(Q33886507)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9171343%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

title

T-cell receptor ligation by peptide/MHC induces activation of a caspase in immature thymocytes: the molecular basis of negative selection (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9171343%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

0 references

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9171343%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

author name string

L K Clayton

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9171343%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

Y Ghendler

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9171343%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

E Mizoguchi

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9171343%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

R J Patch

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9171343%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

T D Ocain

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9171343%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

A K Bhan

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9171343%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

V M Dixit

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9171343%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

E L Reinherz

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9171343%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

language of work or name

English

0 references

publication date

1 May 1997

1 reference

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3 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9171343%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

volume

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9171343%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9171343%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

page(s)

2282-2293

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9171343%20AND%20SRC:MED&resulttype=core&format=json

Different interleukin-1 beta converting enzyme (ICE) family protease requirements for the apoptotic death of T lymphocytes triggered by diverse stimuli

3 November 2019

cites work

1 reference

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Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

5 July 2018

1 reference

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CrmA expression in T lymphocytes of transgenic mice inhibits CD95 (Fas/APO-1)-transduced apoptosis, but does not cause lymphadenopathy or autoimmune disease.

5 July 2018

1 reference

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Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95

5 July 2018

1 reference

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Human ICE/CED-3 protease nomenclature

5 July 2018

1 reference

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In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains

5 July 2018

1 reference

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Molecular ordering of apoptotic mammalian CED-3/ICE-like proteases.

5 July 2018

1 reference

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Proteolytic activation of the cell death protease Yama/CPP32 by granzyme B.

5 July 2018

1 reference

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Molecular thanatopsis: a discourse on the BCL2 family and cell death.

5 July 2018

1 reference

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The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

The molecular biology of apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

Molecular ordering of the cell death pathway. Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptotic proteases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

Toward an understanding of the molecular mechanisms of physiological cell death.

5 July 2018

1 reference

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A novel domain within the 55 kd TNF receptor signals cell death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

T cell receptor antagonist peptides induce positive selection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

Development of the T cell receptor repertoire in lpr mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

P1 aspartate-based peptide alpha-((2,6-dichlorobenzoyl)oxy)methyl ketones as potent time-dependent inhibitors of interleukin-1 beta-converting enzyme

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

Crystal structure of the cysteine protease interleukin-1 beta-converting enzyme: a (p20/p10)2 homodimer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

Structure and mechanism of interleukin-1 beta converting enzyme

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

A general method for facilitating heterodimeric pairing between two proteins: application to expression of alpha and beta T-cell receptor extracellular segments

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

Mechanisms and genes of cellular suicide

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

Apoptosis research enters the ICE age.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

Conversion of the substrate specificity of mouse proteinase granzyme B

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

New perspectives of CD28-B7-mediated T cell costimulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

Fatal interactions: Fas-induced apoptosis of mature T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand

5 July 2018

1 reference

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Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

Deletion of self-reactive thymocytes occurs at a CD4+8+ precursor stage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

Monoclonal antibody-mediated tumor regression by induction of apoptosis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumor necrosis factor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

Peptidyl (acyloxy)methyl ketones and the quiescent affinity label concept: the departing group as a variable structural element in the design of inactivators of cysteine proteinases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

Structure and expression of a cluster of human hematopoietic serine protease genes found on chromosome 14q11.2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

Bcl-2 prevents death of factor-deprived cells but fails to prevent apoptosis in targets of cell mediated killing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

In vivo and in vitro clonal deletion of double-positive thymocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1169830

Regulation of apoptosis and T cell activation by Fas-specific mAb.

5 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2F16.9.2282

Impaired Negative Selection of T Cells in Hodgkin's Disease Antigen CD30–Deficient Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2F16.9.2282

Evidence for a differential avidity model of T cell selection in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2F16.9.2282

1-Hydroxy-7-azabenzotriazole. An efficient peptide coupling additive

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2F16.9.2282

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2F16.9.2282

Transcriptional activation of the human cytotoxic serine protease gene CSP-B in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2F16.9.2282

ICE family proteases: mediators of all apoptotic cell death?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2F16.9.2282

T cell tolerance by clonal elimination in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2F16.9.2282

Cytokine imbalance and autoantibody production in T cell receptor-alpha mutant mice with inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2F16.9.2282

Comparative molecular model building of two serine proteinases from cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2F16.9.2282

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2F16.9.2282

Negative selection of lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2F16.9.2282

Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2F16.9.2282

The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2F16.9.2282

Requirement of an ICE-like protease for induction of apoptosis and ceramide generation by REAPER.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2F16.9.2282

Negative selection of CD4+CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2F16.9.2282

Selective inhibition of interleukin 2 gene function following thymocyte antigen/major histocompatibility complex receptor crosslinking: possible thymic selection mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2F16.9.2282

Identification and characterization of Ich-3, a member of the interleukin-1beta converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2F16.9.2282

Advantageous applications of azabenzotriazole (triazolopyridine)-based coupling reagents to solid-phase peptide synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2F16.9.2282

Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2F16.9.2282

T-cell apoptosis detected in situ during positive and negative selection in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FEMBOJ%2F16.9.2282

Expression of a hybrid immunoglobulin-T cell receptor protein in transgenic mice

21 January 2018

1 reference

12 December 2020

The 5'-flanking region of the human CGL-1/granzyme B gene targets expression of a reporter gene to activated T-lymphocytes in transgenic mice

1 reference

12 December 2020

Transfer of putative complementarity-determining region loops of T cell receptor V domains confers toxin reactivity but not peptide/MHC specificity

1 reference

12 December 2020

Positive and negative thymocyte selection induced by different concentrations of a single peptide

1 reference

12 December 2020

Inactivation of interleukin-1 beta converting enzyme by peptide (acyloxy)methyl ketones

1 reference

12 December 2020

B7 expression on thymic medullary epithelium correlates with epithelium-mediated deletion of V beta 5+ thymocytes

1 reference

12 December 2020

Aspartyl alpha-((1-phenyl-3-(trifluoromethyl)-pyrazol-5-yl)oxy)methyl ketones as interleukin-1 beta converting enzyme inhibitors. Significance of the P1 and P3 amido nitrogens for enzyme-peptide inhibitor binding

1 reference

12 December 2020

An interleukin-1 beta-converting enzyme-like protease is a common mediator of apoptosis in thymocytes

1 reference

12 December 2020

CPP32/apopain is a key interleukin 1 beta converting enzyme-like protease involved in Fas-mediated apoptosis

1 reference

12 December 2020

Identifiers

DOI

10.1093/EMBOJ/16.9.2282

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9171343%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9171343%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

PubMed publication ID

9171343

1 reference