(Q33912894)

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The peroxisome proliferator-activated receptor (PPAR) alpha agonist fenofibrate maintains bone mass, while the PPAR gamma agonist pioglitazone exaggerates bone loss, in ovariectomized rats

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2 February 2020

The peroxisome proliferator-activated receptor (PPAR) alpha agonist fenofibrate maintains bone mass, while the PPAR gamma agonist pioglitazone exaggerates bone loss, in ovariectomized rats (English)

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21615901%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Astrid K. Stunes

1

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2 February 2020

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Jan H Waarsing

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2 February 2020

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Irene Westbroek

2

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2 February 2020

Björn I Gustafsson

3

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2 February 2020

Reidar Fossmark

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2 February 2020

Erik F Eriksen

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2 February 2020

Christiane Petzold

7

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2 February 2020

Janne E Reseland

8

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2 February 2020

Unni Syversen

9

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2 February 2020

publication date

26 May 2011

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2 February 2020

BMC Endocrine Disorders

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2 February 2020

11

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2 February 2020

11

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2 February 2020

copyright license

Creative Commons Attribution 2.0 Generic

26 May 2011

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copyright status

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April 2022 Public Data File from Crossref

describes a project that uses

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ImageQuant

2 references

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3127763/fullTextXML

based on heuristic

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CZ Software Mentions: A large dataset of software mentions in the biomedical literature

https://scigraph.springernature.com/pub.10.1186/1472-6823-11-11

0 references

Different skeletal effects of the peroxisome proliferator activated receptor (PPAR)alpha agonist fenofibrate and the PPARgamma agonist pioglitazone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Pathogenesis of age-related osteoporosis: impaired mechano-responsiveness of bone is not the culprit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

The PPARgamma-selective ligand BRL-49653 differentially regulates the fate choices of rat calvaria versus rat bone marrow stromal cell populations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

The bone-adipose axis in obesity and weight loss.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Pioglitazone and dexamethasone induce adipogenesis in D1 bone marrow stromal cell line, but not through the peroxisome proliferator-activated receptor-gamma pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

PPAR-gamma regulates osteoclastogenesis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Skeletal consequences of thiazolidinedione therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Correlation of obesity and osteoporosis: effect of fat mass on the determination of osteoporosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

The effect of thiazolidinediones on adiponectin serum level: a meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Peroxisome proliferator-activated receptors (PPARs) in the control of bone metabolism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Evolution of peroxisome proliferator-activated receptor agonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Rosiglitazone induces decreases in bone mass and strength that are reminiscent of aged bone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

The peroxisome proliferator-activated receptor-gamma agonist rosiglitazone decreases bone formation and bone mineral density in healthy postmenopausal women: a randomized, controlled trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Diabetes, TZDs, and Bone: A Review of the Clinical Evidence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Bone quality--the material and structural basis of bone strength and fragility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Thiazolidinedione use and bone loss in older diabetic adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Short-term pioglitazone treatment prevents free fatty acid-induced hepatic insulin resistance in normal rats: possible role of the resistin and adiponectin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Intracellular signalling pathways activated by leptin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Distinct effects of PPARgamma insufficiency on bone marrow cells, osteoblasts, and osteoclastic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

PPARs: therapeutic targets for metabolic disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Adiponectin and its receptors are expressed in bone-forming cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Resistin, adiponectin, ghrelin, leptin, and proinflammatory cytokines: relationships in obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

The many lives of leptin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Bone is a target for the antidiabetic compound rosiglitazone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Activation of Peroxisome Proliferator-activated Receptor-γ Inhibits the Runx2-mediated Transcription of Osteocalcin in Osteoblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Divergent effects of selective peroxisome proliferator-activated receptor-gamma 2 ligands on adipocyte versus osteoblast differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

The mechanisms of action of PPARs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Leptin is expressed in and secreted from primary cultures of human osteoblasts and promotes bone mineralization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

https://api.crossref.org/works/10.1186%2F1472-6823-11-11

21 January 2018

IL-4 inhibits osteoclast formation through a direct action on osteoclast precursors via peroxisome proliferator-activated receptor gamma 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Centrifugal isolation of bone marrow from bone: an improved method for the recovery and quantitation of bone marrow osteoprogenitor cells from rat tibiae and femurae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Thiazolidinediones inhibit osteoclast-like cell formation and bone resorption in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Inhibition of Osf2/Cbfa1 expression and terminal osteoblast differentiation by PPARgamma2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Thiazolidinediones in the treatment of insulin resistance and type II diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Peroxisome proliferator-activated receptor-gamma activation by thiazolidinediones induces adipogenesis in bone marrow stromal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Peroxisome proliferation and hepatocarcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

5 July 2018

Activation of peroxisome proliferator-activated receptor-gamma inhibits differentiation of preosteoblasts

1 reference

https://api.crossref.org/works/10.1186%2F1472-6823-11-11

21 January 2018

Rosiglitazone impacts negatively on bone by promoting osteoblast/osteocyte apoptosis

1 reference

https://api.crossref.org/works/10.1186%2F1472-6823-11-11

21 January 2018

Rosiglitazone causes bone loss in mice by suppressing osteoblast differentiation and bone formation

1 reference

https://api.crossref.org/works/10.1186%2F1472-6823-11-11

21 January 2018

Enhanced marrow adipogenesis and bone resorption in estrogen-deprived rats treated with the PPARgamma agonist BRL49653 (rosiglitazone).

1 reference

https://api.crossref.org/works/10.1186%2F1472-6823-11-11

21 January 2018

Long-term prediction of three-dimensional bone architecture in simulations of pre-, peri- and post-menopausal microstructural bone remodeling.

1 reference

https://api.crossref.org/works/10.1186%2F1472-6823-11-11

21 January 2018

In vivo assessment of trabecular bone microarchitecture by high-resolution peripheral quantitative computed tomography.

1 reference

https://api.crossref.org/works/10.1186%2F1472-6823-11-11

21 January 2018

Chronic administration of pioglitazone attenuates intracerebroventricular streptozotocin induced-memory impairment in rats.

1 reference

https://api.crossref.org/works/10.1186%2F1472-6823-11-11

21 January 2018

Reduced serum dipeptidyl peptidase-IV after metformin and pioglitazone treatments

1 reference

https://api.crossref.org/works/10.1186%2F1472-6823-11-11

21 January 2018

Quantification of connectivity in cancellous bone, with special emphasis on 3-D reconstructions.

1 reference

https://api.crossref.org/works/10.1186%2F1472-6823-11-11

21 January 2018

Microarray analysis of gene expression changes in mouse liver induced by peroxisome proliferator- activated receptor alpha agonists

1 reference

https://api.crossref.org/works/10.1186%2F1472-6823-11-11

21 January 2018

Rosiglitazone: what went wrong?

1 reference

https://api.crossref.org/works/10.1186%2F1472-6823-11-11

21 January 2018

Activation of peroxisome proliferator-activated receptor gamma inhibits TNF-alpha-mediated osteoclast differentiation in human peripheral monocytes in part via suppression of monocyte chemoattractant protein-1 expression

1 reference

https://api.crossref.org/works/10.1186%2F1472-6823-11-11

21 January 2018

Effects of 1 year of treatment with pioglitazone or rosiglitazone added to glimepiride on lipoprotein (a) and homocysteine concentrations in patients with type 2 diabetes mellitus and metabolic syndrome: a multicenter, randomized, double-blind, cont

1 reference

https://api.crossref.org/works/10.1186%2F1472-6823-11-11

21 January 2018

A comparison of lipid and glycemic effects of pioglitazone and rosiglitazone in patients with type 2 diabetes and dyslipidemia

1 reference

https://api.crossref.org/works/10.1186%2F1472-6823-11-11

21 January 2018

A prospective, randomized comparison of the metabolic effects of pioglitazone or rosiglitazone in patients with type 2 diabetes who were previously treated with troglitazone

1 reference

https://api.crossref.org/works/10.1186%2F1472-6823-11-11

21 January 2018

Leptin stimulates human osteoblastic cell proliferation, de novo collagen synthesis, and mineralization: Impact on differentiation markers, apoptosis, and osteoclastic signaling

1 reference

https://api.crossref.org/works/10.1186%2F1472-6823-11-11

21 January 2018

PPAR Tissue Distribution and Interactions with Other Hormone-Signaling Pathways

1 reference

https://api.crossref.org/works/10.1186%2F1472-6823-11-11

21 January 2018

The peroxisome proliferator activator receptor alpha/delta agonists linoleic acid and bezafibrate upregulate osteoblast differentiation and induce periosteal bone formation in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

29 October 2018

Long-term fluoxetine administration does not result in major changes in bone architecture and strength in growing rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

29 October 2018

Inhibition of NF-kappaB signaling by fenofibrate, a peroxisome proliferator-activated receptor-alpha ligand, presents a therapeutic strategy for rheumatoid arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

29 October 2018

Mineralizing fibroblast-colony-forming assays.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127763

29 October 2018

Effect of PPAR-γ Agonist on Adiponectin Levels in the Metabolic Syndrome: Lessons From the High Fructose Fed Rat Model

1 reference

https://api.crossref.org/works/10.1186%2F1472-6823-11-11

21 January 2018

Utility of the ovariectomized rat as a model for human osteoporosis in drug discovery

1 reference

https://pubmed.ncbi.nlm.nih.gov/21615901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of bone formation by adiponectin through autocrine/paracrine and endocrine pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/21615901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of hypolipemic drugs on the osteoprotegerin - sRANKL system in patients with coronary artery disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/21615901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thiazolidinedione treatment decreases bone mineral density in type 2 diabetic men

1 reference

https://pubmed.ncbi.nlm.nih.gov/21615901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscle contraction increases the in vivo structural strength to the same degree in osteopenic and normal rat tibiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/21615901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A diet supplemented with husks of Plantago ovata reduces the development of endothelial dysfunction, hypertension, and obesity by affecting adiponectin and TNF-alpha in obese Zucker rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21615901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor activators modulate the osteoblastic maturation of MC3T3-E1 preosteoblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/21615901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantification of Bone Microarchitecture with the Structure Model Index

1 reference

https://pubmed.ncbi.nlm.nih.gov/21615901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of peroxisome proliferator-activated receptor-gamma pathway inhibits osteoclast differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21615901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isotretinoin and fenofibrate induce adiposity with distinct effect on metabolic profile in a rat model of the insulin resistance syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/21615901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Surface-specific effects of a PPARgamma agonist, darglitazone, on bone in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21615901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PPAR agonists modulate human osteoclast formation and activity in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/21615901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1472-6823-11-11

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21615901%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21615901%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21615901%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

ResearchGate publication ID

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