(Q33877335)

English

A five-year longitudinal analysis of sooty mangabeys naturally infected with simian immunodeficiency virus reveals a slow but progressive decline in CD4+ T-cell count whose magnitude is not predicted by viral load or immune activation

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Europe PubMed Central

PubMed publication ID

29 July 2017

A five-year longitudinal analysis of sooty mangabeys naturally infected with simian immunodeficiency virus reveals a slow but progressive decline in CD4+ T-cell count whose magnitude is not predicted by viral load or immune activation (English)

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29 July 2017

Simian immunodeficiency virus

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Guido Silvestri

9

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Guido Silvestri

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29 July 2017

Mirko Paiardini

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Mirko Paiardini

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29 July 2017

8

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James Else

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29 July 2017

Jessica C Engram

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Jessica Engram

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29 July 2017

2

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Ann Chahroudi

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29 July 2017

author name string

Jessica Taaffe

1

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29 July 2017

Beth Sumpter

4

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29 July 2017

Tracy Meeker

5

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29 July 2017

Sarah Ratcliffe

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29 July 2017

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publication date

24 March 2010

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29 July 2017

Journal of Virology

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29 July 2017

84

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29 July 2017

11

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Europe PubMed Central

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29 July 2017

5476-5484

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys

1 reference

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Lessons learned from the natural hosts of HIV-related viruses

1 reference

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Increased mortality and AIDS-like immunopathology in wild chimpanzees infected with SIVcpz

1 reference

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CD4 downregulation by memory CD4+ T cells in vivo renders African green monkeys resistant to progressive SIVagm infection

1 reference

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T-cell phenotypic and functional changes associated with social subordination and gene polymorphisms in the serotonin reuptake transporter in female rhesus monkeys

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Differential CD4+ T-lymphocyte apoptosis and bystander T-cell activation in rhesus macaques and sooty mangabeys during acute simian immunodeficiency virus infection

1 reference

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Bone marrow-based homeostatic proliferation of mature T cells in nonhuman primates: implications for AIDS pathogenesis

1 reference

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Into the wild: simian immunodeficiency virus (SIV) infection in natural hosts

1 reference

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5 July 2018

Early resolution of acute immune activation and induction of PD-1 in SIV-infected sooty mangabeys distinguishes nonpathogenic from pathogenic infection in rhesus macaques

1 reference

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Short-lived infected cells support virus replication in sooty mangabeys naturally infected with simian immunodeficiency virus: implications for AIDS pathogenesis

1 reference

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Dynamics of T- and B-lymphocyte turnover in a natural host of simian immunodeficiency virus

1 reference

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Understanding the benign nature of SIV infection in natural hosts

1 reference

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5 July 2018

Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection

1 reference

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Acute loss of intestinal CD4+ T cells is not predictive of simian immunodeficiency virus virulence

1 reference

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5 July 2018

Severe depletion of mucosal CD4+ T cells in AIDS-free simian immunodeficiency virus-infected sooty mangabeys

1 reference

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5 July 2018

Depletion of CD8+ cells in sooty mangabey monkeys naturally infected with simian immunodeficiency virus reveals limited role for immune control of virus replication in a natural host species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876601

5 July 2018

Virus subtype-specific features of natural simian immunodeficiency virus SIVsmm infection in sooty mangabeys

1 reference

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Going wild: lessons from naturally occurring T-lymphotropic lentiviruses

1 reference

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5 July 2018

Paucity of CD4+CCR5+ T cells is a typical feature of natural SIV hosts

1 reference

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5 July 2018

Simian immunodeficiency virus SIVagm.sab infection of Caribbean African green monkeys: a new model for the study of SIV pathogenesis in natural hosts

1 reference

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5 July 2018

Primary simian immunodeficiency virus SIVmnd-2 infection in mandrills (Mandrillus sphinx).

1 reference

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5 July 2018

The AIDS resistance of naturally SIV-infected sooty mangabeys is independent of cellular immunity to the virus

1 reference

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5 July 2018

Th-1-type cytotoxic CD8+ T-lymphocyte responses to simian immunodeficiency virus (SIV) are a consistent feature of natural SIV infection in sooty mangabeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876601

5 July 2018

Perturbations of cell cycle control in T cells contribute to the different outcomes of simian immunodeficiency virus infection in rhesus macaques and sooty mangabeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876601

5 July 2018

Timely triggering of homeostatic mechanisms involved in the regulation of T-cell levels in SIVsm-infected sooty mangabeys

1 reference

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Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection

1 reference

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Divergent host responses during primary simian immunodeficiency virus SIVsm infection of natural sooty mangabey and nonnatural rhesus macaque hosts

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Antiinflammatory profiles during primary SIV infection in African green monkeys are associated with protection against AIDS.

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Insufficient production and tissue delivery of CD4+ memory T cells in rapidly progressive simian immunodeficiency virus infection.

1 reference

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CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

1 reference

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Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract

1 reference

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Classic AIDS in a sooty mangabey after an 18-year natural infection

1 reference

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Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy

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Persistent immune activation in HIV-1 infection is associated with progression to AIDS.

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The Ki-67 protein: from the known and the unknown

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Normal T-cell turnover in sooty mangabeys harboring active simian immunodeficiency virus infection

1 reference

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Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes

1 reference

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Simian immunodeficiency virus replicates to high levels in sooty mangabeys without inducing disease

1 reference

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Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection

1 reference

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Plasma viral load and CD4+ lymphocytes as prognostic markers of HIV-1 infection

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Genetic characterization of new West African simian immunodeficiency virus SIVsm: geographic clustering of household-derived SIV strains with human immunodeficiency virus type 2 subtypes and genetically diverse viruses from a single feral sooty mang

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Prognosis in HIV-1 infection predicted by the quantity of virus in plasma

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CD4+ lymphocyte cell enumeration for prediction of clinical course of human immunodeficiency virus disease: a review

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Is the high virulence of HIV-1 an unfortunate coincidence of primate lentiviral evolution?

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Virally induced CD4+ T cell depletion is not sufficient to induce AIDS in a natural host.

1 reference

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Correlates of preserved CD4(+) T cell homeostasis during natural, nonpathogenic simian immunodeficiency virus infection of sooty mangabeys: implications for AIDS pathogenesis

1 reference

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Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells.

1 reference

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T-cell dynamics during acute SIV infection

1 reference

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29 October 2018

Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia

1 reference

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CD4 T cell depletion is linked directly to immune activation in the pathogenesis of HIV-1 and HIV-2 but only indirectly to the viral load.

1 reference

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1 reference

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Development and homeostasis of T cell memory in rhesus macaque

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Immune activation and AIDS pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20335252

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV infection is associated with the spontaneous production off interleukin-1 (IL-1) in vivo and with an abnormal release off IL-1αaL in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/20335252

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated CD38 antigen expression on CD8+ T cells is a stronger marker for the risk of chronic HIV disease progression to AIDS and death in the Multicenter AIDS Cohort Study than CD4+ cell count, soluble immune activation markers, or combinations of

1 reference

https://pubmed.ncbi.nlm.nih.gov/20335252

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of chemokine receptors CXCR4 and CCR5 in HIV-1-infected and uninfected individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/20335252

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CC chemokine receptor 5 cell-surface expression in relation to CC chemokine receptor 5 genotype and the clinical course of HIV-1 infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/20335252

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.00039-10

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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