(Q33892156)

29 July 2017

1 reference

title

Regulation of the G1 phase of the mammalian cell cycle (English)

1 reference

29 July 2017

Donjerkovic D

1

1 reference

PubMed ID

10765979

29 July 2017

Scott DW

series ordinal

2

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29 July 2017

1 March 2000

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29 July 2017

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29 July 2017

10

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29 July 2017

1-16

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29 July 2017

1

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https://scigraph.springernature.com/pub.10.1038/sj.cr.7290031

29 July 2017

0 references

cites work

RB kinases and RB-binding proteins: new points of view

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https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Role of the Rb/E2F pathway in cell growth control

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

The retinoblastoma protein: a master regulator of cell cycle, differentiation and apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Retinoblastoma protein recruits histone deacetylase to repress transcription

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Rb interacts with histone deacetylase to repress transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Deregulated expression of E2F-1 induces cyclin A- and E-associated kinase activities independently from cell cycle position

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Regulated ectopic expression of cyclin D1 induces transcriptional activation of the cdk inhibitor p21 gene without altering cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

E2F3 activity is regulated during the cell cycle and is required for the induction of S phase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Inhibition of E2F-1 transactivation by direct binding of the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

The retinoblastoma protein binds to a family of E2F transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

DRTF1/E2F: an expanding family of heterodimeric transcription factors implicated in cell-cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

E2F Transcription Factor Is a Target for the RB Protein and the Cyclin A Protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

The retinoblastoma protein is phosphorylated during specific phases of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Specific enzymatic dephosphorylation of the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Regulation of transcription by proteins that control the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Principles of CDK regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

The dynamics of cyclin dependent kinase structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

D-type cyclins and their cyclin-dependent kinases: G1 phase integrators of the mitogenic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Inhibitors of mammalian G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Physical interaction of the retinoblastoma protein with human D cyclins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Functional interactions of the retinoblastoma protein with mammalian D-type cyclins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

A cyclin associated with the CDK-activating kinase MO15

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Requirement for tyrosine phosphorylation of Cdk4 in G1 arrest induced by ultraviolet irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

The tumor suppressor protein p16INK4a.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Tumor surveillance via the ARF-p53 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Cyclin E2: a novel CDK2 partner in the late G1 and S phases of the mammalian cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Investigation of the cell cycle regulation of cdk3-associated kinase activity and the role of cdk3 in proliferation and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Structure and cell cycle-regulated transcription of the human cyclin A gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Differential regulation of E2F transactivation by cyclin/cdk2 complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Different roles for cyclins D1 and E in regulation of the G1-to-S transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Cyclin E and c-Myc promote cell proliferation in the presence of p16INK4a and of hypophosphorylated retinoblastoma family proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Inhibition of E2F activity by the cyclin-dependent protein kinase inhibitor p21 in cells expressing or lacking a functional retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

The role of Cdk7 in CAK function, a retro-retrospective

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Cdk7 is essential for mitosis and for in vivo Cdk-activating kinase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Dephosphorylation of Cdk2 Thr160 by the cyclin-dependent kinase-interacting phosphatase KAP in the absence of cyclin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Cdc25 cell-cycle phosphatase as a target of c-myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

E2F and histone deacetylase mediate transforming growth factor beta repression of cdc25A during keratinocyte cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

p21-containing cyclin kinases exist in both active and inactive states

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

New functional activities for the p21 family of CDK inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Cyclin D-CDK subunit arrangement is dependent on the availability of competing INK4 and p21 class inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Complete inhibition of Cdk/cyclin by one molecule of p21(Cip1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

p27Kip1 induces an accumulation of the repressor complexes of E2F and inhibits expression of the E2F-regulated genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

A new pathway for mitogen-dependent cdk2 regulation uncovered in p27(Kip1)-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

p27Kip1 alters the response of cells to mitogen and is part of a cell-intrinsic timer that arrests the cell cycle and initiates differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Role of cyclin A and p27 in anti-IgM induced G1 growth arrest of murine B-cell lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Cytoplasmic displacement of cyclin E-cdk2 inhibitors p21Cip1 and p27Kip1 in anchorage-independent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Translational control of p27Kip1 accumulation during the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Regulation of the cyclin-dependent kinase inhibitor p27 by degradation and phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Cyclin E-CDK2 is a regulator of p27Kip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Cell cycle-dependent phosphorylation of p27 cyclin-dependent kinase (Cdk) inhibitor by cyclin E/Cdk2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Induction of p27Kip1 degradation and anchorage independence by Ras through the MAP kinase signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Myc and Ras collaborate in inducing accumulation of active cyclin E/Cdk2 and E2F.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

c-Myc regulates cyclin D-Cdk4 and -Cdk6 activity but affects cell cycle progression at multiple independent points

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Role of c-myc and CD45 in spontaneous and anti-receptor-induced apoptosis in adult murine B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Induction of cell cycle regulatory proteins in anti-immunoglobulin-stimulated mature B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

The murine gene p27Kip1 is haplo-insufficient for tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

The prognostic significance of altered cyclin-dependent kinase inhibitors in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

p27kip1: a multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Moving protein heads for breakdown

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith–Wiedemann syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

Transcriptional repression. The cancer-chromatin connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

7 January 2021

Cell cycle-dependent regulation of phosphorylation of the human retinoblastoma gene product

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

7 January 2021

The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

7 January 2021

Induction of cell cycle arrest and B cell terminal differentiation by CDK inhibitor p18(INK4c) and IL-6

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

7 January 2021

Cyclin-dependent kinases at the G1-S transition of the mammalian cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

7 January 2021

Cyclin A is required at two points in the human cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

7 January 2021

Cyclin E-induced S phase without activation of the pRb/E2F pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

7 January 2021

Activation of the phosphatase activity of human cdc25A by a cdk2-cyclin E dependent phosphorylation at the G1/S transition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

7 January 2021

Cdk2-dependent phosphorylation of p27 facilitates its Myc-induced release from cyclin E/cdk2 complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

7 January 2021

Myc activation of cyclin E/Cdk2 kinase involves induction of cyclin E gene transcription and inhibition of p27(Kip1) binding to newly formed complexes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

7 January 2021

Activation of c-Myc uncouples DNA replication from activation of G1-cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CR.7290031

7 January 2021

Identifiers

DOI

10.1038/SJ.CR.7290031

1 reference

29 July 2017

1 reference

PubMed ID

10765979