(Q33901399)

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Manipulation of thiocillin variants by prepeptide gene replacement: structure, conformation, and activity of heterocycle substitution mutants

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scholarly article

1 reference

Europe PubMed Central

29 July 2017

Manipulation of thiocillin variants by prepeptide gene replacement: structure, conformation, and activity of heterocycle substitution mutants (English)

1 reference

Europe PubMed Central

29 July 2017

Christopher T. Walsh

4

object named as

Christopher T Walsh

1 reference

Europe PubMed Central

29 July 2017

author name string

Albert A Bowers

1

1 reference

Europe PubMed Central

29 July 2017

Michael G Acker

2

1 reference

Europe PubMed Central

29 July 2017

Alexander Koglin

3

1 reference

Europe PubMed Central

29 July 2017

language of work or name

0 references

publication date

1 June 2010

1 reference

Europe PubMed Central

29 July 2017

Journal of the American Chemical Society

1 reference

Europe PubMed Central

29 July 2017

132

1 reference

Europe PubMed Central

29 July 2017

21

1 reference

Europe PubMed Central

29 July 2017

7519-7527

1 reference

Europe PubMed Central

29 July 2017

Generation of thiocillin variants by prepeptide gene replacement and in vivo processing by Bacillus cereus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Identification of distinct thiopeptide-antibiotic precursor lead compounds using translation machinery assays

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Nosiheptide biosynthesis featuring a unique indole side ring formation on the characteristic thiopeptide framework

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Ribosomal peptide natural products: bridging the ribosomal and nonribosomal worlds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Ribosomally synthesized thiopeptide antibiotics targeting elongation factor Tu.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Thiostrepton biosynthesis: prototype for a new family of bacteriocins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Thiopeptide biosynthesis featuring ribosomally synthesized precursor peptides and conserved posttranslational modifications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Intramolecular cyclizations of polyketide biosynthesis: mining for a "Diels-Alderase"?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Micrococcin, an antibacterial substance formed by a strain of Micrococcus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

From amino acids to heteroaromatics--thiopeptide antibiotics, nature's heterocyclic peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Lantibiotics: peptides of diverse structure and function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Lacticin 481 synthetase phosphorylates its substrate during lantibiotic production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

New developments in lantibiotic biosynthesis and mode of action.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Thiopeptide antibiotics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Lacticin 481: in vitro reconstitution of lantibiotic synthetase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Structure of the macrocycle thiostrepton solved using the anomalous dispersion contribution of sulfur

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Macrophomate synthase: characterization, sequence, and expression in Escherichia coli of the novel enzyme catalyzing unusual multistep transformation of 2-pyrones to benzoates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Structure of an EF-Tu complex with a thiazolyl peptide antibiotic determined at 2.35 A resolution: atomic basis for GE2270A inhibition of EF-Tu

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Thiazole and oxazole peptides: biosynthesis and molecular machinery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Cofactor requirements and reconstitution of microcin B17 synthetase: a multienzyme complex that catalyzes the formation of oxazoles and thiazoles in the antibiotic microcin B17.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Kinetics and regioselectivity of peptide-to-heterocycle conversions by microcin B17 synthetase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Immunological origins of binding and catalysis in a Diels-Alderase antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

From peptide precursors to oxazole and thiazole-containing peptide antibiotics: microcin B17 synthase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Nosiheptide, a sulfur-containing peptide antibiotic isolated from Streptomyces actuosus 40037.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Studies on the formation of transfer ribonucleic acid-ribosome complexes. IV. Effect of antibiotics on steps of bacterial protein synthesis: some new ribosomal inhibitors of translocation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Antibiotic GE2270 a: a novel inhibitor of bacterial protein synthesis. I. Isolation and characterization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Streptomyces laurentii, a new species producing thiostrepton

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

5 July 2018

Total synthesis and stereochemical assignment of micrococcin P1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

29 October 2018

Natural combinatorial peptide libraries in cyanobacterial symbionts of marine ascidians.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

29 October 2018

Total synthesis of antibiotics GE2270A and GE2270T.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

29 October 2018

Structure and mechanism of the lantibiotic cyclase involved in nisin biosynthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

29 October 2018

Discovery of a biologically active thiostrepton fragment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

29 October 2018

Total synthesis of thiostrepton, part 1: construction of the dehydropiperidine/thiazoline-containing macrocycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

29 October 2018

Total synthesis of thiostrepton, part 2: construction of the quinaldic acid macrocycle and final stages of the synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

29 October 2018

Conformation and absolute configuration of nocathiacin I determined by NMR spectroscopy and chiral capillary electrophoresis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

29 October 2018

Initiation factor IF2, thiostrepton and micrococcin prevent the binding of elongation factor G to the Escherichia coli ribosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

29 October 2018

Pyridinyl polythiazole class peptide antibiotic micrococcin P1, secreted by foodborne Staphylococcus equorum WS2733, is biosynthesized nonribosomally

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

29 October 2018

Structural Basis of the Action of Pulvomycin and GE2270 A on Elongation Factor Tu†,‡

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882596

29 October 2018

Synthesis of the Bycroft-Gowland structure of micrococcin P1

1 reference

https://pubmed.ncbi.nlm.nih.gov/20455532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Total synthesis of the thiopeptide amythiamicin D

1 reference

https://pubmed.ncbi.nlm.nih.gov/20455532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Structure of Thiostrepton

1 reference

https://pubmed.ncbi.nlm.nih.gov/20455532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Berninamycin. 2. Products of acidic hydrolysis, methanolysis, and acetolysis of berninamycin A1

1 reference

https://pubmed.ncbi.nlm.nih.gov/20455532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of nosiheptide, a polythiazole-containing antibiotic

1 reference

https://pubmed.ncbi.nlm.nih.gov/20455532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Berninamycin. 3. Total structure of berninamycin A1,2

1 reference

https://pubmed.ncbi.nlm.nih.gov/20455532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Highly modified cysteine-containing antibiotics. Chemical structure and configuration of nosiheptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/20455532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Mode of Action of Berninamycin and the Mechanism of Resistance in the Producing Organism, Streptomyces bernensis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20455532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

13C NMR study of thiostrepton and thiopeptin components

1 reference

https://pubmed.ncbi.nlm.nih.gov/20455532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reexamination of the 1H and 13C NMR spectral assignments of thiostrepton

1 reference

https://pubmed.ncbi.nlm.nih.gov/20455532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibiotic GE2270 a: a novel inhibitor of bacterial protein synthesis. II. Structure elucidation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20455532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Berninamycins B, C, and D, minor metabolites from Streptomyces bernensis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20455532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Revised structure of the antibiotic GE 2270A

1 reference

https://pubmed.ncbi.nlm.nih.gov/20455532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ATP/GTP hydrolysis is required for oxazole and thiazole biosynthesis in the peptide antibiotic microcin B17

1 reference

https://pubmed.ncbi.nlm.nih.gov/20455532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Total Synthesis of the Thiazolyl Peptide GE2270 A

1 reference

https://pubmed.ncbi.nlm.nih.gov/20455532

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JA102339Q

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

1 reference

Europe PubMed Central

29 July 2017

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