(Q33869550)

29 July 2017

title

Evaluation of thieno[3,2-b]pyrrole[3,2-d]pyridazinones as activators of the tumor cell specific M2 isoform of pyruvate kinase (English)

1 reference

29 July 2017

6

1 reference

29 July 2017

12

1 reference

29 July 2017

9

Christopher P Austin

1 reference

29 July 2017

Craig J Thomas

14

1 reference

ORCID Public Data File 2021

Douglas S Auld

13

object named as

Douglas S Auld

1 reference

29 July 2017

1

Jian-kang Jiang

1 reference

29 July 2017

Matthew G Vander Heiden

3

object named as

Matthew G Vander Heiden

1 reference

29 July 2017

Amanda P Skoumbourdis

5

object named as

Amanda P Skoumbourdis

1 reference

29 July 2017

7

Henrike Veith

1 reference

29 July 2017

Matthew B Boxer

2

1 reference

29 July 2017

Min Shen

4

1 reference

29 July 2017

William Leister

8

1 reference

29 July 2017

Hee Won Park

10

1 reference

29 July 2017

James Inglese

11

1 reference

29 July 2017

language of work or name

English

0 references

publication date

11 April 2010

1 reference

29 July 2017

number of pages

7

1 reference

Bioorganic & Medicinal Chemistry Letters

inferred from page(s)

published in

1 reference

29 July 2017

volume

20

1 reference

29 July 2017

issue

11

1 reference

29 July 2017

page(s)

3387-3393

1 reference

Evaluation of substituted N,N'-diarylsulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase

29 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

Understanding the Warburg effect: the metabolic requirements of cell proliferation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

Brick by brick: metabolism and tumor cell growth

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

Pyruvate kinase M2 is a phosphotyrosine-binding protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

Synthesis and evaluation of new arylbenzo[b]thiophene and diarylthiophene derivatives as inhibitors of the NorA multidrug transporter of Staphylococcus aureus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

Bioluminescent assays for high-throughput screening

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

Pyruvate kinase type M2 and its role in tumor growth and spreading

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

On respiratory impairment in cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

On the Origin of Cancer Cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

The putative effector-binding site of Leishmania mexicana pyruvate kinase studied by site-directed mutagenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

Expression of pyruvate kinase M2 in preneoplastic hepatic foci of N-nitrosomorpholine-treated rats

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

Regulation of pyruvate kinase M gene expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

Alternative splicing of the pyruvate kinase M gene in a minigene system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

Immunohistological demonstration of the same type of pyruvate kinase isoenzyme (M2-Pk) in tumors of chicken and rat

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

The L- and R-type isozymes of rat pyruvate kinase are produced from a single gene by use of different promoters

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

The M1- and M2-type isozymes of rat pyruvate kinase are produced from the same gene by alternative RNA splicing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

Isolation and characterization of the human pyruvate kinase M gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

Regioselective intramolecular reactions of 2-indolylacyl radicals with pyridines: a direct synthetic entry to ellipticine quinones

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

Identification of kinase inhibitors by an ATP depletion method

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

Effect of local molecular structure on the chain-length dependence of the electronic properties of thiophene-based pi-conjugated systems.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

Identification of orally active, potent, and selective 4-piperazinylquinazolines as antagonists of the platelet-derived growth factor receptor tyrosine kinase family

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874658

Quantification of tumor type M2 pyruvate kinase (Tu M2-PK) in human carcinomas

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20451379

12 December 2020

inferred from PubMed ID database lookup

A General and Efficient Copper Catalyst for the Amidation of Aryl Halides and theN-Arylation of Nitrogen Heterocycles

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20451379

12 December 2020

inferred from PubMed ID database lookup

Noncryogenic I/Br-Mg exchange of aromatic halides bearing sensitive functional groups using i-PrMgCl-bis[2-(N,N-dimethylamino)ethyl] ether complexes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20451379

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.BMCL.2010.04.015

1 reference

29 July 2017

1 reference

29 July 2017

1 reference