(Q33885097)

English

Redox signaling, alkylation (carbonylation) of conserved cysteines inactivates class I histone deacetylases 1, 2, and 3 and antagonizes their transcriptional repressor function

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Redox signaling, alkylation (carbonylation) of conserved cysteines inactivates class I histone deacetylases 1, 2, and 3 and antagonizes their transcriptional repressor function (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

author name string

Kelly Doyle

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

F A Fitzpatrick

2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

language of work or name

0 references

publication date

12 April 2010

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

number of pages

8

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

285

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

23

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

17417-17424

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Cell signaling by protein carbonylation and decarbonylation

1 reference

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5 July 2018

Genome-wide reduction in H3K9 acetylation during human embryonic stem cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Global analysis of protein damage by the lipid electrophile 4-hydroxy-2-nonenal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment

1 reference

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5 July 2018

Psammaplin A as a general activator of cell-based signaling assays via HDAC inhibition and studies on some bromotyrosine derivatives

1 reference

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5 July 2018

S-Nitrosylation of histone deacetylase 2 induces chromatin remodelling in neurons

1 reference

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5 July 2018

Origin and physiological roles of inflammation

1 reference

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5 July 2018

Oxidative stress and covalent modification of protein with bioactive aldehydes

1 reference

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5 July 2018

Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators

1 reference

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5 July 2018

Routes to 4-hydroxynonenal: fundamental issues in the mechanisms of lipid peroxidation

1 reference

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5 July 2018

Accumulation of 15-deoxy-delta(12,14)-prostaglandin J2 adduct formation with Keap1 over time: effects on potency for intracellular antioxidant defence induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Functional site profiling and electrostatic analysis of cysteines modifiable to cysteine sulfenic acid.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Hematopoietic prostaglandin D2 synthase controls the onset and resolution of acute inflammation through PGD2 and 15-deoxyDelta12 14 PGJ2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

15-Deoxy-Delta(12,14)-prostaglandin J2: an electrophilic trigger of cellular responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Oxidation of 2-Cys-peroxiredoxins by arachidonic acid peroxide metabolites of lipoxygenases and cyclooxygenase-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Prostanoids with cyclopentenone structure as tools for the characterization of electrophilic lipid-protein interactomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Endogenous reactive intermediates as modulators of cell signaling and cell death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Resolution of inflammation: the beginning programs the end

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Reactive lipid species from cyclooxygenase-2 inactivate tumor suppressor LKB1/STK11: cyclopentenone prostaglandins and 4-hydroxy-2-nonenal covalently modify and inhibit the AMP-kinase kinase that modulates cellular energy homeostasis and protein tra

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Differential selectivity of protein modification by the cyclopentenone prostaglandins PGA1 and 15-deoxy-Delta12,14-PGJ2: role of glutathione

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Inhibition of NFkappaB activation and IL-8 expression in human bronchial epithelial cells by acrolein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Protein sulfenic acids in redox signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Protein carbonylation in human diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Points of control in inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Electrophilic prostaglandins and lipid aldehydes repress redox-sensitive transcription factors p53 and hypoxia-inducible factor by impairing the selenoprotein thioredoxin reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

15-Deoxy-Delta(12,14)-prostaglandin J(2): the endogenous electrophile that induces neuronal apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Biological roles and mechanistic actions of co-repressor complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

15-deoxy-delta 12,14-prostaglandin J2. A prostaglandin D2 metabolite generated during inflammatory processes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Transcriptional repression: the long and the short of it.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

15-Deoxy-Delta 12,14-prostaglandin J2 inhibition of NF-kappaB-DNA binding through covalent modification of the p50 subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

IkappaB kinase, a molecular target for inhibition by 4-hydroxy-2-nonenal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

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Histone methylation versus histone acetylation: new insights into epigenetic regulation

1 reference

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Fibroblasts regulate the switch from acute resolving to chronic persistent inflammation.

1 reference

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Beta-catenin-histone deacetylase interactions regulate the transition of LEF1 from a transcriptional repressor to an activator

1 reference

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5 July 2018

15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase

1 reference

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5 July 2018

Sin meets NuRD and other tails of repression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Nuclear histone acetylases and deacetylases and transcriptional regulation: HATs off to HDACs.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Histone acetylation and transcriptional regulatory mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Histone deacetylase activity is required for full transcriptional repression by mSin3A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein. A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsatu

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

5 July 2018

A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878505

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Organic synthesis of prostaglandins: advancing biology

1 reference

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5 July 2018

Possible mutagens derived from lipids and lipid precursors

1 reference

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5 July 2018

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

1 reference

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5 July 2018

The lipid peroxidation product 4-hydroxynonenal facilitates opening of voltage-dependent Ca2+ channels in neurons by increasing protein tyrosine phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.089250

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Acrolein is a product of lipid peroxidation reaction. Formation of free acrolein and its conjugate with lysine residues in oxidized low density lipoproteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.089250

21 January 2018

4-Hydroxy-2-nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.089250

21 January 2018

Formation of reactive cyclopentenone compounds in vivo as products of the isoprostane pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/20385560

12 December 2020

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Inducible cyclooxygenase may have anti-inflammatory properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/20385560

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toward selective histone deacetylase inhibitor design: homology modeling, docking studies, and molecular dynamics simulations of human class I histone deacetylases

1 reference

https://pubmed.ncbi.nlm.nih.gov/20385560

12 December 2020

based on heuristic

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Extraction, purification and analysis of histones

1 reference

https://pubmed.ncbi.nlm.nih.gov/20385560

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein carbonylation as a novel mechanism in redox signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/20385560

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein carbonylation and decarboylation: a new twist to the complex response of vascular cells to oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/20385560

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of histone acetyltransferase and histone deacetylase activities and kinetics of histone acetylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20385560

12 December 2020

based on heuristic

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Albumin-catalyzed metabolism of prostaglandin D2. Identification of products formed in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/20385560

12 December 2020

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Metabolic fate of endogenously synthesized prostaglandin D2 in a human female with mastocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20385560

12 December 2020

based on heuristic

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Site and mechanism of growth inhibition by prostaglandins. I. Active transport and intracellular accumulation of cyclopentenone prostaglandins, a reaction leading to growth inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/20385560

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Site and mechanism of growth inhibition by prostaglandins. II. Temperature-dependent transfer of a cyclopentenone prostaglandin to nuclei

1 reference

https://pubmed.ncbi.nlm.nih.gov/20385560

12 December 2020

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Site and mechanism of growth inhibition by prostaglandins. III. Distribution and binding of prostaglandin A2 and delta 12-prostaglandin J2 in nuclei

1 reference

https://pubmed.ncbi.nlm.nih.gov/20385560

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Identifiers

10.1074/JBC.M109.089250

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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