(Q33882072)

English

Synthesis and anticancer activity of new flavonoid analogs and inconsistencies in assays related to proliferation and viability measurements

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Synthesis and anticancer activity of new flavonoid analogs and inconsistencies in assays related to proliferation and viability measurements (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

author name string

Alaina M Forbes

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Huimin Lin

2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Gary G Meadows

3

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

G Patrick Meier

4

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

publication date

21 May 2014

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

International Journal of Oncology

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

45

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

831-842

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Relationship between the structures of flavonoids and oxygen radical absorbance capacity values: a quantum chemical analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Inhibition effects and induction of apoptosis of flavonoids on the prostate cancer cell line PC-3 in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Grape seed proanthocyanidins reactivate silenced tumor suppressor genes in human skin cancer cells by targeting epigenetic regulators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Genistein enhances the effect of trichostatin A on inhibition of A549 cell growth by increasing expression of TNF receptor-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

An essential difference between the flavonoids monoHER and quercetin in their interplay with the endogenous antioxidant network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Berry flavonoids and phenolics: bioavailability and evidence of protective effects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Dietary quercetin exacerbates the development of estrogen-induced breast tumors in female ACI rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Limitations of MTT and MTS-based assays for measurement of antiproliferative activity of green tea polyphenols

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Bioavailability challenges associated with development of anti-cancer phenolics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Critical appraisal of the MTT assay in the presence of rottlerin and uncouplers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Structurally related cytotoxic effects of flavonoids on human cancer cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Evaluation of silibinin on the viability, migration and adhesion of the human prostate adenocarcinoma (PC-3) cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Role of Bax in quercetin-induced apoptosis in human prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

The ATP/DNA ratio is a better indicator of islet cell viability than the ADP/ATP ratio

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Fisetin, a novel dietary flavonoid, causes apoptosis and cell cycle arrest in human prostate cancer LNCaP cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Anthocyanin inhibits propidium iodide DNA fluorescence in Euphorbia pulcherrima: implications for genome size variation and flow cytometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Cancer chemopreventive properties of orally bioavailable flavonoids--methylated versus unmethylated flavones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

The anti-inflammatory flavones quercetin and kaempferol cause inhibition of inducible nitric oxide synthase, cyclooxygenase-2 and reactive C-protein, and down-regulation of the nuclear factor kappaB pathway in Chang Liver cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Flavonoid oxidation in plants: from biochemical properties to physiological functions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

An overview of halogen bonding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Quercetin downregulates matrix metalloproteinases 2 and 9 proteins expression in prostate cancer cells (PC-3).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Effects of flavonoids on cell proliferation and caspase activation in a human colonic cell line HT29: an SAR study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

A methoxy derivative of resveratrol analogue selectively induced activation of the mitochondrial apoptotic pathway in transformed fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

A flavonoid fraction from cranberry extract inhibits proliferation of human tumor cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Transinactivation of the epidermal growth factor receptor tyrosine kinase and focal adhesion kinase phosphorylation by dietary flavonoids: effect on invasive potential of human carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Inhibition of prostate cancer cell colony formation by the flavonoid quercetin correlates with modulation of specific regulatory genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Palladium-catalyzed Suzuki-Miyaura cross-coupling reactions of potassium aryl- and heteroaryltrifluoroborates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Antiproliferative activities of citrus flavonoids against six human cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

B-ring substituted 5,7-dihydroxyflavonols with high-affinity binding to P-glycoprotein responsible for cell multidrug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Potential health impacts of excessive flavonoid intake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Flavonoids and the inhibition of PKC and PI 3-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: a comparison with tyrosine kinase and protein kinase C inhibition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Mechanism of cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Effect of quercetin on Hoechst 33342 transport by purified and reconstituted P-glycoprotein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

A comparison of active site binding of 4-quinolones and novel flavone gyrase inhibitors to DNA gyrase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Characterization of the cellular reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT): subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Comparison of trypan blue dye exclusion and fluorometric assays for mammalian cell viability determinations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Mutagenicity of plant flavonols in the Salmonella/mammalian microsome test: activation of flavonol glycosides by mixed glycosidases from rat cecal bacteria and other sources

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Mutagenicity of plant flavonoids: Structural requirements for mutagenic activity in Salmonella typhimurium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Mutagenic Activity of Quercetin and Related Compounds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

5 July 2018

Multidrug resistance reversal and apoptosis induction in human colon cancer cells by some flavonoids present in citrus plants.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

29 October 2018

Barbigerone, an isoflavone, inhibits tumor angiogenesis and human non-small-cell lung cancer xenografts growth through VEGFR2 signaling pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

29 October 2018

MTT assay for cell viability: Intracellular localization of the formazan product is in lipid droplets.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

29 October 2018

Limitation of the MTT and XTT assays for measuring cell viability due to superoxide formation induced by nano-scale TiO2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

29 October 2018

Accurate assessment of the bioactivities of redox-active polyphenolics in cell culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

29 October 2018

Novel antiproliferative flavonoids induce cell cycle arrest in human prostate cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

29 October 2018

Evaluation of an automated instrument for viability and concentration measurements of cryopreserved hematopoietic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

29 October 2018

Rhodamine 123 as a probe of mitochondrial membrane potential: evaluation of proton flux through F(0) during ATP synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

29 October 2018

Interference of plant extracts, phytoestrogens and antioxidants with the MTT tetrazolium assay

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

29 October 2018

Resazurin as an electron acceptor in glucose oxidase-catalyzed oxidation of glucose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

29 October 2018

HPC viability measurement: trypan blue versus acridine orange and propidium iodide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4091967

29 October 2018

Aqueous soluble tetrazolium/formazan MTS as an indicator of NADH- and NADPH-dependent dehydrogenase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/24859601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relative bioavailability of the antioxidant flavonoid quercetin from various foods in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/24859601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavonoids suppress androgen-independent human prostate tumor proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24859601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absorption, metabolism and health effects of dietary flavonoids in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/24859601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison of fluorescein diacetate and propidium iodide staining and in vitro excystation for determining Giardia intestinalis cyst viability

1 reference

https://pubmed.ncbi.nlm.nih.gov/24859601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of Kaempferitrin

1 reference

https://pubmed.ncbi.nlm.nih.gov/24859601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic effects of the flavonols quercetin, kaempferol, and galangin on Chinese hamster ovary cells in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/24859601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochemical Demonstration of Ubiquinones in Animal Tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/24859601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of quercetin pharmacokinetics following oral supplementation in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/24859601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Profiling flavonoid cytotoxicity in human breast cancer cell lines: determination of structure-function relationships

1 reference

https://pubmed.ncbi.nlm.nih.gov/24859601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bioavailability of the dietary antioxidant flavonol quercetin in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/24859601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of caspase-dependent, p53-mediated apoptosis by apigenin in human neuroblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/24859601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absorption of flavonols derived from sea buckthorn (Hippophaë rhamnoides L.) and their effect on emerging risk factors for cardiovascular disease in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/24859601

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavonoids of the epigeal part of Glycyrrhiza glabra

1 reference

11 May 2024

https://opencitations.net/index/api/v1/citations/10.1007/BF00574601

Identifiers

10.3892/IJO.2014.2452

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q33882072&oldid=2151603906"