(Q33909294)

29 July 2017

title

Profound prevention of experimental brain metastases of breast cancer by temozolomide in an MGMT-dependent manner (English)

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29 July 2017

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10

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29 July 2017

13

Jacek Jassem

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29 July 2017

6

Wojciech Biernat

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29 July 2017

2

Renata Duchnowska

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29 July 2017

14

Patricia S Steeg

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29 July 2017

3

Stephan Woditschka

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29 July 2017

5

Yongzhen Qian

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29 July 2017

Diane Palmieri

1

1 reference

29 July 2017

Emily Hua

4

1 reference

29 July 2017

Katarzyna Sosińska-Mielcarek

7

1 reference

29 July 2017

Brunilde Gril

8

1 reference

29 July 2017

Andreas M Stark

9

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29 July 2017

David J Liewehr

11

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29 July 2017

Seth M Steinberg

12

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29 July 2017

language of work or name

English

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publication date

14 March 2014

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29 July 2017

published in

Clinical Cancer Research

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29 July 2017

volume

20

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29 July 2017

issue

10

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29 July 2017

page(s)

2727-2739

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CNS metastases in breast cancer: old challenge, new frontiers

29 July 2017

cites work

1 reference

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5 July 2018

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5 July 2018

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5 July 2018

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Brain metastases as preventive and therapeutic targets

5 July 2018

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Heterogeneous Blood–Tumor Barrier Permeability Determines Drug Efficacy in Experimental Brain Metastases of Breast Cancer

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Vorinostat inhibits brain metastatic colonization in a model of triple-negative breast cancer and induces DNA double-strand breaks

5 July 2018

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Dose-dense temozolomide regimen for the treatment of brain metastases from melanoma, breast cancer, or lung cancer not amenable to surgery or radiosurgery: a multicenter phase II study.

5 July 2018

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5 July 2018

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Homogeneous MGMT immunoreactivity correlates with an unmethylated MGMT promoter status in brain metastases of various solid tumors

5 July 2018

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Sites of distant recurrence and clinical outcomes in patients with metastatic triple-negative breast cancer: high incidence of central nervous system metastases

5 July 2018

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Effect of lapatinib on the outgrowth of metastatic breast cancer cells to the brain

5 July 2018

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Reactive glia are recruited by highly proliferative brain metastases of breast cancer and promote tumor cell colonization

5 July 2018

1 reference

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Phase II trial of lapatinib for brain metastases in patients with human epidermal growth factor receptor 2-positive breast cancer

5 July 2018

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Prophylactic cranial irradiation in extensive small-cell lung cancer

5 July 2018

1 reference

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Chemotherapy delivery issues in central nervous system malignancy: a reality check.

5 July 2018

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Her-2 overexpression increases the metastatic outgrowth of breast cancer cells in the brain

5 July 2018

1 reference

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ABT-888, an orally active poly(ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models

5 July 2018

1 reference

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The blood-brain barrier and cancer: transporters, treatment, and Trojan horses

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100541

A phase I/II study of lomustine and temozolomide in patients with cerebral metastases from malignant melanoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100541

Toxicity and efficacy of protracted low dose temozolomide for the treatment of low grade gliomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100541

Temozolomide in metastatic breast cancer (MBC): a phase II trial of the National Cancer Institute of Canada - Clinical Trials Group (NCIC-CTG).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100541

In vivo magnetic resonance imaging of single cells in mouse brain with optical validation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100541

Temozolomide (TMZ) combined with cisplatin (CDDP) in patients with brain metastases from solid tumors: a Hellenic Cooperative Oncology Group (HeCOG) Phase II study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100541

Decreased accessibility and lack of activation of ErbB2 in JIMT-1, a herceptin-resistant, MUC4-expressing breast cancer cell line.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100541

Temozolomide in patients with advanced non-small cell lung cancer with and without brain metastases. a phase II study of the EORTC Lung Cancer Group (08965).

5 July 2018

1 reference

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A phase II trial of temozolomide for patients with recurrent or progressive brain metastases

5 July 2018

1 reference

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A bone-seeking clone exhibits different biological properties from the MDA-MB-231 parental human breast cancer cells and a brain-seeking clone in vivo and in vitro

5 July 2018

1 reference

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Temozolomide: a review of its discovery, chemical properties, pre-clinical development and clinical trials

5 July 2018

1 reference

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Chemotherapy induces regression of brain metastases in breast carcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100541

Plasma and tissue disposition of mitozolomide in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100541

Phase I trial of temozolomide (CCRG 81045: M&B 39831: NSC 362856)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100541

Response of brain metastases from breast cancer to systemic chemotherapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100541

Phase I trial combining temozolomide plus lapatinib for the treatment of brain metastases in patients with HER2-positive metastatic breast cancer: the LAPTEM trial.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100541

In vivo characterization of changing blood-tumor barrier permeability in a mouse model of breast cancer metastasis: a complementary magnetic resonance imaging approach.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100541

Central nervous system metastases in patients with HER2-positive metastatic breast cancer: incidence, treatment, and survival in patients from registHER.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100541

Whole-brain radiation therapy plus concomitant temozolomide for the treatment of brain metastases from non-small-cell lung cancer: a randomized, open-label phase II study

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100541

Prognostic value of O6-methylguanine-DNA methyltransferase status in glioblastoma patients, assessed by five different methods

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100541

Phase 2 trial of temozolomide using protracted low-dose and whole-brain radiotherapy for nonsmall cell lung cancer and breast cancer patients with brain metastases.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100541

Phase I study of capecitabine in combination with temozolomide in the treatment of patients with brain metastases from breast carcinoma

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100541

Temozolomide and concomitant whole brain radiotherapy in patients with brain metastases: a phase II randomized trial

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100541

Central nervous system metastases in women who receive trastuzumab-based therapy for metastatic breast carcinoma

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100541

Effect of temozolomide on central nervous system relapse in patients with advanced melanoma

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100541

Temozolomide: a new oral cytotoxic chemotherapeutic agent with promising activity against primary brain tumours

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4100541

Brain metastases of breast cancer

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24634373

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Perspective: The right trials

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24634373

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/1078-0432.CCR-13-2588

1 reference

29 July 2017

1 reference

29 July 2017

1 reference