(Q33886988)

English

Reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to a supraphysiologic glucose concentration is associated with loss of STF-1 transcription factor expression

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scholarly article

1 reference

Europe PubMed Central

29 July 2017

Reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to a supraphysiologic glucose concentration is associated with loss of STF-1 transcription factor expression (English)

1 reference

Europe PubMed Central

29 July 2017

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0 references

1 reference

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author name string

L K Olson

1

1 reference

Europe PubMed Central

29 July 2017

A Sharma

2

1 reference

Europe PubMed Central

29 July 2017

M Peshavaria

3

1 reference

Europe PubMed Central

29 July 2017

C V Wright

4

1 reference

Europe PubMed Central

29 July 2017

H C Towle

5

1 reference

Europe PubMed Central

29 July 2017

R P Rodertson

6

1 reference

Europe PubMed Central

29 July 2017

R Stein

7

1 reference

Europe PubMed Central

29 July 2017

language of work or name

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publication date

1 September 1995

1 reference

Europe PubMed Central

29 July 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

29 July 2017

92

1 reference

Europe PubMed Central

29 July 2017

9127-9131

1 reference

Europe PubMed Central

29 July 2017

20

1 reference

Europe PubMed Central

29 July 2017

Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

28 July 2018

Chronic exposure of HIT cells to high glucose concentrations paradoxically decreases insulin gene transcription and alters binding of insulin gene regulatory protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

28 July 2018

Glucose-induced transcription of the insulin gene is mediated by factors required for beta-cell-type-specific expression

1 reference

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28 July 2018

The insulin gene contains multiple transcriptional elements that respond to glucose

1 reference

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Differentiating glucose toxicity from glucose desensitization: a new message from the insulin gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

28 July 2018

Transcriptional regulation of the human insulin gene is dependent on the homeodomain protein STF1/IPF1 acting through the CT boxes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

28 July 2018

IDX-1: a new homeodomain transcription factor expressed in rat pancreatic islets and duodenum that transactivates the somatostatin gene

1 reference

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28 July 2018

Murine Cdx-4 bears striking similarities to the Drosophila caudal gene in its homeodomain sequence and early expression pattern.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

28 July 2018

IPF1, a homeodomain-containing transactivator of the insulin gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

28 July 2018

Characterization of somatostatin transactivating factor-1, a novel homeobox factor that stimulates somatostatin expression in pancreatic islet cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

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Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

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"A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity". Addendum

1 reference

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28 July 2018

Hyperglycaemia as an inducer as well as a consequence of impaired islet cell function and insulin resistance: implications for the management of diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

28 July 2018

A mutational analysis of the insulin gene transcription control region: expression in beta cells is dependent on two related sequences within the enhancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

28 July 2018

GAL4-VP16 is an unusually potent transcriptional activator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

28 July 2018

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

28 July 2018

Glucose regulates preproinsulin messenger RNA levels in a clonal cell line of simian virus 40-transformed B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

28 July 2018

A tissue-specific nuclear factor binds to multiple sites in the human insulin-gene enhancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

28 July 2018

Insulin secretion and cAMP metabolism in HIT cells. Reciprocal and serial passage-dependent relationships

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

28 July 2018

Transcription activation by the adenovirus E1a protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

28 July 2018

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

28 July 2018

Regulation of insulin gene expression by glucose and calcium in transfected primary islet cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

28 July 2018

Glucose induces insulin gene transcription in a murine pancreatic beta-cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

28 July 2018

Preservation of insulin mRNA levels and insulin secretion in HIT cells by avoidance of chronic exposure to high glucose concentrations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

28 July 2018

Definition of the carbohydrate response element of the rat S14 gene. Evidence for a common factor required for carbohydrate regulation of hepatic genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

28 July 2018

The insulin and islet amyloid polypeptide genes contain similar cell-specific promoter elements that bind identical beta-cell nuclear complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

28 July 2018

Multiple elements in the upstream glucokinase promoter contribute to transcription in insulinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

28 July 2018

Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

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Transcriptional regulation of the ovalbumin and conalbumin genes by steroid hormones in chick oviduct

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

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Insulin-promoter-factor 1 is required for pancreas development in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

29 October 2018

Expression of murine STF-1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

29 October 2018

Novel insulin promoter- and enhancer-binding proteins that discriminate between pancreatic alpha- and beta-cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40937

29 October 2018

XIHbox 8, an endoderm-specific Xenopus homeodomain protein, is closely related to a mammalian insulin gene transcription factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/7568086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/7568086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct effect of glucose on the preproinsulin mRNA level in isolated pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/7568086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of glucose on proinsulin messenger RNA in rats in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/7568086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. II. Regulation of insulin mRNA stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/7568086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation and specificity of glucose-stimulated insulin gene expression in human islets of Langerhans

1 reference

https://pubmed.ncbi.nlm.nih.gov/7568086

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.92.20.9127

1 reference

Europe PubMed Central

29 July 2017

1995PNAS...92.9127O

0 references

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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