(Q42031842)

15 October 2017

Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449 (English)

1 reference

15 October 2017

0 references

9

Stephen E Gould

1 reference

15 October 2017

Charles M Rudin

1

1 reference

15 October 2017

Christine L Hann

2

1 reference

15 October 2017

John Laterra

3

1 reference

15 October 2017

Robert L Yauch

4

1 reference

15 October 2017

Christopher A Callahan

5

1 reference

15 October 2017

Ling Fu

6

1 reference

15 October 2017

Thomas Holcomb

7

1 reference

15 October 2017

Jeremy Stinson

8

1 reference

15 October 2017

Barbara Coleman

10

1 reference

15 October 2017

Patricia M LoRusso

11

1 reference

15 October 2017

Daniel D Von Hoff

12

1 reference

15 October 2017

Frederic J de Sauvage

13

1 reference

15 October 2017

Jennifer A Low

14

1 reference

15 October 2017

language of work or name

English

0 references

publication date

2 September 2009

1 reference

The New England Journal of Medicine

15 October 2017

1 reference

15 October 2017

361

1 reference

15 October 2017

1173-1178

1 reference

15 October 2017

12

1 reference

Inhibition of the hedgehog pathway in advanced basal-cell carcinoma

15 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317279

Medulloblastoma stem cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317279

MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317279

The origins of medulloblastoma subtypes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317279

Medulloblastoma in childhood: new biological advances

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317279

MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317279

Molecular predictors of response to epidermal growth factor receptor antagonists in non-small-cell lung cancer

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317279

New insights into the pathophysiology of chronic myeloid leukemia and imatinib resistance

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317279

Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317279

Orchestrating ontogenesis: variations on a theme by sonic hedgehog

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317279

Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317279

Epidermal growth factor receptor mutations in non-small-cell lung cancer: implications for treatment and tumor biology

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317279

Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317279

Sonic hedgehog promotes G(1) cyclin expression and sustained cell cycle progression in mammalian neuronal precursors

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317279

Metastasis stage, adjuvant treatment, and residual tumor are prognostic factors for medulloblastoma in children: conclusions from the Children's Cancer Group 921 randomized phase III study.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317279

Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317279

Altered neural cell fates and medulloblastoma in mouse patched mutants

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317279

The gene for the naevoid basal cell carcinoma syndrome acts as a tumour-suppressor gene in medulloblastoma

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317279

Transient inhibition of the Hedgehog pathway in young mice causes permanent defects in bone structure

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317279

Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317279

Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317279

A molecular fingerprint for medulloblastoma.

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317279

Medulloblastoma growth inhibition by hedgehog pathway blockade

17 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5317279

17 August 2018

Identifiers

DOI

10.1056/NEJMOA0902903

1 reference

15 October 2017

1 reference

15 October 2017

1 reference