(Q33919758)

30 July 2017

title

GLI1 confers profound phenotypic changes upon LNCaP prostate cancer cells that include the acquisition of a hormone independent state (English)

1 reference

30 July 2017

1 reference

Sandeep K Nadendla

1

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30 July 2017

Allon Hazan

2

1 reference

30 July 2017

Matt Ward

3

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30 July 2017

Lisa J Harper

4

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30 July 2017

Karwan Moutasim

5

1 reference

30 July 2017

Lucia S Bianchi

6

1 reference

30 July 2017

Mahmoud Naase

7

1 reference

30 July 2017

Lucy Ghali

8

1 reference

30 July 2017

Gareth J Thomas

9

1 reference

30 July 2017

David M Prowse

10

1 reference

30 July 2017

Michael P Philpott

11

1 reference

30 July 2017

Graham W Neill

12

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30 July 2017

language of work or name

English

0 references

publication date

25 May 2011

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30 July 2017

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30 July 2017

volume

6

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30 July 2017

issue

5

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30 July 2017

page(s)

e20271

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miR 488* inhibits androgen receptor expression in prostate carcinoma cells

30 July 2017

cites work

1 reference

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5 July 2018

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5 July 2018

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Human prostate sphere-forming cells represent a subset of basal epithelial cells capable of glandular regeneration in vivo

5 July 2018

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Microarray analysis reveals potential target genes of NF-kappaB2/p52 in LNCaP prostate cancer cells

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Claudins 1, 3, and 4 protein expression in ER negative breast cancer correlates with markers of the basal phenotype.

5 July 2018

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The role of microRNA-221 and microRNA-222 in androgen-independent prostate cancer cell lines

5 July 2018

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Global gene expression analysis reveals reduced abundance of putative microRNA targets in human prostate tumours

5 July 2018

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Lipocalin 2 promotes breast cancer progression

5 July 2018

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5 July 2018

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Invasive prostate cancer cells are tumor initiating cells that have a stem cell-like genomic signature

5 July 2018

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Expression of Gli1 correlates with the transition of breast cancer cells to estrogen-independent growth

5 July 2018

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Androgenic regulation of hedgehog signaling pathway components in prostate cancer cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Hedgehog pathway inhibitor HhAntag691 is a potent inhibitor of ABCG2/BCRP and ABCB1/Pgp

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

The role of CD133 in normal human prostate stem cells and malignant cancer-initiating cells

5 July 2018

1 reference

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Transcription factor and microRNA regulation in androgen-dependent and -independent prostate cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Comparative expression of Hedgehog ligands at different stages of prostate carcinoma progression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

GLI2 knockdown using an antisense oligonucleotide induces apoptosis and chemosensitizes cells to paclitaxel in androgen-independent prostate cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Novel human glioma-associated oncogene 1 (GLI1) splice variants reveal distinct mechanisms in the terminal transduction of the hedgehog signal

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

GLI1 repression of ERK activity correlates with colony formation and impaired migration in human epidermal keratinocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

CD44+ CD24(-) prostate cells are early cancer progenitor/stem cells that provide a model for patients with poor prognosis

5 July 2018

1 reference

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5 July 2018

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Role of GLI2 transcription factor in growth and tumorigenicity of prostate cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Smad3 is overexpressed in advanced human prostate cancer and necessary for progressive growth of prostate cancer cells in nude mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Widespread deregulation of microRNA expression in human prostate cancer.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Induction of sonic hedgehog mediators by transforming growth factor-beta: Smad3-dependent activation of Gli2 and Gli1 expression in vitro and in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Hierarchical organization of prostate cancer cells in xenograft tumors: the CD44+alpha2beta1+ cell population is enriched in tumor-initiating cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

A gene transcription signature associated with hormone independence in a subset of both breast and prostate cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Cancer stem-like cells in human prostate carcinoma cells DU145: the seeds of the cell line?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Hedgehog is involved in prostate basal cell hyperplasia formation and its progressing towards tumorigenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Claudin-1 immunohistochemistry for distinguishing malignant from benign epithelial lesions of prostate

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Sonic Hedgehog promotes multiple drug resistance by regulation of drug transport

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Hedgehog signaling in the prostate

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Fused kinase is stabilized by Cdc37/Hsp90 and enhances Gli protein levels

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

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5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Selective modulation of Hedgehog/GLI target gene expression by epidermal growth factor signaling in human keratinocytes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Gli2 is targeted for ubiquitination and degradation by beta-TrCP ubiquitin ligase.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

A potential role of alternative splicing in the regulation of the transcriptional activity of human GLI2 in gonadal tissues

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Protein kinase C-delta and mitogen-activated protein/extracellular signal-regulated kinase-1 control GLI activation in hedgehog signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

GLI transcription factors: mediators of oncogenic Hedgehog signalling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Sonic Hedgehog signaling in advanced prostate cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Prospective identification of tumorigenic prostate cancer stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Recent advances on multiple tumorigenic cascades involved in prostatic cancer progression and targeting therapies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Blockade of transforming growth factor-beta signaling suppresses progression of androgen-independent human prostate cancer in nude mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Claudin-1, -3 and -4 proteins and mRNA expression in benign and malignant breast lesions: a research study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Hedgehog signalling in prostate regeneration, neoplasia and metastasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Hedgehog signaling promotes prostate xenograft tumor growth

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Loss of protein kinase Calpha expression may enhance the tumorigenic potential of Gli1 in basal cell carcinoma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

DAVID: Database for Annotation, Visualization, and Integrated Discovery

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

TM4: a free, open-source system for microarray data management and analysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Human prostate epithelial cell-type cDNA libraries and prostate expression patterns

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Expression of basal cell keratins in human prostate cancer metastases and cell lines

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Post-transcriptional regulation of the gli1 oncogene by the expression of alternative 5' untranslated regions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

In vitro modelling of epithelial and stromal interactions in non-malignant and malignant prostates.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Cloning of novel isoforms of the human Gli2 oncogene and their activities to enhance tax-dependent transcription of the human T-cell leukemia virus type 1 genome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Colocalization of basal and luminal cell-type cytokeratins in human prostate cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Analysis and sorting of prostate cancer cell types by flow cytometry

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0020271

In vitro propagation and characterization of neoplastic stem/progenitor-like cells from human prostate cancer tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0020271

Hedgehog signalling in androgen independent prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0020271

The high molecular weight urinary matrix metalloproteinase (MMP) activity is a complex of gelatinase B/MMP-9 and neutrophil gelatinase-associated lipocalin (NGAL). Modulation of MMP-9 activity by NGAL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0020271

Heterogeneous expression of the lipocalin NGAL in primary breast cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0020271

Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3102098

Loss of claudins-1 and -7 and expression of claudins-3 and -4 correlate with prognostic variables in prostatic adenocarcinomas

29 October 2018

1 reference

12 December 2020

Low claudin expression is associated with high Gleason grade in prostate adenocarcinoma

1 reference

12 December 2020

Methylation of the androgen receptor minimal promoter silences transcription in human prostate cancer

1 reference

12 December 2020

Increased incidence of matrix metalloproteinases in urine of cancer patients

1 reference

12 December 2020

Methylation of the androgen receptor promoter CpG island is associated with loss of androgen receptor expression in prostate cancer cells

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0020271

Identifiers

DOI

1 reference

30 July 2017

0 references

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30 July 2017

1 reference