(Q33886004)

29 July 2017

title

Protein phosphatase-1 activates CDK9 by dephosphorylating Ser175. (English)

1 reference

29 July 2017

Tatiana Ammosova

1

1 reference

29 July 2017

Yuri Obukhov

2

1 reference

29 July 2017

Alexander Kotelkin

3

1 reference

29 July 2017

Denitra Breuer

4

1 reference

29 July 2017

Monique Beullens

5

1 reference

29 July 2017

Victor R Gordeuk

6

1 reference

29 July 2017

Mathieu Bollen

7

1 reference

29 July 2017

Sergei Nekhai

8

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29 July 2017

language of work or name

English

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publication date

21 April 2011

1 reference

29 July 2017

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29 July 2017

volume

6

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29 July 2017

issue

4

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29 July 2017

page(s)

e18985

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Creative Commons Attribution 4.0 International

29 July 2017

copyright license

start time

21 April 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Expression of a protein phosphatase 1 inhibitor, cdNIPP1, increases CDK9 threonine 186 phosphorylation and inhibits HIV-1 transcription

1 reference

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The extended PP1 toolkit: designed to create specificity

28 July 2018

1 reference

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7SK snRNP/P-TEFb couples transcription elongation with alternative splicing and is essential for vertebrate development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080879

The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080879

28 July 2018

1 reference

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PP2B and PP1alpha cooperatively disrupt 7SK snRNP to release P-TEFb for transcription in response to Ca2+ signaling

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080879

LARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associated

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080879

28 July 2018

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Modulation of the Brd4/P-TEFb interaction by the human T-lymphotropic virus type 1 tax protein

28 July 2018

1 reference

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Transcriptional and post-transcriptional regulation of HIV-1 gene expression: role of cellular factors for Tat and Rev.

28 July 2018

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Regulation of transcript elongation through cooperative and ordered recruitment of cofactors

28 July 2018

1 reference

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A novel anticancer agent ARC antagonizes HIV-1 and HCV.

28 July 2018

1 reference

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Tax interacts with P-TEFb in a novel manner to stimulate human T-lymphotropic virus type 1 transcription

28 July 2018

1 reference

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Nuclear targeting of protein phosphatase-1 by HIV-1 Tat protein

28 July 2018

1 reference

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Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080879

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080879

RNA interference directed to CDK2 inhibits HIV-1 transcription

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080879

Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080879

MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080879

Protein phosphatase-1 dephosphorylates the C-terminal domain of RNA polymerase-II

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080879

7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080879

The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080879

Positive transcription elongation factor B phosphorylates hSPT5 and RNA polymerase II carboxyl-terminal domain independently of cyclin-dependent kinase-activating kinase.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080879

The C-terminus of NIPP1 (nuclear inhibitor of protein phosphatase-1) contains a novel binding site for protein phosphatase-1 that is controlled by tyrosine phosphorylation and RNA binding

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080879

CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 tat-P-TEFb complex to TAR RNA

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080879

Cell cycle-dependent stimulation of the HIV-1 promoter by Tat-associated CAK activator

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080879

Identification of multiple cyclin subunits of human P-TEFb

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080879

TAK, an HIV Tat-associated kinase, is a member of the cyclin-dependent family of protein kinases and is induced by activation of peripheral blood lymphocytes and differentiation of promonocytic cell lines

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080879

Transcription elongation factor P-TEFb is required for HIV-1 tat transactivation in vitro

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080879

Dual phosphorylation of the T-loop in cdk7: its role in controlling cyclin H binding and CAK activity.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080879

Preparation of low-molecular-weight forms of rabbit muscle protein phosphatase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080879

Cell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080879

Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme

28 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018985

Analysis of the large inactive P-TEFb complex indicates that it contains one 7SK molecule, a dimer of HEXIM1 or HEXIM2, and two P-TEFb molecules containing Cdk9 phosphorylated at threonine 186

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018985

Phosphorylated positive transcription elongation factor b (P-TEFb) is tagged for inhibition through association with 7SK snRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018985

Regulation of two key nuclear enzymatic activities by the 7SK small nuclear RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018985

Dephosphorylation of CDK9 by protein phosphatase 2A and protein phosphatase-1 in Tat-activated HIV-1 transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018985

Nuclear protein phosphatase-1 regulates HIV-1 transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018985

Cdc25M2 activation of cyclin-dependent kinases by dephosphorylation of threonine-14 and tyrosine-15

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018985

DNA binding provides a signal for phosphorylation of the RNA polymerase II heptapeptide repeats

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21533037

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0018985

1 reference

29 July 2017

0 references

1 reference

29 July 2017

1 reference