC publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21472142%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21472142%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

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