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Regulation of basal cellular physiology by the homeostatic unfolded protein response
scientific article
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
2878945
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20513765%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
review article
1 reference
stated in
Europe PubMed Central
title
Regulation of basal cellular physiology by the homeostatic unfolded protein response
(English)
1 reference
stated in
Europe PubMed Central
PMCID
2878945
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20513765%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
main subject
physiological phenomenon
1 reference
stated in
PubMed
retrieved
20 August 2019
regulation of gene expression
1 reference
stated in
PubMed
retrieved
8 September 2019
cell
1 reference
stated in
PubMed
retrieved
12 October 2019
physiology
0 references
author
Ramanujan Shankar Hegde
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
2878945
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20513765%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
Thomas Rutkowski
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
2878945
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20513765%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
author name string
D Thomas Rutkowski
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
20513765
retrieved
29 July 2017
language of work or name
English
0 references
publication date
1 May 2010
1 reference
stated in
Europe PubMed Central
PMCID
2878945
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20513765%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
number of pages
12
1 reference
based on heuristic
inferred from page(s)
published in
Journal of Cell Biology
4 references
stated in
PubMed Central
retrieved
20 August 2019
stated in
PubMed Central
retrieved
8 September 2019
stated in
PubMed Central
retrieved
12 October 2019
stated in
Europe PubMed Central
PMCID
2878945
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20513765%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
volume
189
1 reference
stated in
Europe PubMed Central
PMCID
2878945
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20513765%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
issue
5
1 reference
stated in
Europe PubMed Central
PMCID
2878945
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20513765%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
page(s)
783-794
1 reference
stated in
Europe PubMed Central
PMCID
2878945
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20513765%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
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UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.
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5 July 2018
Real-time redox measurements during endoplasmic reticulum stress reveal interlinked protein folding functions
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Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes
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From endoplasmic-reticulum stress to the inflammatory response
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ATF6alpha-Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo
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Regulation of hepatic lipogenesis by the transcription factor XBP1
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Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice
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IRE1beta inhibits chylomicron production by selectively degrading MTP mRNA.
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Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis
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5 July 2018
IRE1 signaling affects cell fate during the unfolded protein response
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5 July 2018
Transmembrane bZIP transcription factors in ER stress signaling and the unfolded protein response
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5 July 2018
The unfolded protein response of B-lymphocytes: PERK-independent development of antibody-secreting cells
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5 July 2018
PERK-dependent compartmentalization of ERAD and unfolded protein response machineries during ER stress
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5 July 2018
XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks
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5 July 2018
Diseases originating from altered protein quality control in the endoplasmic reticulum.
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5 July 2018
Signal integration in the endoplasmic reticulum unfolded protein response
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5 July 2018
A novel role in cytokinesis reveals a housekeeping function for the unfolded protein response
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5 July 2018
GRP78 induction in cancer: therapeutic and prognostic implications.
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5 July 2018
The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis
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5 July 2018
Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway
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5 July 2018
The MEK/ERK cascade: from signaling specificity to diverse functions
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5 July 2018
Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins
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5 July 2018
The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response
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5 July 2018
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
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5 July 2018
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.
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5 July 2018
Endoplasmic reticulum stress in health and disease
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5 July 2018
Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha
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5 July 2018
Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response
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5 July 2018
pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response
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5 July 2018
On the mechanism of sensing unfolded protein in the endoplasmic reticulum
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5 July 2018
Rapid turnover of unspliced Xbp-1 as a factor that modulates the unfolded protein response
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5 July 2018
Coping with stress: eIF2 kinases and translational control
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5 July 2018
CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism
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5 July 2018
Protein accumulation and neurodegeneration in the woozy mutant mouse is caused by disruption of SIL1, a cochaperone of BiP
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5 July 2018
Endoplasmic reticulum stress response and neurodegeneration
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5 July 2018
Cancer gene discovery in solid tumours using transposon-based somatic mutagenesis in the mouse
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5 July 2018
Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis
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5 July 2018
Resistance to vesicular stomatitis virus infection requires a functional cross talk between the eukaryotic translation initiation factor 2alpha kinases PERK and PKR
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PubMed Central
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5 July 2018
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
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5 July 2018
Endoplasmic reticulum stress triggers an acute proteasome-dependent degradation of ATF6.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
5 July 2018
ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
5 July 2018
PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
5 July 2018
Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
5 July 2018
Underglycosylation of ATF6 as a novel sensing mechanism for activation of the unfolded protein response.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
5 July 2018
Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
5 July 2018
Proteasome inhibitors disrupt the unfolded protein response in myeloma cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
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5 July 2018
Activation signal of nuclear factor-kappa B in response to endoplasmic reticulum stress is transduced via IRE1 and tumor necrosis factor receptor-associated factor 2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
5 July 2018
Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
5 July 2018
Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
5 July 2018
A central role for JNK in obesity and insulin resistance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
5 July 2018
Activation of an unfolded protein response during differentiation of antibody-secreting B cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
5 July 2018
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
5 July 2018
The PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
5 July 2018
Translational control is required for the unfolded protein response and in vivo glucose homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
5 July 2018
Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
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5 July 2018
B cell development pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
5 July 2018
Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
5 July 2018
Perk is essential for translational regulation and cell survival during the unfolded protein response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
5 July 2018
Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
5 July 2018
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
5 July 2018
CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
5 July 2018
Retroviral insertional mutagenesis as a strategy to identify cancer genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
5 July 2018
The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
5 July 2018
The stress response in Chinese hamster ovary cells. Regulation of ERp72 and protein disulfide isomerase expression and secretion.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
5 July 2018
Circadian clock-coordinated 12 Hr period rhythmic activation of the IRE1alpha pathway controls lipid metabolism in mouse liver
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
29 October 2018
The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
29 October 2018
Activation of mammalian IRE1alpha upon ER stress depends on dissociation of BiP rather than on direct interaction with unfolded proteins.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
29 October 2018
B- and T-cell development both involve activity of the unfolded protein response pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
29 October 2018
Ablation of the UPR-mediator CHOP restores motor function and reduces demyelination in Charcot-Marie-Tooth 1B mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
29 October 2018
The role of brain-derived neurotrophic factor (BDNF)-induced XBP1 splicing during brain development.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
29 October 2018
Effects of the isoform-specific characteristics of ATF6 alpha and ATF6 beta on endoplasmic reticulum stress response gene expression and cell viability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
29 October 2018
Reduction of disulfide bridges in the lumenal domain of ATF6 in response to glucose starvation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
29 October 2018
Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
29 October 2018
A transgenic mouse model for monitoring endoplasmic reticulum stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
29 October 2018
Bypassing a Kinase Activity with an ATP-Competitive Drug
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
29 October 2018
The unfolded protein response: an intracellular signalling pathway with many surprising features
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2878945
retrieved
29 October 2018
Identifiers
DOI
10.1083/JCB.201003138
1 reference
stated in
Europe PubMed Central
PMCID
2878945
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20513765%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
PMCID
2878945
1 reference
stated in
Europe PubMed Central
PMCID
2878945
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20513765%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
PubMed ID
20513765
1 reference
stated in
Europe PubMed Central
PMCID
2878945
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20513765%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 February 2020
ResearchGate publication ID
44640870
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