(Q33898260)

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Xenobiotic-metabolizing cytochromes P450 convert prostaglandin endoperoxide to hydroxyheptadecatrienoic acid and the mutagen, malondialdehyde.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10766802%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Xenobiotic-metabolizing cytochromes P450 convert prostaglandin endoperoxide to hydroxyheptadecatrienoic acid and the mutagen, malondialdehyde (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10766802%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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D W Nebert

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10766802%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

L J Marnett

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10766802%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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1 April 2000

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10766802%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Journal of Biological Chemistry

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10766802%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

275

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10766802%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

16

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10766802%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

11784-11790

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PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10766802%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

Prostaglandins from tumours of human large bowel

1 reference

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21 January 2018

A hypothesis: nonsteroidal anti-inflammatory drugs reduce the incidence of large-bowel cancer.

1 reference

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21 January 2018

Aspirin use and reduced risk of fatal colon cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11784

21 January 2018

Relationship between blood plasma prostaglandin E2 and liver and lung metastases in colorectal cancer

1 reference

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21 January 2018

Enhanced secretion of prostaglandin E2 by tissue-fixed macrophages in colonic carcinoma

1 reference

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21 January 2018

Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas

1 reference

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21 January 2018

The relationship between cyclooxygenase-2 expression and colorectal cancer.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11784

21 January 2018

Unequivocal demonstration that malondialdehyde is a mutagen

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11784

21 January 2018

Mutagenicity and cytotoxicity of malonaldehyde in mammalian cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11784

21 January 2018

Investigation of the adducts formed by reaction of malondialdehyde with adenosine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11784

21 January 2018

Naturally occurring carbonyl compounds are mutagens in Salmonella tester strain TA104.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11784

21 January 2018

Identification of adducts formed by reaction of guanine nucleosides with malondialdehyde and structurally related aldehydes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11784

21 January 2018

Prostaglandin endoperoxides. Novel transformations of arachidonic acid in human platelets

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11784

21 January 2018

Conversion of prostaglandin endoperoxides to C17-hydroxy acids catalyzed by human platelet thromboxane synthase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11784

21 January 2018

Kinetic studies on the conversion of prostaglandin endoperoxide PGH2 by thromboxane synthase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11784

21 January 2018

Determinants of steroid hormone bioavailability

1 reference

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21 January 2018

The immunohistochemical localization of drug-metabolizing enzymes in prostate cancer.

1 reference

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21 January 2018

Cytochrome P450 expression in oesophageal cancer

1 reference

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21 January 2018

Expression of CYP1A1 gene in patients with lung cancer: evidence for cigarette smoke-induced gene expression in normal lung tissue and for altered gene regulation in primary pulmonary carcinomas.

1 reference

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21 January 2018

Xenobiotic metabolising enzyme expression in colonic neoplasia

1 reference

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21 January 2018

Effects of diet and ethanol on the expression and localization of cytochromes P450 2E1 and P450 2C7 in the colon of male rats

1 reference

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21 January 2018

Sustained increase in intracellular free calcium and activation of cyclooxygenase-2 expression in mouse hepatoma cells treated with dioxin

1 reference

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21 January 2018

Isolation and Structure of Two Prostaglandin Endoperoxides That Cause Platelet Aggregation

1 reference

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21 January 2018

Detection and Isolation of an Endoperoxide Intermediate in Prostaglandin Biosynthesis

1 reference

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21 January 2018

Expression of modified human cytochrome P450 3A4 in Escherichia coli and purification and reconstitution of the enzyme.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11784

21 January 2018

Expression of modified human cytochrome P450 1A2 in Escherichia coli: stabilization, purification, spectral characterization, and catalytic activities of the enzyme.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11784

21 January 2018

Expression of modified human cytochrome P450 2E1 in Escherichia coli, purification, and spectral and catalytic properties.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11784

21 January 2018

A simple and rapid method for the purification of cytochrome P-450 (form LM4).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11784

21 January 2018

Products, kinetics, and substrate specificity of homogeneous thromboxane synthase from human platelets: development of a novel enzyme assay

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11784

21 January 2018

Identification of thromboxane A2 synthase active site residues by molecular modeling-guided site-directed mutagenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.16.11784

21 January 2018

Identifiers

10.1074/JBC.275.16.11784

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10766802%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10766802%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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