(Q33910436)

30 July 2017

1 reference

title

Mutational analysis of the structure and function of opioid receptors (English)

1 reference

30 July 2017

1 reference

Law PY

1

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30 July 2017

Wong YH

series ordinal

2

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30 July 2017

Loh HH

series ordinal

3

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30 July 2017

publication date

1 January 1999

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30 July 2017

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30 July 2017

volume

51

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30 July 2017

issue

6

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30 July 2017

page(s)

440-455

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Coupling of opiate receptors to adenylate cyclase: requirement for Na+ and GTP

30 July 2017

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21 January 2018

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Cloning and functional comparison of kappa and delta opioid receptors from mouse brain

21 January 2018

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Cloning and pharmacological characterization of a rat kappa opioid receptor

21 January 2018

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The cloned kappa opioid receptor couples to an N-type calcium current in undifferentiated PC-12 cells

21 January 2018

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Mobilization of Ca2+ from intracellular stores in transfected neuro2a cells by activation of multiple opioid receptor subtypes.

21 January 2018

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Molecular biology of the opioid receptors: structures, functions and distributions.

21 January 2018

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How receptors talk to trimeric G proteins

21 January 2018

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Molecular tinkering of G protein-coupled receptors: an evolutionary success

21 January 2018

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Alternative splicing in the N-terminal extracellular domain of the pituitary adenylate cyclase-activating polypeptide (PACAP) receptor modulates receptor selectivity and relative potencies of PACAP-27 and PACAP-38 in phospholipase C activation

21 January 2018

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Lys583 in the third extracellular loop of the lutropin/choriogonadotropin receptor is critical for signaling

21 January 2018

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Expression and purification of the extracellular ligand binding region of metabotropic glutamate receptor subtype 1.

21 January 2018

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GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2.

21 January 2018

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Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors

21 January 2018

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Heterodimerization is required for the formation of a functional GABA(B) receptor

21 January 2018

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A novel family of genes encoding putative pheromone receptors in mammals

21 January 2018

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An alpha-carbon template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptors

21 January 2018

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Agonists and antagonists bind to different domains of the cloned kappa opioid receptor

21 January 2018

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Location of regions of the opioid receptor involved in selective agonist binding

21 January 2018

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A chimeric study of the molecular basis of affinity and selectivity of the kappa and the delta opioid receptors. Potential role of extracellular domains

21 January 2018

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DAMGO, a mu-opioid receptor selective ligand, distinguishes between mu-and kappa-opioid receptors at a different region from that for the distinction between mu- and delta-opioid receptors

21 January 2018

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DAMGO, a mu-opioid receptor selective agonist, distinguishes between mu- and delta-opioid receptors around their first extracellular loops.

21 January 2018

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Studies on mu and delta opioid receptor selectivity utilizing chimeric and site-mutagenized receptors

21 January 2018

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The region in the mu opioid receptor conferring selectivity for sufentanil over the delta receptor is different from that over the kappa receptor

21 January 2018

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A chimeric analysis of the opioid receptor domains critical for the binding selectivity of mu opioid ligands

21 January 2018

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DAMGO recognizes four residues in the third extracellular loop to discriminate between mu- and kappa-opioid receptors

21 January 2018

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Involvement of Trp-284, Val-296, and Val-297 of the human delta-opioid receptor in binding of delta-selective ligands

21 January 2018

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Mapping the receptor domains critical for the binding selectivity of delta-opioid receptor ligands

21 January 2018

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Novel "restoration of function" mutagenesis strategy to identify amino acids of the delta-opioid receptor involved in ligand binding

21 January 2018

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Functional role of the spatial proximity of Asp114(2.50) in TMH 2 and Asn332(7.49) in TMH 7 of the mu opioid receptor

21 January 2018

1 reference

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Role of aromatic transmembrane residues of the delta-opioid receptor in ligand recognition

21 January 2018

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Kinetics of opiate receptor inactivation by sulfhydryl reagents: evidence for conformational change in presence of sodium ions

21 January 2018

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Studies on inhibition of mu and delta opioid receptor binding by dithiothreitol and N-ethylmaleimide. His223 is critical for mu opioid receptor binding and inactivation by N-ethylmaleimide

21 January 2018

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Construction of a high affinity zinc switch in the kappa-opioid receptor.

21 January 2018

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Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a mu, delta or kappa opioid receptor type

21 January 2018

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Molecular cloning, tissue distribution and chromosomal localization of a novel member of the opioid receptor gene family

21 January 2018

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cDNA cloning and regional distribution of a novel member of the opioid receptor family.

21 January 2018

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ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization

21 January 2018

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cDNA cloning of an orphan opiate receptor gene family member and its splice variant

21 January 2018

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Isolation of a novel cDNA encoding a putative membrane receptor with high homology to the cloned mu, delta, and kappa opioid receptors.

21 January 2018

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Identification of dynorphins as endogenous ligands for an opioid receptor-like orphan receptor

21 January 2018

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Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

21 January 2018

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Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor.

21 January 2018

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Moving from the orphanin FQ receptor to an opioid receptor using four point mutations

21 January 2018

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Determination of the amino acid residue involved in [3H]beta-funaltrexamine covalent binding in the cloned rat mu-opioid receptor

21 January 2018

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Characterization of Irreversible Binding of β-Funaltrexamine to the Cloned Rat μ Opioid Receptor

21 January 2018

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The C-truncated delta-opioid receptor underwent agonist-dependent activation and desensitization

21 January 2018

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Distribution and second messenger coupling of four somatostatin receptor subtypes expressed in brain

21 January 2018

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Selective interactions of mu-opioid receptors with pertussis toxin-sensitive G proteins: involvement of the third intracellular loop and the c-terminal tail in coupling

21 January 2018

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A conserved arginine in the distal third intracellular loop of the mu-opioid receptor is required for G protein activation

21 January 2018

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Calmodulin binding to G protein-coupling domain of opioid receptors

21 January 2018

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A point mutation of the alpha 2-adrenoceptor that blocks coupling to potassium but not calcium currents

21 January 2018

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Mutation of a conserved serine in TM4 of opioid receptors confers full agonistic properties to classical antagonists

21 January 2018

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G protein-coupled receptors. III. New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization

21 January 2018

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Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

21 January 2018

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Differential mu opiate receptor phosphorylation and desensitization induced by agonists and phorbol esters.

21 January 2018

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The absence of a direct correlation between the loss of [D-Ala2, MePhe4,Gly5-ol]Enkephalin inhibition of adenylyl cyclase activity and agonist-induced mu-opioid receptor phosphorylation

21 January 2018

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Role for G protein-coupled receptor kinase in agonist-specific regulation of mu-opioid receptor responsiveness

21 January 2018

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Mu opioid receptor phosphorylation, desensitization, and ligand efficacy

21 January 2018

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Carboxyl terminus of delta opioid receptor is required for agonist-dependent receptor phosphorylation

21 January 2018

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Phosphorylation is not required for dynamin-dependent endocytosis of a truncated mutant opioid receptor

21 January 2018

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Basal phosphorylation of mu opioid receptor is agonist modulated and Ca2+-dependent

21 January 2018

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Mu and delta opioid receptors are differentially desensitized by the coexpression of beta-adrenergic receptor kinase 2 and beta-arrestin 2 in xenopus oocytes

21 January 2018

1 reference

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Agonist-induced desensitization of the mu opioid receptor is determined by threonine 394 preceded by acidic amino acids in the COOH-terminal tail

21 January 2018

1 reference

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Agonist-induced signaling and trafficking of the mu-opioid receptor: role of serine and threonine residues in the third cytoplasmic loop and C-terminal domain.

21 January 2018

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Carboxyl-terminal splicing of the rat mu opioid receptor modulates agonist-mediated internalization and receptor resensitization.

21 January 2018

1 reference

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Selective interference of beta-arrestin 1 with kappa and delta but not mu opioid receptor/G protein coupling

21 January 2018

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Morphine activates opioid receptors without causing their rapid internalization

21 January 2018

1 reference

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Visualization of time-dependent redistribution of delta-opioid receptors in neuronal cells during prolonged agonist exposure

21 January 2018

1 reference

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U50,488H-induced internalization of the human kappa opioid receptor involves a beta-arrestin- and dynamin-dependent mechanism. Kappa receptor internalization is not required for mitogen-activated protein kinase activation

21 January 2018

1 reference

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Morphine-activated opioid receptors elude desensitization by beta-arrestin

21 January 2018

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Delta and kappa opioid receptors are differentially regulated by dynamin-dependent endocytosis when activated by the same alkaloid agonist

21 January 2018

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Role of carboxyl terminus of mu-and delta-opioid receptor in agonist-induced down-regulation

21 January 2018

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Sequestration of the delta opioid receptor. Role of the C terminus in agonist-mediated internalization

21 January 2018

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Identification of serine 356 and serine 363 as the amino acids involved in etorphine-induced down-regulation of the mu-opioid receptor.

21 January 2018

1 reference

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Agonist-specific regulation of delta-opioid receptor trafficking by G protein-coupled receptor kinase and beta-arrestin

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Down-regulation of mu-opioid receptor by full but not partial agonists is independent of G protein coupling

21 January 2018

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Molecular cloning of a rat kappa opioid receptor reveals sequence similarities to the mu and delta opioid receptors

21 January 2018

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Functional coupling of the delta-, mu-, and kappa-opioid receptors to mitogen-activated protein kinase and arachidonate release in Chinese hamster ovary cells.

21 January 2018

1 reference

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Molecular basis of receptor/G-protein-coupling selectivity

21 January 2018

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Towards understanding the role of the first extracellular loop for the binding of peptide hormones to G-protein coupled receptors

21 January 2018

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Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin

21 January 2018

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Constitutive activation of the beta2 adrenergic receptor alters the orientation of its sixth membrane-spanning segment

21 January 2018

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Implication of the first and third extracellular loops of the mu-opioid receptor in the formation of the ligand binding site: a study using chimeric mu-opioid/angiotensin receptors.

21 January 2018

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Effects of C-terminal truncation of the recombinant delta-opioid receptor on phospholipase C and adenylyl cyclase coupling.

21 January 2018

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A simple structure encodes G protein-activating function of the IGF-II/mannose 6-phosphate receptor

21 January 2018

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Distinct differences between morphine- and [D-Ala2,N-MePhe4,Gly-ol5]-enkephalin-mu-opioid receptor complexes demonstrated by cyclic AMP-dependent protein kinase phosphorylation.

21 January 2018

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Site mutation in the rat mu-opioid receptor demonstrates the involvement of calcium/calmodulin-dependent protein kinase II in agonist-mediated desensitization.

21 January 2018

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Regulation of G protein-coupled receptor kinases by calmodulin and localization of the calmodulin binding domain

21 January 2018

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Desensitization of the delta-opioid receptor correlates with its phosphorylation in SK-N-BE cells: involvement of a G protein-coupled receptor kinase.

21 January 2018

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A constitutively internalizing and recycling mutant of the mu-opioid receptor.

21 January 2018

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Thr353, located within the COOH-terminal tail of the delta opiate receptor, is involved in receptor down-regulation

21 January 2018

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An analysis of the conserved residues between halobacterial retinal proteins and G-protein coupled receptors: implications for GPCR modeling

21 January 2018

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10.1002/(SICI)1097-0282(1999)51:6<440::AID-BIP6>3.0.CO;2-T

21 January 2018

Identifiers

DOI

1 reference

30 July 2017

1 reference