(Q33870446)

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Shikonin reduces oedema induced by phorbol ester by interfering with IkappaBalpha degradation thus inhibiting translocation of NF-kappaB to the nucleus

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Europe PubMed Central

PubMed publication ID

29 July 2017

Shikonin reduces oedema induced by phorbol ester by interfering with IkappaBalpha degradation thus inhibiting translocation of NF-kappaB to the nucleus (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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author name string

I Andújar

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

M C Recio

2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

T Bacelli

3

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

R M Giner

4

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

J L Ríos

5

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

language of work or name

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publication date

1 May 2010

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Europe PubMed Central

PubMed publication ID

29 July 2017

British Journal of Pharmacology

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Europe PubMed Central

PubMed publication ID

29 July 2017

160

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

376-388

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Shikonin derivatives inhibited LPS-induced NOS in RAW 264.7 cells via downregulation of MAPK/NF-kappaB signaling.

1 reference

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Curcumin decreases 12-O-tetradecanoylphorbol-13-acetate-induced protein kinase C translocation to modulate downstream targets in mouse skin

1 reference

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Isoliquiritigenin isolated from the roots of Glycyrrhiza uralensis inhibits LPS-induced iNOS and COX-2 expression via the attenuation of NF-kappaB in RAW 264.7 macrophages

1 reference

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Anti-inflammatory interventions of NF-kappaB signaling: potential applications and risks

1 reference

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5 July 2018

Inhibition of tumor necrosis factor-alpha through selective blockade of Pre-mRNA splicing by shikonin

1 reference

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5 July 2018

Anti-inflammatory activities of ent-16alphaH,17-hydroxy-kauran-19-oic acid isolated from the roots of Siegesbeckia pubescens are due to the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via NF-kappaB inactivation

1 reference

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Integrating cell-signalling pathways with NF-kappaB and IKK function

1 reference

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Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) suppresses NF-kappaB activation and NF-kappaB-regulated gene products through modulation of p65 and IkappaBalpha kinase activation, leading to potentiation of apoptosis induced by cytokine and chemot

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Inflammation in epithelial skin tumours: old stories and new ideas

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5 July 2018

Nuclear factor kappa B--molecular biomedicine: the next generation

1 reference

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5 July 2018

p53-mediated cell cycle arrest and apoptosis induced by shikonin via a caspase-9-dependent mechanism in human malignant melanoma A375-S2 cells

1 reference

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Shikonins, phytocompounds from Lithospermum erythrorhizon, inhibit the transcriptional activation of human tumor necrosis factor alpha promoter in vivo

1 reference

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5 July 2018

Protein kinase C alpha (PKC alpha): regulation and biological function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874859

5 July 2018

Involvement of NF-kappaB signalling in skin physiology and disease.

1 reference

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5 July 2018

Cellular pharmacology studies of shikonin derivatives.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874859

5 July 2018

Natural products as targeted modulators of the nuclear factor-kappaB pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874859

5 July 2018

Transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874859

5 July 2018

A novel NF-kappa B-inducing kinase-MAPK signaling pathway up-regulates NF-kappa B activity in melanoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874859

5 July 2018

Development and use of a gene promoter-based screen to identify novel inhibitors of cyclooxygenase-2 transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874859

5 July 2018

Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation

1 reference

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Dietary energy restriction inhibits ERK but not JNK or p38 activity in the epidermis of SENCAR mice

1 reference

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5 July 2018

The NF-kappa B-inducing kinase induces PC12 cell differentiation and prevents apoptosis

1 reference

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5 July 2018

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874859

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Chemokines and leukocyte traffic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874859

5 July 2018

The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874859

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NF-kappa B: ten years after

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874859

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Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874859

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Inhibition of hind-paw edema and cutaneous vascular plasma extravasation in mice by acetylshikonin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874859

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Protein kinase C: structure, function, and regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2874859

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Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1 reference

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Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion markers in CD-1 mouse skin by oleandrin

1 reference

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21 January 2018

Curcumin inhibits phorbol ester-induced expression of cyclooxygenase-2 in mouse skin through suppression of extracellular signal-regulated kinase activity and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.00696.X

21 January 2018

Modulation of LPS stimulated NF-kappaB mediated Nitric Oxide production by PKCepsilon and JAK2 in RAW macrophages.

1 reference

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21 January 2018

Inhibitory effect of citrus 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone on 12-O-tetradecanoylphorbol 13-acetate-induced skin inflammation and tumor promotion in mice

1 reference

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Regulation of proinflammatory cytokines in human gestational tissues by peroxisome proliferator-activated receptor-gamma: effect of 15-deoxy-Delta(12,14)-PGJ(2) and troglitazone.

1 reference

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Activation of peroxisome proliferator-activated receptor gamma suppresses inducible cyclooxygenase and nitric oxide synthase during oral mucosal ulcer healing.

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Inhibition of NF-κB activation through targeting IκB kinase by celastrol, a quinone methide triterpenoid

1 reference

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Inhibition of MAP kinase kinase (MEK) results in an anti-inflammatory response in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20423347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of plant phenols on the expression and activity of phorbol ester-induced PKC in mouse epidermis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20423347

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based on heuristic

inferred from PubMed ID database lookup

Mechanisms underlying the inhibitory actions of the pentacyclic triterpene α-amyrin in the mouse skin inflammation induced by phorbol ester 12-O-tetradecanoylphorbol-13-acetate

1 reference

https://pubmed.ncbi.nlm.nih.gov/20423347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Chemistry and Biology of Alkannin, Shikonin, and Related Naphthazarin Natural Products

1 reference

https://pubmed.ncbi.nlm.nih.gov/20423347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[The antiinflammatory activity of shikonin and its inhibitory effect on leukotriene B4 biosynthesis]

1 reference

https://pubmed.ncbi.nlm.nih.gov/20423347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitory effect of acetylshikonin on the activation of NADPH oxidase in polymorphonuclear leukocytes in both whole cell and cell-free systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/20423347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impairment of phosphatidylinositol signaling in acetylshikonin-treated neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/20423347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IkappaB-NF-kappaB structures: at the interface of inflammation control

1 reference

https://pubmed.ncbi.nlm.nih.gov/20423347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1476-5381.2010.00696.X

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

ResearchGate publication ID

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