(Q36231231)

12 August 2017

In vivo and in vitro clonal deletion of double-positive thymocytes (English)

1 reference

12 August 2017

0 references

1 reference

10.1084/JEM.175.5.1307

https://api.crossref.org/works/10.1084/JEM.175.5.1307

3 December 2023

2

J. Kaye

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1314886

3 December 2023

author name string

N. J. Vasquez

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1314886

12 September 2022

S. M. Hedrick

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1314886

12 September 2022

language of work or name

English

0 references

publication date

1 May 1992

1 reference

PMCID

2119201

full work available at URL

12 August 2017

https://europepmc.org/articles/PMC2119201

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1314886

https://europepmc.org/articles/PMC2119201?pdf=render

12 September 2022

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1314886

https://rupress.org/jem/article-pdf/175/5/1307/1102430/1307.pdf

12 September 2022

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1314886

https://rupress.org/jem/article-pdf/175/5/1307/1673428/1307.pdf

3 December 2023

file format

Portable Document Format

1 reference

Crossref

DOI

10.1084/JEM.175.5.1307

https://api.crossref.org/works/10.1084/JEM.175.5.1307

Journal of Experimental Medicine

3 December 2023

published in

1 reference

12 August 2017

175

1 reference

12 August 2017

1307-1316

1 reference

12 August 2017

5

1 reference

Both a monoclonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen-presenting cells in the activation of T cells

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

The effects of cyclosporin A on the immune system

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

Predominant use of a V alpha gene segment in mouse T-cell receptors for cytochrome c.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

Early T lymphocytes. Differentiation in vivo of adult intrathymic precursor cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

Developmental biology of T cells in T cell-receptor transgenic mice

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

The actions of cyclosporin A and FK506 suggest a novel step in the activation of T lymphocytes.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

A single stem cell can recolonize an embryonic thymus, producing phenotypically distinct T-cell populations

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

Deletion of self-reactive thymocytes occurs at a CD4+8+ precursor stage

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

Functionally distinct subsites on a class II major histocompatibility complex molecule

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

Correlations between T-cell specificity and the structure of the antigen receptor.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

Abnormal differentiation of thymocytes in mice treated with cyclosporin A.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

The thymus has two functionally distinct populations of immature alpha beta + T cells: one population is deleted by ligation of alpha beta TCR.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

Phenotypic differences between alpha beta versus beta T-cell receptor transgenic mice undergoing negative selection

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

Antigen/MHC-specific T cells are preferentially exported from the thymus in the presence of their MHC ligand.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

Programmed death of autoreactive thymocytes.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

Stimulation of all T cells bearing V beta 1, V beta 3, V beta 11 and V beta 12 by staphylococcal enterotoxin A.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

Inhibition of T cell development in thymic organ culture: implications for the mechanism of action of cyclosporin A.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

Clonal deletion of immature CD4+8+ thymocytes in suspension culture by extrathymic antigen-presenting cells

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

A T cell receptor V alpha region selectively expressed in CD4+ cells

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

Effect of cyclosporin A on lymphopoiesis. II. Developmental defects of immature and mature thymocytes in fetal thymus organ cultures treated with cyclosporin A.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

Residues of the variable region of the T-cell-receptor β-chain that interact with S. aureus toxin superantigens

5 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2119201

The cell cycle block and lysis of an activated T cell hybridoma are distinct processes with different Ca2+ requirements and sensitivity to cyclosporine A

5 December 2018

1 reference

12 December 2020

Identification of the region of T cell receptor β chain that interacts with the self-superantigen MIs-1a

1 reference

12 December 2020

Lower receptor avidity required for thymic clonal deletion than for effector T-cell function

1 reference

12 December 2020

Self-nonself discrimination by T cells

1 reference

12 December 2020

Activation of polyphosphoinositide hydrolysis in T cells by H-2 alloantigen but not MLS determinants

1 reference

12 December 2020

The Vβ-specific superantigen staphylococcal enterotoxin B: Stimulation of mature T cells and clonal deletion in neonatal mice

1 reference

12 December 2020

Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures

1 reference

12 December 2020

Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells

1 reference

12 December 2020

Effects of cyclosporine A on T cell development and clonal deletion

1 reference

12 December 2020

Deletion of self-reactive T cells before entry into the thymus medulla

1 reference

12 December 2020

T cell tolerance by clonal elimination in the thymus

1 reference

12 December 2020

Antigen-induced apoptosis in developing T cells: a mechanism for negative selection of the T cell receptor repertoire

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.175.5.1307

1 reference

12 August 2017

1 reference

12 August 2017

1 reference

PMCID

2119201